Description
Chlorambucil is a nitrogen mustard anticancer chemotherapeutic that acts as an alkylating agent. Chlorambucil is clinically used to treat chronic lymphocytic leukemia (CLL).
Product Unit Size | Cost | Quantity | Stock |
---|
Chlorambucil is a nitrogen mustard anticancer chemotherapeutic that acts as an alkylating agent. Chlorambucil is clinically used to treat chronic lymphocytic leukemia (CLL).
Cas No. | 305-03-3 |
---|---|
Purity | ≥99% |
Formula | C14H19Cl2NO2 |
Formula Wt. | 304.21 |
Chemical Name | 4-[Bis(2-chloroethyl)amino]benzenebutanoic acid |
IUPAC Name | 4-[4-[bis(2-chloroethyl)amino]phenyl]butanoic acid |
Synonym | Amboclorin, Leukeran |
Melting Point | 64-66°C |
Solubility | Soluble in alcohol, chloroform or acetone (500 mg/mL). Insoluble in water. |
Appearance | White to off white powder |
Store Temp | 4°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Begleiter A, Mowat M, Israels LG, et al. Chlorambucil in chronic lymphocytic leukemia: mechanism of action. Leuk Lymphoma. 1996 Oct;23(3-4):187-201. PMID: 9031099.
Kundu GC, Schullek JR, Wilson IB. The alkylating properties of chlorambucil. Pharmacol Biochem Behav. 1994 Nov;49(3):621-4. PMID: 7862715.
VEGFR1/2/3, PDGFR, c-Kit, RET inhibitor.
Flavonoid found in fruits, vegetables, and grai...
Trichothecene mycotoxin produced by Fusarium.
Sulfonylurea; SUR1 antagonist.
Tyrphostin; IGF-1R inhibitor.
Ellagic acid derivative produced by gut microfl...
Diterpene compound originally found in Rosmarin...
NSAID; COX-1/2 inhibitor.
ITC found in cruciferous vegetables, homolog of...
ACE inhibitor.
Synthetic steroid, contraceptive; PR and glucoc...
mAChR antagonist.
Nucleoside (guanosine) analog; DNA chain termin...
Laminin-derived peptapeptide.
Tricyclic benzonaphthyridinone; mTORC1/2 inhibi...
Kavalactone originally found in Piper methystic...
VEGF-C/Nrp2 inhibitor. Leukotriene receptor ant...
Rifampicin derivative; DNA-dependent RNA polyme...
HIV protease, GLUT4, calpain inhibitor.
PKC and S6 kinase substrate.