Description
CVT-313 is a potent and selective inhibitor of cyclin-dependent kinase 2 (CDK2).
Product Unit Size | Cost | Quantity | Stock |
---|
CVT-313 is a potent and selective inhibitor of cyclin-dependent kinase 2 (CDK2).
Cas No. | 199986-75-9 |
---|---|
Purity | ≥98% |
Formula | C22H28N6O3 |
Formula Wt. | 400.48 |
IUPAC Name | 2,2'-({9-Isopropyl-6-[(4-methoxybenzyl)amino]-9H-purin-2-yl}imino)diethanol |
Synonym | CVT313; Cdk2 Inhibitor III; Cyclin-dependent kinase 2 Inhibitor III |
Store Temp | -20°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Brooks E., Gray N., et al. CVT-313, a specific and potent inhibitor of CDK2 that prevents neointimal proliferation. J Biol Chem. 272(46):29207-11 (1997). PMID: 9360999.
Faber A., Chiles T. Inhibition of cyclin-dependent kinase-2 induces apoptosis in human diffuse large B-cell lymphomas. Cell Cycle. 6(23):2982-9 (2007). PMID: 18156799.
Nucleoside (thymidine) analog; RT inhibitor.
Carnitine derivative, involved in energy homeos...
Endogenous neuropeptide hormone, lowers extrace...
Endogenous proneurotensin peptide, involved in ...
Selective inhibitor of the γ isoform of PI3K (...
Stearoyl-coA desaturase 1 inhibitor.
Alkaloid found in Corydalis and Stephania; D1/2...
EGFR inhibitor.
Hec1/Nek2 mitotic pathway inhibitor
NSAID; COX-1/2 inhibitor.
Pentacyclic triterpene found in the Banaba plan...
PRMT5/MTA complex inhibitor
ATR inhibitor.
Triterpene sapogenin found in species of Panax;...
Natriuretic, vasodilatory peptide, bradykinin a...
Mouse selective STING agonist.
A peroxisome proliferator-activated receptor ag...
Endogenous RF-amide peptide, involved in nocice...