• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Dapivirine

Dapivirine

Product ID D0261
Cas No. 244767-67-7
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $112.60 In stock
5 mg $245.10 In stock
25 mg $759.70 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Dapivirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that is currently in clinical trials as a prophylactic against HIV infection. In various models such as dendritic cells and T cells, dapivirine exhibits antiviral activity by suppressing viral replication.

Product Info

Cas No.

244767-67-7

Purity

≥98%

Formula

C20H19N5

Formula Wt.

329.41

IUPAC Name

4-{[4-(Mesitylamino)-2-pyrimidinyl]amino}benzonitrile

Synonym

TMC120, R147681

Solubility

0.2mg/ml in DMSO and 0.3 mg/ml in DMF, sparingly soluble in aqueous buffers

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

D0261 MSDS PDF

Info Sheet

D0261 Info Sheet PDF

Brochures

Antivirals Booklet

References

Devlin B, Nuttall J, Wilder S, et al. Development of dapivirine vaginal ring for HIV prevention. Antiviral Res. 2013 Dec;100 Suppl:S3-8. PMID: 24188702.

Gupta SK, Nutan. Clinical use of vaginal or rectally applied microbicides in patients suffering from HIV/AIDS. HIV AIDS (Auckl). 2013 Oct 22;5:295-307. PMID: 24174883.

Njai HF, Lewi PJ, Janssen CG, et al. Pre-incubation of cell-free HIV-1 group M isolates with non-nucleoside reverse transcriptase inhibitors blocks subsequent viral replication in co-cultures of dendritic cells and T cells. Antivir Ther. 2005;10(2):255-62. PMID: 15865220.

Van Herrewege Y, Michiels J, Van Roey J, et al. In vitro evaluation of nonnucleoside reverse transcriptase inhibitors UC-781 and TMC120-R147681 as human immunodeficiency virus microbicides. Antimicrob Agents Chemother. 2004 Jan;48(1):337-9. PMID: 14693562.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • A0964

    Adrenocorticotropic Hormone (1-13), human

    Endogenous peptide hormone fragment, involved i...

    ≥95%
  • S7061

    SRPIN340

    SRPK1 inhibitor.

    ≥98%
  • K1677

    Ketoprofen

    NSAID; COX-1/2 and lactate dehydrogenase inhibi...

    ≥98%
  • C002041

    Cabazitaxel

    Taxoid that disrupts the microtubular network i...

    ≥98%
  • P3568

    Pirarubicin

    Anthracycline, DNA intercalator; topoisomerase ...

    ≥98%
  • D5610

    Docosahexaenoic Acid (all cis-4,7,10,13,16,19)

    Essential fatty acid found in fish oil, involve...

    ≥98%
  • C017521

    Canagliflozin

    SGLT2 inhibitor

    ≥98%
  • A9912

    AZD-7762 Hydrochloride

    CHK1 inhibitor.

    ≥98%
  • A0910

    N-Acetyl-S-(N′-phenylthiocarbamoyl)-L-cysteine

    Cysteine-ITC conjugate, antioxidant.

    ≥98%
  • C9808

    CZC-54252

    LRRK2 inhibitor.

    ≥98%
  • C0267

    Carnosol

    Diterpene compound originally found in Rosmarin...

    ≥98%
  • A2244

    Aflatoxicol

    Mycotoxin, metabolite of aflatoxin B1 produced ...

    ≥98%
  • B1640

    Benzydamine Hydrochloride

    NSAID; PG synthetase inhibitor.

    ≥98%
  • A6002

    Apamin

    Peptide, bee venom toxin; SK2/3/4 K+ channel bl...

    ≥95%
  • E7357

    Esomeprazole Potassium

    (S) isomer of omeprazole; H+/K+ ATPase and MAO-...

    ≥98%
  • C0366

    Carvedilol Phosphate Hemihydrate

    FIASMA; α1- and β1/2-adrenergic antagonist.

    ≥98%
  • S7601

    Statil

    Aldose reductase inhibitor.

    ≥98%
  • B3573

    Bisdemethoxycurcumin

    Curcumin derivative; DNMT1 and α-amylase inhib...

    ≥98%
  • C1600

    Carcinoembryonic Antigen (605-613)

    Carcinoembryonic antigen epitope.

    ≥95%
  • S8046

    R-Sulforaphane, High Purity

    Naturally occuring isothiocyanate found in broc...

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only