Description
Chlorambucil is a nitrogen mustard anticancer chemotherapeutic that acts as an alkylating agent. Chlorambucil is clinically used to treat chronic lymphocytic leukemia (CLL).
Product Unit Size | Cost | Quantity | Stock |
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Chlorambucil is a nitrogen mustard anticancer chemotherapeutic that acts as an alkylating agent. Chlorambucil is clinically used to treat chronic lymphocytic leukemia (CLL).
Cas No. | 305-03-3 |
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Purity | ≥99% |
Formula | C14H19Cl2NO2 |
Formula Wt. | 304.21 |
Chemical Name | 4-[Bis(2-chloroethyl)amino]benzenebutanoic acid |
IUPAC Name | 4-[4-[bis(2-chloroethyl)amino]phenyl]butanoic acid |
Synonym | Amboclorin, Leukeran |
Melting Point | 64-66°C |
Solubility | Soluble in alcohol, chloroform or acetone (500 mg/mL). Insoluble in water. |
Appearance | White to off white powder |
Store Temp | 4°C |
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Ship Temp | Ambient |
MSDS | |
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Info Sheet |
Begleiter A, Mowat M, Israels LG, et al. Chlorambucil in chronic lymphocytic leukemia: mechanism of action. Leuk Lymphoma. 1996 Oct;23(3-4):187-201. PMID: 9031099.
Kundu GC, Schullek JR, Wilson IB. The alkylating properties of chlorambucil. Pharmacol Biochem Behav. 1994 Nov;49(3):621-4. PMID: 7862715.
Regioisomers
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JAK2 inhibitor.
ALK and Ros1 inhibitor, Trk antagonist.
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Isocitrate dehydrogenase inhibitor.
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