• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Echinacoside

Echinacoside

Product ID E0929
Cas No. 82854-37-3
Purity ≥98%
Product Unit SizeCostQuantityStock
5 mg $102.00 In stock
10 mg $159.40 In stock
25 mg $296.30 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Echinacoside is a phenylethanoid glycoside found in Echinacea, among other sources; it exhibits neuroprotective and vasodilatory activities. In vivo, echinacoside inhibits cytochrome c release and caspase-3 activation through modulation of ERK signaling, resulting in neuroprotection in a model of middle cerebral artery occlusion. Echinacoside also displays neuroprotective benefit in a MTPT-induced mouse model of Parkinson’s Disease, decreasing the Bax/Bcl-2 ratio and inhibiting suppression of dopamine and dopamine transporter (DAT) levels. This compound increases cGMP in rat aortic rings, inducing vasodilation. Additionally, echinacoside improves bone mineral density and microarchitecture, decreasing RANKL expression and increasing esteoprotegerin levels in animal models of osteopenia.

Product Info

Cas No.

82854-37-3

Purity

≥98%

Formula

C35H46O20

Formula Wt.

786.73

Chemical Name

[(2R,3R,4R,5R,6R)-6-[2-(3,4-dihydroxyphenyl)ethoxy]-5-hydroxy-2-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl] (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate

IUPAC Name

[(2R,3R,4R,5R,6R)-6-[2-(3,4-dihydroxyphenyl)ethoxy]-5-hydroxy-2-[[(2R, 3R,4S,5S,6R)-3,4, 5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]-4-[(2S,3R,4R,5R, 6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl] (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate

Solubility

Soluble in water and ethanol.

Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

E0929 MSDS PDF

Info Sheet

E0929 Info Sheet PDF

References

Yang X, Li F, Yang Y, et al. Efficacy and safety of echinacoside in a rat osteopenia model. Evid Based Complement Alternat Med. 2013;2013:926928. PMID: 23573159.

Zhu M, Lu C, Li W. Transient exposure to echinacoside is sufficient to activate Trk signaling and protect neuronal cells from rotenone. J Neurochem. 2013 Feb;124(4):571-80. PMID: 23189969.

Wei LL, Chen H, Jiang Y, et al. Effects of echinacoside on histio-central levels of active mass in middle cerebral artery occlusion rats. Biomed Environ Sci. 2012 Apr;25(2):238-44.PMID: 22998833.

Zhao Q, Gao J, Li W, et al. Neurotrophic and neurorescue effects of Echinacoside in the subacute MPTP mouse model of Parkinson's disease. Brain Res. 2010 Jul 30;1346:224-36. PMID: 20478277.

He WJ, Fang TH, Ma X, et al. Echinacoside elicits endothelium-dependent relaxation in rat aortic rings via an NO-cGMP pathway. Planta Med. 2009 Oct;75(13):1400-4. PMID: 19468974.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • F8250

    Fumitremorgin C

    Mycotoxin found in Aspergillus and Penicillum; ...

    ≥98%
  • G2969

    Growth Hormone Releasing Hexapeptide

    Synthetic peptide hormone, met-enkephalin analo...

    ≥95%
  • T7134

    trans-3,4′,5-Trimethoxy Stilbene

    Resveratrol prodrug; potential SIRT1 activator....

    ≥99%
  • S8046

    R-Sulforaphane, High Purity

    Naturally occuring isothiocyanate found in broc...

    ≥98%
  • D1644

    Deltorphin I

    Opioid peptide; δOR agonist.

    ≥98%
  • N4524

    NLG919

    Indoleamine-2,3-dioxygenase inhibitor.

    ≥98%
  • O9398

    Oxymetazoline Hydrochloride

    Imidazoline derivative; α1-adrenergic agonist,...

    ≥98%
  • B1668

    Berteroin

    Thio sulforaphane analog, ITC.

    ≥97%
  • N5768

    Norfloxacin

    Fluoroquinolone; topoisomerase IV and bacterial...

    ≥98%
  • A001001

    A 83-01

    TGFbeta receptor inhibitor

    ≥98%
  • A2658

    Agomelatine

    Melatonin analog; MT1/2 agonist, 5-HT2C antagon...

    ≥98%
  • S3368

    S1RA

    σ1 antagonist.

    ≥99%
  • R2917

    Rhein

    Diacerein metabolite, anthraquinone found in Rh...

    ≥88%
  • A0958

    Aconitine

    Toxin found in Aconitum; voltage-gated Na+ chan...

    ≥95%
  • R0248

    Ramatroban

    CRTH2 inhibitor, TxA2 antagonist.

    ≥98%
  • E0003

    E64-d

    Cathepsin inhibitor.

    ≥97%
  • S9754

    Syntide 2

    Synthetic peptide, CDPK, PKC, CaMKII substrate....

    ≥95%
  • K0652

    Kb NB 142-70

    PKD inhibitor.

    ≥98%
  • P8169

    Purpurin

    Anthraquinone pigment found in madder root; O-a...

    ≥90%
  • M3598

    Mizoribine Hydrobromide

    IMPDH inhibitor.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only