Description
Dolasetron is an antiemetic that is clinically used to prevent chemotherapy-induced nausea and emesis. Dolasetron acts as an antagonist at 5-HT3 receptors.
Product Unit Size | Cost | Quantity | Stock |
---|
Dolasetron is an antiemetic that is clinically used to prevent chemotherapy-induced nausea and emesis. Dolasetron acts as an antagonist at 5-HT3 receptors.
Cas No. | 115956-12-2 |
---|---|
Purity | ≥98% |
Formula | C19H20N2O3 |
Formula Wt. | 324.37 |
IUPAC Name | [(3S,7R)-10-oxo-8-azatricyclo[5.3.1.03,8]undecan-5-yl] 1H-indole-3-carboxylate |
Solubility | Soluble in water and ethanol. |
Appearance | White to off white powder |
Store Temp | Ambient |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Hsu ES. A review of granisetron, 5-hydroxytryptamine3 receptor antagonists, and other antiemetics. Am J Ther. 2010 Sep-Oct;17(5):476-86. PMID: 20844345.
Birmingham SD, Mecklenburg BW, Lujan E, et al. Dolasetron versus ondansetron as single-agent prophylaxis for patients at increased risk for postoperative nausea and vomiting: a prospective, double-blind, randomized trial. Mil Med. 2006 Sep;171(9):913-6. PMID: 17036618.
Azoxanthone derivative; S100A12 and S100A13 inh...
Found in Astragalus membranaceus.
CRM1/XPO1 inhibitor.
Carbapenem β-lactam; penicillin binding protei...
mTOR inhibitor.
Staurosporine derivative; PKC and FLT3 inhibito...
Tretinoin analog; RARα/β/γ agonist.
Folic acid derivative
Quinolone alkaloid precursor of irinotecan, ori...
Triazole; 14-α demethylase inhibitor, Smo modu...
Notch inhibitor.
Nucleoside (deoxycytidine) analog; DNMT inhibit...
Steroid; glucocorticoid agonist.
14α-demethylase inhibitor.
Peptide used to measure in vitro calcineurin ac...
Steroidal jerveratrum alkaloid found in Veratru...
γ-Secretase inhibitor.
p110α PI3K inhibitor.
Read-through agent and nonsense mutation target...
Cannabinoid receptor 2 selective agonist.