Description
Dolasetron is an antiemetic that is clinically used to prevent chemotherapy-induced nausea and emesis. Dolasetron acts as an antagonist at 5-HT3 receptors.
| Product Unit Size | Cost | Quantity | Stock |
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Dolasetron is an antiemetic that is clinically used to prevent chemotherapy-induced nausea and emesis. Dolasetron acts as an antagonist at 5-HT3 receptors.
| Cas No. | 115956-12-2 |
|---|---|
| Purity | ≥98% |
| Formula | C19H20N2O3 |
| Formula Wt. | 324.37 |
| IUPAC Name | [(3S,7R)-10-oxo-8-azatricyclo[5.3.1.03,8]undecan-5-yl] 1H-indole-3-carboxylate |
| Solubility | Soluble in water and ethanol. |
| Appearance | White to off white powder |
| Store Temp | Ambient |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
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| Info Sheet |
Hsu ES. A review of granisetron, 5-hydroxytryptamine3 receptor antagonists, and other antiemetics. Am J Ther. 2010 Sep-Oct;17(5):476-86. PMID: 20844345.
Birmingham SD, Mecklenburg BW, Lujan E, et al. Dolasetron versus ondansetron as single-agent prophylaxis for patients at increased risk for postoperative nausea and vomiting: a prospective, double-blind, randomized trial. Mil Med. 2006 Sep;171(9):913-6. PMID: 17036618.
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