Description
Dolasetron is an antiemetic that acts as an antagonist at 5-HT3 receptors. Dolasetron also exhibits analgesic activity, decreasing pain sensitivity in clinical subjects with fibromyalgia.
Dolasetron Mesylate Hydrate
Product ID D5747
Cas No. 878143-33-0
Purity ≥98%
| Product Unit Size | Cost | Quantity | Stock |
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Product Info
| Cas No. | 878143-33-0 |
|---|---|
| Purity | ≥98% |
| Formula | C19H20N2O3 • CH4O3S • xH2O |
| Formula Wt. | 420.48 |
| IUPAC Name | methanesulfonic acid;[(3S,7R)-10-oxo-8-azatricyclo[5.3.1.03,8]undecan-5-yl] 1H-indole-3-carboxylate;hydrate |
| Solubility | DMSO: ≥ 39 mg/mL H2O: >30 mg/mL |
| Appearance | White to off white powder |
Shipping and Storage
| Store Temp | Ambient |
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| Ship Temp | Ambient |
Downloads
| MSDS | |
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| Info Sheet |
References
Roberts SM, Bezinover DS, Janicki PK. Reappraisal of the role of dolasetron in prevention and treatment of nausea and vomiting associated with surgery or chemotherapy. Cancer Manag Res. 2012;4:67-73. PMID: 22427733.
Vergne-Salle P, Dufauret-Lombard C, Bonnet C, et al. A randomised, double-blind, placebo-controlled trial of dolasetron, a 5-hydroxytryptamine 3 receptor antagonist, in patients with fibromyalgia. Eur J Pain. 2011 May;15(5):509-14. PMID: 21036635.