Fibronectin CS-1 Peptide

Name: Fibronectin CS-1 Peptide
SKU: F3207
Availability: InStock

Product ID F3207

Cas No.

Purity ≥95%

Product Unit Size	Cost	Quantity		Stock

Bulk Quote

Quicklinks

Description
Product Info
Shipping and Storage
Downloads
References

Description

Fibronectin CS-1 peptide binds α4β1 integrin; it exhibits pro-metastatic and immunomodulatory activities. Fibronectin CS-1 peptide is involved in oral squamous cell carcinoma pathogenesis, regulating migration and invasion. This peptide may increase expression of matrix metalloproteinases (MMPs). In vitro, fibronectin CS-1 peptide stimulates proliferation of T cells. In animal models of cerebral ischemia/reperfusion, fibronectin CS-1 peptide decreases leukocyte infiltration in lesioned areas, decreasing infarct size.

Product Info

Purity	≥95%
Formula	C₃₈H₆₄N₈O₁₅
Formula Wt.	872.97
Synonym	Fibronectin CS1
Solubility	Soluble in water.
Appearance	White to off-white powder

Shipping and Storage

Store Temp	-20°C
Ship Temp	Ambient

Downloads

Info Sheet	F3207 Info Sheet PDF

References

Kamarajan P, Garcia-Pardo A, D'Silva NJ, et al. The CS1 segment of fibronectin is involved in human OSCC pathogenesis by mediating OSCC cell spreading, migration, and invasion. BMC Cancer. 2010 Jun 25;10:330. PMID: 20579373.

Yakubenko VP, Lobb RR, Plow EF, et al. Differential induction of gelatinase B (MMP-9) and gelatinase A (MMP-2) in T lymphocytes upon alpha(4)beta(1)-mediated adhesion to VCAM-1 and the CS-1 peptide of fibronectin. Exp Cell Res. 2000 Oct 10;260(1):73-84. PMID: 11010812.

Lehnert K, Print CG, Yang Y, et al. MAdCAM-1 costimulates T cell proliferation exclusively through integrin alpha4beta7, whereas VCAM-1 and CS-1 peptide use alpha4beta1: evidence for "remote" costimulation and induction of hyperresponsiveness to B7 molecules. Eur J Immunol. 1998 Nov;28(11):3605-15. PMID: 9842903.

Yanaka K, Camarata PJ, Spellman SR, et al. Neuronal protection from cerebral ischemia by synthetic fibronectin peptides to leukocyte adhesion molecules. J Cereb Blood Flow Metab. 1996 Nov;16(6):1120-5. PMID: 8898683.

Custom Order

Name*
First Last
Company/Institution
Email*
Enter Email Confirm Email
Product ID
Product Name
Unit Size
Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
Unit Label
Quantity
Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
Comments
Phone
This field is for validation purposes and should be left unchanged.

Fibronectin CS-1 Peptide

Quicklinks

Description

Product Info

Shipping and Storage

Downloads

References

Custom Order

Related Products

L-Thyroxine Sodium Pentahydrate

2-Carbomethoxy-3-thiophenesulfonyl Chloride

Harringtonine

S-Trityl-L-cysteine

Rufloxacin Hydrochloride

Hypaconitine

PX-866

R-(−)-Iberin

Clofazimine

Purvalanol A

L-(+)-Ascorbic Acid

RITA

S,S-(+)-Tetrandrine

Allopurinol

10,11-Dehydrocurvularin

LDK378

Isoimperatorin

R,S-Sulforaphane, Research Grade

KT5823

Calphostin C

Footer