Description
Dolasetron is an antiemetic that is clinically used to prevent chemotherapy-induced nausea and emesis. Dolasetron acts as an antagonist at 5-HT3 receptors.
Product Unit Size | Cost | Quantity | Stock |
---|
Dolasetron is an antiemetic that is clinically used to prevent chemotherapy-induced nausea and emesis. Dolasetron acts as an antagonist at 5-HT3 receptors.
Cas No. | 115956-12-2 |
---|---|
Purity | ≥98% |
Formula | C19H20N2O3 |
Formula Wt. | 324.37 |
IUPAC Name | [(3S,7R)-10-oxo-8-azatricyclo[5.3.1.03,8]undecan-5-yl] 1H-indole-3-carboxylate |
Solubility | Soluble in water and ethanol. |
Appearance | White to off white powder |
Store Temp | Ambient |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Hsu ES. A review of granisetron, 5-hydroxytryptamine3 receptor antagonists, and other antiemetics. Am J Ther. 2010 Sep-Oct;17(5):476-86. PMID: 20844345.
Birmingham SD, Mecklenburg BW, Lujan E, et al. Dolasetron versus ondansetron as single-agent prophylaxis for patients at increased risk for postoperative nausea and vomiting: a prospective, double-blind, randomized trial. Mil Med. 2006 Sep;171(9):913-6. PMID: 17036618.
Carnitine derivative, involved in energy homeos...
CRM1/XPO1 inhibitor.
Terpene lactone found in Ginkgo.
Corticosteroid
ACE inhibitor.
Alkaloid found in Cephalotaxus; ribosomal prote...
Alkaloid compound found in Corydalis.
PI3K and PDK1 inhibitor.
Phosphodiesterase inhibitor that produces anti-...
Cholesterol ester transfer protein inhibitor.
Actinomycin derivative used to study apoptosis ...
Synthetic derivative of vasicine, mucolytic.
Endogenous peptide hormone, involved in cell gr...
Endogenous steroid hormone; ERβ, NMDA, σ1 ago...
Endogenous peptide fragment, involved in vasoco...
Indirect activator of STING signaling
2-methyl-1,4-naphthoquinone derivative
Peptide; NK2 antagonist.
Docetaxel impurity
JAK1/2/3 inhibitor.