LKT Labs

Biochemicals for Life Science Research

Enniatin B1

Product ID E537335
Cas No. 19914-20-6
Purity ≥99%
Product Unit SizeCostQuantityStock
1 mg $231.50 In stock
5 mg $868.20 In stock
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Description

Enniatins are a group of mycotoxins produced by several fungal species. They are cyclic hexadepsipeptides structurally related to beauvericin. They may be found as contaminants in food commodities, particularly in cereal grains. Enniatins are found to have a variety of biological activities including insecticidal, antifungal, antibiotic and cytotoxic properties. They have been shown to induce apoptosis in several human cancer cell lines and are gaining interest as potential anticancer drugs.

Product Info

Cas No.

19914-20-6
Purity

≥99%
Formula

C34H59N3O9
Formula Wt.

653.86
Chemical Name

3-butan-2-yl-4,10,16-trimethyl-6,9,12,15,18-penta(propan-2-yl)-1,7,13-trioxa-4,10,16-triazacyclooctadecane-2,5,8,11,14,17-hexone
IUPAC Name

(3S,6R,9S,12R,15S,18R)-3-[(2S)-2-Butanyl]-6,9,12,15,18-pentaisopropyl-4,10,16-trimethyl-1,7,13-trioxa-4,10,16-triazacyclooctadecane-2,5,8,11,14,17-hexone
Synonym

Enniatin B1
Solubility

Soluble in DMSO, ethanol, methanol and DMF. Insoluble in water.

Shipping and Storage

Store Temp

-20°C
Ship Temp

Ambient

Downloads

MSDS

E537335 MSDS PDF
Info Sheet

E537335 Info Sheet PDF

References

Liuzzi VC, Mirabelli V, Cimmarusti MT, et al. Enniatin and beauvericin biosynthesis in Fusarium species: production profiles and structural determinant prediction. Toxins (Basel). 2017 Feb;9(2):45. PMID: 28125067.

Gunter AB, Hermans A, Bosnich W, et al. Protein engineering of Saccharomyces cerevisiae transporter Pdr5p identifies key residues that impact Fusarium mycotoxin export and resistance to inhibition. Microbiologyopen. 2016 Dec;5(6):979-991. PMID: 27263049.

Nazari F, Sulyok M, Kobarfard F, et al. Evaluation of emerging mycotoxins beauvericin, enniatins, fusaproliferin and moniliformin in domestic rice in Iran. Iran J Pharm Res. 2015 Spring;14(2):505-512. PMID: 25901158.

Dornetshuber-Fleiss R, Heilos D, Mohr T, et al. The naturally born fusariotoxin enniatin B and sorafenib exert synergistic activity against cervical cancer in vitro and in vivo. Biochem Pharmacol. 2015 Feb 1;93(3):318-331. PMID: 25557295.

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