LKT Labs

Biochemicals for Life Science Research

Clofibric Acid

Clofibric Acid

Product ID C4556
Cas No. 882-09-7
Purity ≥98%
Product Unit SizeCostQuantityStock
10 g $52.00 In stock
50 g $83.00 In stock
Bulk Quote

Quicklinks

Description

Clofibric acid is a metabolite of clofibrate that activates PPARα receptors and inhibits auxin activity, exhibiting anti-hyperlipidemic, anti-angiogenic, anticancer chemotherapeutic, and herbicidal activity. Clofibric acid alters plant hormone activity and is used as a plant growth regulator. Clofibric acid also inhibits phosphatidylethanolamine synthesis, decreasing production of cholesterol and activity of HMG-CoA reductase and ACAT. Additionally, clofibric acid suppresses production of prostaglandin E2 (PGE2) and VEGF, decreases vessel density, and inhibits tumor growth in animal models of ovarian cancer.

Product Info

Cas No.

882-09-7
Purity

≥98%
Formula

C10H11ClO3
Formula Wt.

214.65
Chemical Name

2-(4-Chlorophenoxy)-2-methylpropanoic acid
IUPAC Name

2-(4-chlorophenoxy)-2-methylpropanoic acid
Synonym

Chlorfibrinic acid, Arteriohom, Regulipid
Melting Point

118-119°C

Appearance

Light Yellow Fine Crystalline Powder

Shipping and Storage

Store Temp

Ambient
Ship Temp

Ambient

Downloads

MSDS

C4556 MSDS PDF
Info Sheet

C4556 Info Sheet PDF

References

Yokoyama Y, Xin B, Shigeto T, et al. Clofibric acid, a peroxisome proliferator-activated receptor alpha ligand, inhibits growth of human ovarian cancer. Mol Cancer Ther. 2007 Apr;6(4):1379-86. PMID: 17431116.

Nishimaki-Mogami T, Suzuki K, Okochi E, et al. Bezafibrate and clofibric acid are novel inhibitors of phosphatidylcholine synthesis via the methylation of phosphatidylethanolamine. Biochim Biophys Acta. 1996 Nov 11;1304(1):11-20. PMID: 8944746.

Haughom B, Spydevold O. The mechanism underlying the hypolipemic effect of perfluorooctanoic acid (PFOA), perfluorooctane sulphonic acid (PFOSA) and clofibric acid. Biochim Biophys Acta. 1992 Sep 22;1128(1):65-72. PMID: 1327145.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • E6997

    Erythropoietin, Human Recombinant

    Endogenous glycoprotein hormone involved in red...

    ≥97%
  • B1979

    Betulinic Acid

    Pentacyclic triterpene.

    ≥99%
  • F4483

    Flufenamic Acid

    NSAID; TREK1 K+ potentiator, voltage-gated Na+ ...

    ≥97%
  • U482046

    (-)-Umbellulone

    Antimicrobial found in essential oils from plan...

    ≥98%
  • M704793

    MRTX1719

    PRMT5/MTA complex inhibitor

    ≥95%
  • K0133

    Kainic Acid

    Excitatory amino acid found in seaweed; AMPA an...

    ≥98%
  • A9662

    AZ-628

    B-Raf and c-Raf inhibitor.

    ≥96%
  • V1810

    Vecuronium Bromide

    Non-depolarizing NMJ blocker; nAChR antagonist....

    ≥98%
  • I0801

    IC261

    Casein kinase 1 inhibitor.

    ≥98%
  • T8020

    Tuftsin

    Tetrapeptide, IgG Fc region derivative; Nrp1 ag...

    ≥95%
  • V5254

    Vincristine Sulfate

    Vinca alkaloid found in Catharanthus; microtubu...

    ≥98%
  • B0133

    Baicalin

    Flavone found in Scutellaria; prolyl oligopepti...

    ≥95%
  • N8277

    Nutlin-3

    Imidzoline derivative; MDM2 inhibitor.

    ≥95%
  • A4402

    L-Alaninol

    Amino acid alcohol.

    ≥98%
  • P7718

    Pterostilbene

    Stilbene, resveratrol analog.

    ≥98%
  • R2713

    Recombinant HCV-NS4 Antigens

    Recombinant HCV antigen fragment.

    ≥95%
  • T162051

    Tebipenem

    Broad-spectrum antibiotic

    ≥99%
  • P5747

    Polymyxin B sulfate

    Cationic lipid polypeptide, mixture of polymyxi...

    ≥6500 iu/mg
  • M1605

    Mebendazole

    Benzimidazole; microtubule polymerization inhib...

    ≥98%
  • O938582

    41-Oxo-rapamycin

    Impurity of rapamycin

    ≥95%