Description
Fexofenadine is a second-generation histamine H1 receptor antagonist. Fexofenadine exhibits antihistamine activity and is clinically used to treat seasonal allergic rhinitis.
| Product Unit Size | Cost | Quantity | Stock |
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Fexofenadine is a second-generation histamine H1 receptor antagonist. Fexofenadine exhibits antihistamine activity and is clinically used to treat seasonal allergic rhinitis.
| Cas No. | 153439-40-8 |
|---|---|
| Purity | ≥98% |
| Formula | C32H39NO4 • HCl |
| Formula Wt. | 538.12 |
| IUPAC Name | 2-[4-[1-hydroxy-4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]butyl] phenyl]-2-methylpropanoic acid;hydrochloride |
| Synonym | Allegra, Telfast |
| Melting Point | 148-150°C |
| Solubility | DMSO to 50 mM, water to 2 mg/mL, ethanol to 107 mg/mL, methanol |
| Appearance | A White Crystalline Powder |
| Store Temp | 4°C |
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| Ship Temp | Ambient |
| MSDS | |
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| Info Sheet |
Compalati E, Baena-Cagnani R, Penagos M, et al. Systematic review on the efficacy of fexofenadine in seasonal allergic rhinitis: a meta-analysis of randomized, double-blind, placebo-controlled clinical trials. Int Arch Allergy Immunol. 2011;156(1):1-15. PMID: 21969990.
Smith SM, Gums JG. Fexofenadine: biochemical, pharmacokinetic and pharmacodynamic properties and its unique role in allergic disorders. Expert Opin Drug Metab Toxicol. 2009 Jul;5(7):813-22. PMID: 19545214.
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