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Corticotropin Releasing Factor, human/rat

Corticotropin Releasing Factor, human/rat

Product ID C5772
Cas No. 86784-80-7
Purity ≥98%
Product Unit SizeCostQuantityStock
0.5 mg $408.90 Please Inquire
1 mg $694.90 Please Inquire
2.5 mg $1,226.60 Please Inquire
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Corticotropin-releasing factor (CRF) is an endogenous neuropeptide hormone that is involved in stress responses, depression, anxiety, and other mood disorders. CRF binds CRF receptors, stimulating release of adrenocorticotropic hormone (ACTH), cortisol, dehydroepiandrosterone (DHEA), and β-endorphin. CRF also modulates the duration of pregnancy and stimulates release of dehydroepiandrosterone (DHEA) in the fetal adrenal gland. High levels of CRF may be used as a biomarker to detect Alzheimer’s disease or major depression.

Product Info

Cas No.

86784-80-7

Purity

≥98%

Formula

C208H344N60O63S2

Formula Wt.

4757.49

Synonym

CRF

Solubility

Soluble in water(1 mg/mL).

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

C5772 MSDS PDF

Info Sheet

C5772 Info Sheet PDF

References

Lowry CA, Moore FL. Regulation of behavioral responses by corticotropin-releasing factor. Gen Comp Endocrinol. 2006 Mar;146(1):19-27. PMID: 16426606.

Arborelius L, Owens MJ, Plotsky PM, et al. The role of corticotropin-releasing factor in depression and anxiety disorders. J Endocrinol. 1999 Jan;160(1):1-12. PMID: 9854171.

Raadsheer FC, van Heerikhuize JJ, Lucassen PJ, et al. Corticotropin-releasing hormone mRNA levels in the paraventricular nucleus of patients with Alzheimer's disease and depression. Am J Psychiatry. 1995 Sep;152(9):1372-6. PMID: 7653697.

Lederis KP, Okawara Y, Richter D, et al. Evolutionary aspects of corticotropin releasing hormones. Prog Clin Biol Res. 1990;342:467-72. PMID: 2200028.

Custom Order

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  • This field is for validation purposes and should be left unchanged.

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