Description
Chlorambucil is a nitrogen mustard anticancer chemotherapeutic that acts as an alkylating agent. Chlorambucil is clinically used to treat chronic lymphocytic leukemia (CLL).
| Product Unit Size | Cost | Quantity | Stock |
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Chlorambucil is a nitrogen mustard anticancer chemotherapeutic that acts as an alkylating agent. Chlorambucil is clinically used to treat chronic lymphocytic leukemia (CLL).
| Cas No. | 305-03-3 |
|---|---|
| Purity | ≥99% |
| Formula | C14H19Cl2NO2 |
| Formula Wt. | 304.21 |
| Chemical Name | 4-[Bis(2-chloroethyl)amino]benzenebutanoic acid |
| IUPAC Name | 4-[4-[bis(2-chloroethyl)amino]phenyl]butanoic acid |
| Synonym | Amboclorin, Leukeran |
| Melting Point | 64-66°C |
| Solubility | Soluble in alcohol, chloroform or acetone (500 mg/mL). Insoluble in water. |
| Appearance | White to off white powder |
| Store Temp | 4°C |
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| Ship Temp | Ambient |
| MSDS | |
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| Info Sheet |
Begleiter A, Mowat M, Israels LG, et al. Chlorambucil in chronic lymphocytic leukemia: mechanism of action. Leuk Lymphoma. 1996 Oct;23(3-4):187-201. PMID: 9031099.
Kundu GC, Schullek JR, Wilson IB. The alkylating properties of chlorambucil. Pharmacol Biochem Behav. 1994 Nov;49(3):621-4. PMID: 7862715.
For use in amino acid analysis.
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