Description
CVT-313 is a potent and selective inhibitor of cyclin-dependent kinase 2 (CDK2).
| Product Unit Size | Cost | Quantity | Stock |
|---|
CVT-313 is a potent and selective inhibitor of cyclin-dependent kinase 2 (CDK2).
| Cas No. | 199986-75-9 |
|---|---|
| Purity | ≥98% |
| Formula | C22H28N6O3 |
| Formula Wt. | 400.48 |
| IUPAC Name | 2,2'-({9-Isopropyl-6-[(4-methoxybenzyl)amino]-9H-purin-2-yl}imino)diethanol |
| Synonym | CVT313; Cdk2 Inhibitor III; Cyclin-dependent kinase 2 Inhibitor III |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Brooks E., Gray N., et al. CVT-313, a specific and potent inhibitor of CDK2 that prevents neointimal proliferation. J Biol Chem. 272(46):29207-11 (1997). PMID: 9360999.
Faber A., Chiles T. Inhibition of cyclin-dependent kinase-2 induces apoptosis in human diffuse large B-cell lymphomas. Cell Cycle. 6(23):2982-9 (2007). PMID: 18156799.
Inhibitor of tropomyosin kinase receptors TRKA,...
Azoxy compound
Macrolide antibiotic
AMPK activator, D1-4, 5-HT1A/2/3/6/7, M1-5 mACh...
K+ channel blocker, catecholamine release stimu...
SIRT1/2 inhibitor, indirect p53 activator.
Endogenous peptide; actin polymerization inhibi...
Endogenous amino acid, also found in meat, dair...
Inhibitor of EGFR.
Peptide; PAR1 agonist.
Oxidative phosphorylation inhibitor.
SERCA inhibitor.
Naphthodianthrone found in Hypericum; dopamine ...
CHK1 inhibitor.
Flavonoid found in various plant sources; matri...
CDK inhibitor.
FGFR inhibitor.
Shellfish toxin produced by dinoflagellates and...
Benzophenanthridine alkaloid found in various p...
Endogenous peptide hormone, involved in stress ...