Description
CVT-313 is a potent and selective inhibitor of cyclin-dependent kinase 2 (CDK2).
Product Unit Size | Cost | Quantity | Stock |
---|
CVT-313 is a potent and selective inhibitor of cyclin-dependent kinase 2 (CDK2).
Cas No. | 199986-75-9 |
---|---|
Purity | ≥98% |
Formula | C22H28N6O3 |
Formula Wt. | 400.48 |
IUPAC Name | 2,2'-({9-Isopropyl-6-[(4-methoxybenzyl)amino]-9H-purin-2-yl}imino)diethanol |
Synonym | CVT313; Cdk2 Inhibitor III; Cyclin-dependent kinase 2 Inhibitor III |
Store Temp | -20°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Brooks E., Gray N., et al. CVT-313, a specific and potent inhibitor of CDK2 that prevents neointimal proliferation. J Biol Chem. 272(46):29207-11 (1997). PMID: 9360999.
Faber A., Chiles T. Inhibition of cyclin-dependent kinase-2 induces apoptosis in human diffuse large B-cell lymphomas. Cell Cycle. 6(23):2982-9 (2007). PMID: 18156799.
SHP2 inhibitor
Endogenous opioid peptide; μOr agonist.
Ansamycin; bacterial DNA-dependent RNA polymera...
Selective 5-HT6 receptor antagonist
HIV and AIDS
Abl inhibitor.
Non-proteinogenic amino acid, L-arginine metabo...
Aza-anthracenedione, DNA intercalator; topoisom...
Lignan found in species of Magnolia; GABA-A pot...
Endogenous peptide, involved in paracrine and a...
p110α and p110γ PI3K inhibitor.
O-methylated flavone found in vetch and various...
Endogenous hormone neurotransmitter, involved i...
SYK/JAK inhibitor
Peptide, GLP-1 analog found in Heloderma; GLP-1...
MAO-A inhibitor.
Hydroxycinnamic aicd, verbascoside metabolite, ...
PDE3 inhibitor.
Nicotinic acid derivative; InhA inhibitor.
Furocoumarin; voltage-gated Na+ channel blocker...