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Dihydrokainic Acid

Dihydrokainic Acid

Product ID D3328
Cas No. 52497-36-6
Purity ≥98%
Product Unit SizeCostQuantityStock
10 mg $420.10 Please Inquire
25 mg $954.70 Please Inquire
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Dihydrokainic acid is an inhibitor of GLT-1, preventing cellular uptake of glutamate. Dihydrokainic acid exhibits neuromodulatory activity and may induce excitotoxicity and excessive NMDA receptor activation. In vivo, dihydrokainic acid attenuates binge drinking behavior.

Product Info

Cas No.

52497-36-6

Purity

≥98%

Formula

C10H17NO4

Formula Wt.

215.25

IUPAC Name

3-(carboxymethyl)-4-propan-2-ylpyrrolidine-2-carboxylic acid

Synonym

2-Carboxy-4-isopropyl-3-pyrrolidineacetic acid

Melting Point

285°C(dec.)

Solubility

Soluble in water (>110mg/mL).

Appearance

White Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

D3328 MSDS PDF

Info Sheet

D3328 Info Sheet PDF

References

Smith KL, John CS, Sypek EI, et al. Exploring the role of central astrocytic glutamate uptake in ethanol reward in mice. Alcohol Clin Exp Res. 2014 May;38(5):1307-14. PMID: 24655029.

Nie H, Weng HR. Impaired glial glutamate uptake induces extrasynaptic glutamate spillover in the spinal sensory synapses of neuropathic rats. J Neurophysiol. 2010 May;103(5):2570-80. PMID: 20220084.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
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