Description
Fexofenadine is a second-generation histamine H1 receptor antagonist. Fexofenadine exhibits antihistamine activity and is clinically used to treat seasonal allergic rhinitis.
| Product Unit Size | Cost | Quantity | Stock |
|---|
Fexofenadine is a second-generation histamine H1 receptor antagonist. Fexofenadine exhibits antihistamine activity and is clinically used to treat seasonal allergic rhinitis.
| Cas No. | 153439-40-8 |
|---|---|
| Purity | ≥98% |
| Formula | C32H39NO4 • HCl |
| Formula Wt. | 538.12 |
| IUPAC Name | 2-[4-[1-hydroxy-4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]butyl] phenyl]-2-methylpropanoic acid;hydrochloride |
| Synonym | Allegra, Telfast |
| Melting Point | 148-150°C |
| Solubility | DMSO to 50 mM, water to 2 mg/mL, ethanol to 107 mg/mL, methanol |
| Appearance | A White Crystalline Powder |
| Store Temp | 4°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Compalati E, Baena-Cagnani R, Penagos M, et al. Systematic review on the efficacy of fexofenadine in seasonal allergic rhinitis: a meta-analysis of randomized, double-blind, placebo-controlled clinical trials. Int Arch Allergy Immunol. 2011;156(1):1-15. PMID: 21969990.
Smith SM, Gums JG. Fexofenadine: biochemical, pharmacokinetic and pharmacodynamic properties and its unique role in allergic disorders. Expert Opin Drug Metab Toxicol. 2009 Jul;5(7):813-22. PMID: 19545214.
Antimuscarinic
DPP4 inhibitor.
Saponin found in Dioscorea; Na+/K+ ATPase and C...
Sesquiterpene lactone found in Saussurea.
Mycotoxin produced by species of Aspergillus; D...
Flavonoid glycoside found in Pyrola.
NSAID; COX-1/2 inhibitor.
Indole found in cruciferous vegetables; AhR ago...
Steroid; glucocorticoid agonist.
Triterpene saponin found in species of Panax. <...
Methimazole prodrug; thyroid peroxidase inhibit...
Derivative of methyl caffeate, hydroxycinnamic ...
Broad-spectrum antibiotic
Peptide found in amphibian skin; GRP (BB1) and ...
Synthetic peptice; μOR agonist.
EGFR (WT, T790M) inhibitor.
Endogenous heptapeptide; P2X3 and N-formylpepti...
Tyrosine kinase inhibitor.
TxA2 synthase inhibitor.
Coumarin, more potent isomer; VKORC1 inhibitor....