LKT Labs

Biochemicals for Life Science Research

[DPhe7]-Bradykinin

[DPhe7]-Bradykinin

Product ID B6809
Cas No.
Purity ≥95%
Product Unit SizeCostQuantityStock
1 mg $65.00 In stock
2 mg $111.00 In stock
5 mg $196.00 In stock
Bulk Quote

Quicklinks

Description

Bradykinin is a peptide that exhibits natriuretic, antioxidative, vasodilatory, and pro-angiogenic activities. Bradykinin stimulates bradykinin receptors and increases PLC activity, decreasing ENaC open probability, inhibiting distal nephron Na+ transport, and inducing natriuresis. In vitro, bradykinin decreases H2O2-induced senescence, increases activity of superoxide dismutase (SOD), and suppresses DNA damage, ROS production, and NADPH oxidase activity. Additionally, bradykinin increases expression of VEGF and promotes tube formation in prostate cancer cells.

Product Info

Purity

≥95%
Formula

C54H75N15O11
Formula Wt.

1110.29
Solubility

Soluble in water.

Shipping and Storage

Store Temp

-20°C
Ship Temp

Ambient

Downloads

MSDS

B6809 MSDS PDF
Info Sheet

B6809 Info Sheet PDF

References

Mamenko M, Zaika O, Pochynyuk O. Direct regulation of ENaC by bradykinin in the distal nephron. Implications for renal sodium handling. Curr Opin Nephrol Hypertens. 2014 Mar;23(2):122-9. PMID: 24378775.

Yu HS, Wang SW, Chang AC, et al. Bradykinin promotes vascular endothelial growth factor expression and increases angiogenesis in human prostate cancer cells. Biochem Pharmacol. 2014 Jan 15;87(2):243-53. PMID: 24225154.

Dong R, Xu X, Li G, et al. Bradykinin inhibits oxidative stress-induced cardiomyocytes senescence via regulating redox state. PLoS One. 2013 Oct 25;8(10):e77034. PMID: 24204728.

Feher A, Cassuto J, Szabo A, et al. Increased tissue angiotensin-converting enzyme activity impairs bradykinin-induced dilation of coronary arterioles in obesity. Circ J. 2013;77(7):1867-76. PMID: 23603844.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • B4518

    Bleomycin Sulfate

    Mixture of glycopeptide bleomycin sulfate salts...

    ≥90%
  • K977545

    Kynurenic acid

    Endogenous NMDA receptor antagonist.

    ≥99%
  • C000171

    C-171

    STING inhibitor

    ≥98%
  • P1917

    Phenylethyl 3-methylcaffeate

    Derivative of methyl caffeate, hydroxycinnamic ...

    ≥97%
  • A7200

    AS-252424

    p110γ PI3K inhibitor, potential TRPC1/5/6 nega...

    ≥98%
  • M3377

    Mitomycin C

    Alkaloid produced by Streptomyces, DNA cross-li...

    ≥98%
  • H1794

    Hexamethonium Bromide Hydrate

    Non-depolarizing NMJ blocker; nAChR antagonist....

    ≥98%
  • A5217

    trans-Anethole

    Phenylpropene derivative found in essential oil...

    ≥98%
  • R3014

    Recombinant TpN 47 protein

    Recombinant protein containing Treponema pallid...

    ≥95%
  • G4434

    Gliotoxin

    Toxin produced by Aspergillus.

    ≥98%
  • N7604

    Naltriben

    δ2OR antagonist.

    ≥95%
  • M1626

    Megestrol Acetate

    Synthetic progestogen, orexigenic.

    ≥98%
  • D1643

    Delta Sleep Inducing Peptide

    Peptide; GABA potentiator, NMDA negative allost...

    ≥95%
  • S9775

    Systemin

    Peptide hormone found in Solanaceae family plan...

    ≥95%
  • L0254

    Lansoprazole

    H+/K+ ATPase inhibitor.

    ≥98%
  • P3018

    Phellodendrine

    Quaternary base alkaloid found in Phellodendron...

    ≥98%
  • E6245

    Eplerenone

    Mineralocorticoid antagonist.

    ≥99%
  • F3207

    Fibronectin CS-1 Peptide

    Peptide; α4β1 integrin activator.

    ≥95%
  • E543721

    Ensartinib

    A third-generation ALK inhibitor.

    ≥98%
  • R1806

    Rebamipide

    Quinolone, antioxidant.

    ≥98%