• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Efavirenz

Efavirenz

Product ID E2003
Cas No. 154598-52-4
Purity ≥99%
Product Unit SizeCostQuantityStock
5 mg $68.30 In stock
10 mg $89.30 In stock
25 mg $152.30 In stock
50 mg $236.30 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Efavirenz is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that exhibits antiviral and anticancer activities. Efavirenz is clinically used to treat HIV infection; it induces autophagy in neurons, leading to some centrally mediated toxicity. In various cancer cell lines, efavirenz inhibits cellular proliferation and increases activation of p53.

Product Info

Cas No.

154598-52-4

Purity

≥99%

Formula

C14H9ClF3NO2

Formula Wt.

315.67

IUPAC Name

(4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one

Melting Point

139-141°C

Solubility

Ethanol (20 mg/ml), DMF (20 mg/ml), DMSO (14 mg/ml)

Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

E2003 MSDS PDF

Info Sheet

E2003 Info Sheet PDF

Brochures

Antivirals Booklet

References

Schauer GD, Huber KD, Leuba SH, et al. Mechanism of allosteric inhibition of HIV-1 reverse transcriptase revealed by single-molecule and ensemble fluorescence. Nucleic Acids Res. 2015 Feb 1;42(18):11687-96. PMID: 25232099.

Purnell PR, Fox HS. Efavirenz induces neuronal autophagy and mitochondrial alterations. J Pharmacol Exp Ther. 2014 Nov;351(2):250-8. PMID: 25161171.

Hecht M, Harrer T, Büttner M, et al. Cytotoxic effect of efavirenz is selective against cancer cells and associated with the cannabinoid system. AIDS. 2013 Aug 24;27(13):2031-40. PMID: 23612009.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • K0053

    Kanamycin A Monosulfate

    Aminoglycoside; protein translation inhibitor, ...

    ≥98%
  • O4556

    Olomoucine

    Purine derivative; CDK inhibitor.

    ≥98%
  • I5203

    Inauhzin

    p53 activator, IMPDH and SIRT1 inhibitor.

    ≥98%
  • T8153

    Tunicamycin

    Nucleoside antibiotic mixture; GlcNAc phosphotr...

    ≥98%
  • A6978

    Artemisinin

    Sesquiterpene lactone found in Artemisia (wormw...

    ≥98%
  • B1973

    Besifloxacin Hydrochloride

    Fluoroquinolone; topoisomerase IV and bacterial...

    ≥98%
  • A4675

    Alternariol

    Mycotoxin produced by Alternaria; topoisomerase...

    ≥98%
  • I5313

    Indinavir Sulfate

    HIV protease, GLUT4, calpain inhibitor.

    ≥99%
  • F7657

    Ftorafur

    5-fluorouracil prodrug, pyrimidine analog; thym...

    ≥99%
  • G7345

    GSK-2606414

    PERK inhibitor.

    ≥99%
  • Q8134

    Quinapril Hydrochloride

    ACE inhibitor.

    ≥98%
  • A6979

    Dihydroartemisinin

    Sesquiterpene lactone derived from Artemesia; m...

    ≥96%
  • C0172

    Carbimazole

    Methimazole prodrug; thyroid peroxidase inhibit...

    ≥98%
  • A4847

    Amylin, human

    Endogenous peptide hormone inolved in gastric e...

    ≥95%
  • T1014

    7-TES-Paclitaxel

    Synthesis impurity

    ≥95%
  • C1869

    Cerulenin

    Found in Cephalosporium; fatty acid synthase in...

    ≥98%
  • H000051

    H-151

    STING antagonist

    ≥99%
  • B3272

    Bis(3,5-dibromosalicyl) Fumarate

    Aspirin analog; hemoglobin chain cross-linker.<...

    ≥91%
  • T3468

    Tirapazamine

    Topoisomerase II inhibitor, RPA modulator.

    ≥98%
  • G3458

    Ginsenoside Rg1

    Triterpene saponin found in species of Panax.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only