Description
CVT-313 is a potent and selective inhibitor of cyclin-dependent kinase 2 (CDK2).
Product Unit Size | Cost | Quantity | Stock |
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CVT-313 is a potent and selective inhibitor of cyclin-dependent kinase 2 (CDK2).
Cas No. | 199986-75-9 |
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Purity | ≥98% |
Formula | C22H28N6O3 |
Formula Wt. | 400.48 |
IUPAC Name | 2,2'-({9-Isopropyl-6-[(4-methoxybenzyl)amino]-9H-purin-2-yl}imino)diethanol |
Synonym | CVT313; Cdk2 Inhibitor III; Cyclin-dependent kinase 2 Inhibitor III |
Store Temp | -20°C |
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Ship Temp | Ambient |
MSDS | |
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Info Sheet |
Brooks E., Gray N., et al. CVT-313, a specific and potent inhibitor of CDK2 that prevents neointimal proliferation. J Biol Chem. 272(46):29207-11 (1997). PMID: 9360999.
Faber A., Chiles T. Inhibition of cyclin-dependent kinase-2 induces apoptosis in human diffuse large B-cell lymphomas. Cell Cycle. 6(23):2982-9 (2007). PMID: 18156799.
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