Description
Dolasetron is an antiemetic that is clinically used to prevent chemotherapy-induced nausea and emesis. Dolasetron acts as an antagonist at 5-HT3 receptors.
| Product Unit Size | Cost | Quantity | Stock |
|---|
Dolasetron is an antiemetic that is clinically used to prevent chemotherapy-induced nausea and emesis. Dolasetron acts as an antagonist at 5-HT3 receptors.
| Cas No. | 115956-12-2 |
|---|---|
| Purity | ≥98% |
| Formula | C19H20N2O3 |
| Formula Wt. | 324.37 |
| IUPAC Name | [(3S,7R)-10-oxo-8-azatricyclo[5.3.1.03,8]undecan-5-yl] 1H-indole-3-carboxylate |
| Solubility | Soluble in water and ethanol. |
| Appearance | White to off white powder |
| Store Temp | Ambient |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Hsu ES. A review of granisetron, 5-hydroxytryptamine3 receptor antagonists, and other antiemetics. Am J Ther. 2010 Sep-Oct;17(5):476-86. PMID: 20844345.
Birmingham SD, Mecklenburg BW, Lujan E, et al. Dolasetron versus ondansetron as single-agent prophylaxis for patients at increased risk for postoperative nausea and vomiting: a prospective, double-blind, randomized trial. Mil Med. 2006 Sep;171(9):913-6. PMID: 17036618.
BH3 mimetic; Bcl-2, Bxl-xl, Bcl-w inhibitor.
D2 and D4 dopamine receptor inhibitor.
MEK1/2 and ERK inhibitor.
Endogenous amino acid, forms disulfide bridges ...
Cephalomannine derivative found in Taxus; poten...
Stable salt form of hyperforin, a compound foun...
FIASMA, 5-HT1/2, M1-5 mAChR, α1-adrenergic, hi...
HDAC inhibitor.
p110α PI3K and mTOR inhibitor.
Mesalazine derivative, sulfa drug; sepiapterin ...
PKC activator, carcinogen.
Toxin produced by Canarthis vesicatoria; PP1/2A...
Potential p53 activator or SIRT2 inhibitor.
Juvenile insect hormone mimic.
c-MET and Ron inhibitor.
Pyrrolidone; NMDA and mGluR5 agonist, N-type an...
Cathepsin inhibitor.
Endogenous peptide, involved in paracrine and a...
Phallotoxin found in Amanita phalloides; microt...
Reversible DNMT1-selective inhibitor