Description
Chlorambucil is a nitrogen mustard anticancer chemotherapeutic that acts as an alkylating agent. Chlorambucil is clinically used to treat chronic lymphocytic leukemia (CLL).
Product Unit Size | Cost | Quantity | Stock |
---|
Chlorambucil is a nitrogen mustard anticancer chemotherapeutic that acts as an alkylating agent. Chlorambucil is clinically used to treat chronic lymphocytic leukemia (CLL).
Cas No. | 305-03-3 |
---|---|
Purity | ≥99% |
Formula | C14H19Cl2NO2 |
Formula Wt. | 304.21 |
Chemical Name | 4-[Bis(2-chloroethyl)amino]benzenebutanoic acid |
IUPAC Name | 4-[4-[bis(2-chloroethyl)amino]phenyl]butanoic acid |
Synonym | Amboclorin, Leukeran |
Melting Point | 64-66°C |
Solubility | Soluble in alcohol, chloroform or acetone (500 mg/mL). Insoluble in water. |
Appearance | White to off white powder |
Store Temp | 4°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Begleiter A, Mowat M, Israels LG, et al. Chlorambucil in chronic lymphocytic leukemia: mechanism of action. Leuk Lymphoma. 1996 Oct;23(3-4):187-201. PMID: 9031099.
Kundu GC, Schullek JR, Wilson IB. The alkylating properties of chlorambucil. Pharmacol Biochem Behav. 1994 Nov;49(3):621-4. PMID: 7862715.
AMPK activator.
JNK, ALK, p38 MAPK inhibitor.
May be useful against COVID-19
Dihydropyridine, FIASMA; L-type Ca2+ channel bl...
Flavanone found in species of Citrus; L-type Ca...
Nitrogen mustard, DNA alkylator.
Fluoroquinolone; topoisomerase IV, topoisomeras...
Peptide, involved in paracrine and autocrine ce...
ITC, erucin analog.
Electron carrier used to study dehydrogenase el...
Smo inhibitor.
SIRT1/2 inhibitor, indirect p53 activator.
Antimicrobial peptide found in Vespula lewisii,...
Bisphosphonate; FPPS inhibitor.
Inhibitor of PI3K.
PDE3/5 inhibitor, LTD4 antagonist.
Alternaria mycotoxin which may be found in food...
Found in Evodia rutaecarpa; potential cAMP, 3β...
Atypical amino acid found in Isaria sinclairi, ...
Antimicrobial peptide, generated during fibrin ...