LKT Labs

Biochemicals for Life Science Research

Clofibric Acid

Clofibric Acid

Product ID C4556
Cas No. 882-09-7
Purity ≥98%
Product Unit SizeCostQuantityStock
10 g $52.20 In stock
50 g $82.70 In stock
Bulk Quote

Quicklinks

Description

Clofibric acid is a metabolite of clofibrate that activates PPARα receptors and inhibits auxin activity, exhibiting anti-hyperlipidemic, anti-angiogenic, anticancer chemotherapeutic, and herbicidal activity. Clofibric acid alters plant hormone activity and is used as a plant growth regulator. Clofibric acid also inhibits phosphatidylethanolamine synthesis, decreasing production of cholesterol and activity of HMG-CoA reductase and ACAT. Additionally, clofibric acid suppresses production of prostaglandin E2 (PGE2) and VEGF, decreases vessel density, and inhibits tumor growth in animal models of ovarian cancer.

Product Info

Cas No.

882-09-7
Purity

≥98%
Formula

C10H11ClO3
Formula Wt.

214.65
Chemical Name

2-(4-Chlorophenoxy)-2-methylpropanoic acid
IUPAC Name

2-(4-chlorophenoxy)-2-methylpropanoic acid
Synonym

Chlorfibrinic acid, Arteriohom, Regulipid
Melting Point

118-119°C

Appearance

Light Yellow Fine Crystalline Powder

Shipping and Storage

Store Temp

Ambient
Ship Temp

Ambient

Downloads

MSDS

C4556 MSDS PDF
Info Sheet

C4556 Info Sheet PDF

References

Yokoyama Y, Xin B, Shigeto T, et al. Clofibric acid, a peroxisome proliferator-activated receptor alpha ligand, inhibits growth of human ovarian cancer. Mol Cancer Ther. 2007 Apr;6(4):1379-86. PMID: 17431116.

Nishimaki-Mogami T, Suzuki K, Okochi E, et al. Bezafibrate and clofibric acid are novel inhibitors of phosphatidylcholine synthesis via the methylation of phosphatidylethanolamine. Biochim Biophys Acta. 1996 Nov 11;1304(1):11-20. PMID: 8944746.

Haughom B, Spydevold O. The mechanism underlying the hypolipemic effect of perfluorooctanoic acid (PFOA), perfluorooctane sulphonic acid (PFOSA) and clofibric acid. Biochim Biophys Acta. 1992 Sep 22;1128(1):65-72. PMID: 1327145.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • M4004

    MK-2461

    MET, FGFR, PDGFR inhibitor.

    ≥99%
  • N1894

    Nexturastat A

    HDAC6 inhibitor.

    ≥98%
  • P8117

    Puerarin, High Purity

    Isoflavone found in Pueraria; 5-HT2C and GABA-A...

    ≥99%
  • B4517

    Bleomycin A5 Hydrochloride

    Glycopeptide, induces DNA strand breaks.  
    ≥90%
  • T1027

    2’-Benzoylcarbonyl D-seco-Taxol

    2’-Benzoylcarbonyl D-seco-Taxol is an impurit...

    ≥90%
  • L0076

    Latrunculin A

    Thiazolidine macrolide found in the Red Sea spo...
  • A5275

    [Des-Asp1]-Angiotensin I, human

    Peptide, derivative of AT I, cleavage product o...

    ≥95%
  • A1592

    ADX-47273

    mGluR5 positive modulator.

    ≥98%
  • P7359

    Psoralidin

    Phenol found in Psoralea coryfolia.

    ≥98%
  • R0351

    Ramoplanin

    Peptide; peptidoglycan inhibitor.

    ≥90%
  • B1640

    Benzydamine Hydrochloride

    NSAID; PG synthetase inhibitor.

    ≥98%
  • F8147

    Fulvestrant

    Induces ER degradation.

    ≥98%
  • W4096

    WKYMVM-NH2

    Synthetic peptide; FPRL1 agonist.

    ≥95%
  • A9803

    Azathioprine

    Purine nucleotide analog, mercaptiopurine prodr...

    ≥98%
  • I4961

    Imperatorin

    Furocoumarin; voltage-gated Na+ channel blocker...

    ≥98%
  • I0416

    Iberin

    Isothiocyanate found in cruciferous vegetables,...

    ≥97%
  • H0142

    Haloperidol

    Butyrophenone; σ2 agonist, α1-adrenergic, D2,...

    ≥95%
  • N3310

    Nicotinamide

    Amide form of vitamin B3 required for productio...

    ≥98%
  • G7440

    GSK-1120212

    MEK1/2 inhibitor.

    ≥98%
  • I7478

    Istradefylline

    Adenosine A2A antagonist.

    ≥99%