LKT Labs

Biochemicals for Life Science Research

Fibronectin CS-1 Peptide

Fibronectin CS-1 Peptide

Product ID F3207
Cas No.
Purity ≥95%
Product Unit SizeCostQuantityStock
1 mg $52.50 In stock
2 mg $94.50 In stock
5 mg $183.80 In stock
Bulk Quote

Quicklinks

Description

Fibronectin CS-1 peptide binds α4β1 integrin; it exhibits pro-metastatic and immunomodulatory activities. Fibronectin CS-1 peptide is involved in oral squamous cell carcinoma pathogenesis, regulating migration and invasion. This peptide may increase expression of matrix metalloproteinases (MMPs). In vitro, fibronectin CS-1 peptide stimulates proliferation of T cells. In animal models of cerebral ischemia/reperfusion, fibronectin CS-1 peptide decreases leukocyte infiltration in lesioned areas, decreasing infarct size.

Product Info

Purity

≥95%
Formula

C38H64N8O15
Formula Wt.

872.97
Synonym

Fibronectin CS1
Solubility

Soluble in water.

Appearance

White to off-white powder

Shipping and Storage

Store Temp

-20°C
Ship Temp

Ambient

Downloads

Info Sheet

F3207 Info Sheet PDF

References

Kamarajan P, Garcia-Pardo A, D'Silva NJ, et al. The CS1 segment of fibronectin is involved in human OSCC pathogenesis by mediating OSCC cell spreading, migration, and invasion. BMC Cancer. 2010 Jun 25;10:330. PMID: 20579373.

Yakubenko VP, Lobb RR, Plow EF, et al. Differential induction of gelatinase B (MMP-9) and gelatinase A (MMP-2) in T lymphocytes upon alpha(4)beta(1)-mediated adhesion to VCAM-1 and the CS-1 peptide of fibronectin. Exp Cell Res. 2000 Oct 10;260(1):73-84. PMID: 11010812.

Lehnert K, Print CG, Yang Y, et al. MAdCAM-1 costimulates T cell proliferation exclusively through integrin alpha4beta7, whereas VCAM-1 and CS-1 peptide use alpha4beta1: evidence for "remote" costimulation and induction of hyperresponsiveness to B7 molecules. Eur J Immunol. 1998 Nov;28(11):3605-15. PMID: 9842903.

Yanaka K, Camarata PJ, Spellman SR, et al. Neuronal protection from cerebral ischemia by synthetic fibronectin peptides to leukocyte adhesion molecules. J Cereb Blood Flow Metab. 1996 Nov;16(6):1120-5. PMID: 8898683.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • I7659

    1-Isothiocyanato-8-(methylsulfonyl)-octane

    ITC, erysolin analog.

    ≥98%
  • S0501

    SB-939

    HDAC inhibitor.

    ≥98%
  • P3210

    Picoplatin

    Pt-based DNA cross-linker.

    ≥98%
  • R1724

    Regadenoson

    Adenosine A2A agonist.

    ≥99%
  • T1778

    2,3,5,6-Tetramethylpyrazine

    Dihydropyrazine found in Ligusticum walliichi. ...

    ≥98%
  • T6830

    Triadimefon

    Neurotoxin, mutagen.

    ≥98%
  • P6818

    Prednisolone

    Cortisol derivative; glucocorticoid agonist.

    ≥98%
  • A4802

    Amantadine Hydrochloride

    Viral M2 proton channel blocker, MAO-A, NET, NM...

    ≥98%
  • A724092

    Asciminib Hydrochloride

    Allosteric inhibitor

    ≥98%
  • N7332

    NSI-189

    Stem cell neurogenesis inducer.

    ≥99%
  • Y4802

    YM-201636

    PIKfyve inhibitor.

    ≥98%
  • V5886

    Voriconazole

    Triazole; 14α demethylase inhibitor.

    ≥98%
  • B8174

    Butylated Hydroxyanisole

    Commercial food additive, antioxidant.

    ≥96%
  • A5056

    Amorolfine Hydrochloride

    14α-demethylase inhibitor.

    ≥98.5%
  • A7668

    Atracurium Besylate

    Non-depolarizing NMJ blocker; AChR antagonist.<...

    ≥95%
  • A9914

    AZD-8055

    mTOR inhibitor.

    ≥98%
  • T7034

    Trimethoprim

    Dihydrofolate reductase inhibitor.

    ≥98%
  • C2960

    Chondroitin Sulfate, cow

    Polyanionic sulfated glycosaminoglycan, encogen...

    ≥90%
  • H0003

    H89

    PKA inhibitor, potential ROCK, S6K1, MSK1, PKB ...

    ≥98%
  • G4484

    Glucagon-like Peptide II, rat

    Endogenous peptide hormone, involved in intesti...

    ≥95%