LKT Labs

Biochemicals for Life Science Research

Fibronectin CS-1 Peptide

Product ID F3207
Cas No.
Purity ≥95%
Product Unit SizeCostQuantityStock
1 mg $50.00 In stock
2 mg $90.00 In stock
5 mg $175.00 In stock
Bulk Quote

Quicklinks

Description

Fibronectin CS-1 peptide binds α4β1 integrin; it exhibits pro-metastatic and immunomodulatory activities. Fibronectin CS-1 peptide is involved in oral squamous cell carcinoma pathogenesis, regulating migration and invasion. This peptide may increase expression of matrix metalloproteinases (MMPs). In vitro, fibronectin CS-1 peptide stimulates proliferation of T cells. In animal models of cerebral ischemia/reperfusion, fibronectin CS-1 peptide decreases leukocyte infiltration in lesioned areas, decreasing infarct size.

Product Info

Purity

≥95%
Formula

C38H64N8O15
Formula Wt.

872.97
Synonym

Fibronectin CS1
Solubility

Soluble in water.

Appearance

White to off-white powder

Shipping and Storage

Store Temp

-20°C
Ship Temp

Ambient

Downloads

Info Sheet

F3207 Info Sheet PDF

References

Kamarajan P, Garcia-Pardo A, D'Silva NJ, et al. The CS1 segment of fibronectin is involved in human OSCC pathogenesis by mediating OSCC cell spreading, migration, and invasion. BMC Cancer. 2010 Jun 25;10:330. PMID: 20579373.

Yakubenko VP, Lobb RR, Plow EF, et al. Differential induction of gelatinase B (MMP-9) and gelatinase A (MMP-2) in T lymphocytes upon alpha(4)beta(1)-mediated adhesion to VCAM-1 and the CS-1 peptide of fibronectin. Exp Cell Res. 2000 Oct 10;260(1):73-84. PMID: 11010812.

Lehnert K, Print CG, Yang Y, et al. MAdCAM-1 costimulates T cell proliferation exclusively through integrin alpha4beta7, whereas VCAM-1 and CS-1 peptide use alpha4beta1: evidence for "remote" costimulation and induction of hyperresponsiveness to B7 molecules. Eur J Immunol. 1998 Nov;28(11):3605-15. PMID: 9842903.

Yanaka K, Camarata PJ, Spellman SR, et al. Neuronal protection from cerebral ischemia by synthetic fibronectin peptides to leukocyte adhesion molecules. J Cereb Blood Flow Metab. 1996 Nov;16(6):1120-5. PMID: 8898683.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • SB5776

    Snake venom – Bothrops alternatus (urutu)

    Snake venom found in Bothrops alternatus urutu....

    ≥98%
  • N3584

    Nivalenol

    Trichothecene mycotoxin produced by Fusarium; p...

    ≥99%, TLC
  • O2145

    Ofloxacin Hydrochloride

    Fluoroquinolone; topoisomerase IV and bacterial...

    ≥98%
  • M1335

    Mdivi-1

    Quinazolinone; mitochondrial division inhibitor...

    ≥98%
  • I4802

    Imatinib Mesylate

    Abl, c-Kit, PDGFR inhibitor.

    ≥98%
  • T1679

    Tetracycline Hydrochloride

    Polyketide; protein translation inhibitor, mamm...

    ≥95%
  • L0209

    Lactoferrin, cow

    Endogenous glycoprotein; lactoferrin agonist.

    ≥92%
  • M0368

    Marbofloxacin

    Fluoroquinolone; bacterial DNA gyrase inhibitor...

    ≥98%
  • A5228

    Angiogenin

    Small protein, cleaves RNA.

    ≥98%
  • T0249

    Tamibarotene

    RARα/β agonist.

    ≥98%
  • T0154

    Tanshinone IIA

    Found in Salvia; MAG lipase inhibitor.

    ≥93%
  • P4782

    PluriSIn 1

    Stearoyl-coA desaturase 1 inhibitor.

    ≥98%
  • A5070

    Angiotensin Acetate

    Peptide, derivative of AT I, cleavage product o...

    ≥95%
  • K9600

    KY-02111

    Wnt signaling inhibitor.

    ≥98%
  • T2835

    6-Thioguanine

    Nucleotide (guanine) analog, prevents guanine s...

    ≥90%
  • S760004

    Stachybotrylactam

    Spirodihydrobenzofuranlactam

    ≥98%
  • P7000

    PR-619

    Deubiquitinating enzyme inhibitor.

    ≥98%
  • G124080

    GDC-0994

    ERK1/2 inhibitor.

    ≥98%
  • D3431

    3,4-Dihydroxyphenyl Ethanol

    Polyphenol found in olive oil, antioxidant.

    ≥95%
  • L0108

    Lacidipine

    Calcium channel blocker.

    ≥98%