LKT Labs

Biochemicals for Life Science Research

[DPhe7]-Bradykinin

[DPhe7]-Bradykinin

Product ID B6809
Cas No.
Purity ≥95%
Product Unit SizeCostQuantityStock
1 mg $65.40 In stock
2 mg $110.50 In stock
5 mg $196.20 In stock
Bulk Quote

Quicklinks

Description

Bradykinin is a peptide that exhibits natriuretic, antioxidative, vasodilatory, and pro-angiogenic activities. Bradykinin stimulates bradykinin receptors and increases PLC activity, decreasing ENaC open probability, inhibiting distal nephron Na+ transport, and inducing natriuresis. In vitro, bradykinin decreases H2O2-induced senescence, increases activity of superoxide dismutase (SOD), and suppresses DNA damage, ROS production, and NADPH oxidase activity. Additionally, bradykinin increases expression of VEGF and promotes tube formation in prostate cancer cells.

Product Info

Purity

≥95%
Formula

C54H75N15O11
Formula Wt.

1110.29
Solubility

Soluble in water.

Shipping and Storage

Store Temp

-20°C
Ship Temp

Ambient

Downloads

MSDS

B6809 MSDS PDF
Info Sheet

B6809 Info Sheet PDF

References

Mamenko M, Zaika O, Pochynyuk O. Direct regulation of ENaC by bradykinin in the distal nephron. Implications for renal sodium handling. Curr Opin Nephrol Hypertens. 2014 Mar;23(2):122-9. PMID: 24378775.

Yu HS, Wang SW, Chang AC, et al. Bradykinin promotes vascular endothelial growth factor expression and increases angiogenesis in human prostate cancer cells. Biochem Pharmacol. 2014 Jan 15;87(2):243-53. PMID: 24225154.

Dong R, Xu X, Li G, et al. Bradykinin inhibits oxidative stress-induced cardiomyocytes senescence via regulating redox state. PLoS One. 2013 Oct 25;8(10):e77034. PMID: 24204728.

Feher A, Cassuto J, Szabo A, et al. Increased tissue angiotensin-converting enzyme activity impairs bradykinin-induced dilation of coronary arterioles in obesity. Circ J. 2013;77(7):1867-76. PMID: 23603844.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • S1059

    Scopolamine Hydrobromide Trihydrate

    Tropane alkaloid found in Solanaceae plants; M1...

    ≥98%
  • H966144

    6-Hydroxydopamine Hydrobromide

    Neurotoxin frequently used to aid in modeling P...

    ≥98%
  • A2500

    AG-1478

    EGFR inhibitor.

    ≥98%
  • P1200

    PD-184352

    MEK1/2 and Raf inhibitor.

    ≥98%
  • G7442

    GSK-343

    EZH2 HMT inhibitor.

    ≥98%
  • B6805

    Bradykinin (1-7)

    Natriuretic, vasodilatory peptide fragment; B1/...

    ≥95%
  • M1687

    Mevinolin

    Statin, naturally produced by mushrooms; HMG-Co...

    ≥97%
  • C2945

    Chlorophyllin Sodium-Copper Salt

    Semi-synthetic derivative of chlorophyll; food ...

    USP 28
  • R2516

    RGES

    Peptide, used as control to measure RGDS peptid...

    ≥95%
  • S1872

    Sesamin

    Lignin found in Sesamin indicum;

    ≥98%
  • R5974

    Rosuvastatin Calcium

    Statin; HMG-CoA reductase inhibitor, potential ...

    ≥98%
  • A9600

    AZD-3463

    ALK and IGF-1R inhibitor.

    ≥99%
  • E537332

    Enniatin A

    Mycotoxin contaminant found in cereal grains.

    ≥98%
  • D1760

    3-Acetyl-deoxynivalenol

    Type A trichothecene mycotoxin produced by Fusa...

    ≥98%
  • E5211

    Endomorphin-2

    Endogenous opioid peptide; μOR agonist.

    ≥95%
  • T3034

    Thienylethyl Isothiocyanate

    Thienylbutyl ITC analog.

    ≥98%
  • L1852

    Lenalidomide

    Thalidomide derivative; cereblon and TNF-α inh...

    ≥98%
  • S336486

    Simeprevir

    NS3/4A inhibitor

    ≥99%
  • D1769

    Dermorphin

    Opioid peptide; μOR agonist.

    ≥96%
  • C0148

    Calcitonin, human

    Endogenous neuropeptide hormone, lowers extrace...

    ≥95%