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Erythromycin Ethylsuccinate

Erythromycin Ethylsuccinate

Product ID E6995
Cas No. 41342-53-4
Purity ≥97%
Product Unit SizeCostQuantityStock
5 g $71.50 In stock
25 g $204.30 In stock
100 g $385.90 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Erythromycin is a macrolide antibiotic that binds the 50s subunit of bacterial ribosomes, inhibiting protein synthesis by preventing transfer of tRNA from the A site to the P site. This compound displays antibacterial activity against both gram positive and gram negative bacteria; it also inhibits mammalian mRNA splicing.

Product Info

Cas No.

41342-53-4

Purity

≥97%

Formula

C43H75NO16

Formula Wt.

862.05

Chemical Name

Anamycin

IUPAC Name

4-O-[(2R,3S,4R,6S)-4-(dimethylamino)-2-[[(3R,4S,5S,6R,7R,9R,11R,12R,13S, 14R)-14-ethyl-7,12,13-trihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4, 6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-2, 10-dioxo-oxacyclotetradec-6-yl]oxy]-6-methyloxan-3-yl] 1-O-ethyl butanedioate

Synonym

E.E.S., Arpimycin, Durapaediat, E-Mycin E, Eryliquid, Eryped.

Melting Point

109-110°C

Solubility

Very slightly soluble in water. Soluble in acetone (500 mg/L), methanol (250 mg/mL), or ethanol (110 mg/mL).

Appearance

White crystalline powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

E6995 MSDS PDF

Info Sheet

E6995 Info Sheet PDF

References

Hertweck M, Hiller R, Mueller MW. Inhibition of nuclear pre-mRNA splicing by antibiotics in vitro. Eur J Biochem. 2002 Jan;269(1):175-83. PMID: 11784311.

Menninger JR, Otto DP. Erythromycin, carbomycin, and spiramycin inhibit protein synthesis by stimulating the dissociation of peptidyl-tRNA from ribosomes. Antimicrob Agents Chemother. 1982 May;21(5):811-8. PMID: 6179465.

Custom Order

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