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Flutamide

Flutamide

Product ID F4680
Cas No. 13311-84-7
Purity ≥98%
Product Unit SizeCostQuantityStock
1 g $61.10 In stock
5 g $204.30 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Flutamide is a non-steroidal inhibitor of the androgen receptor; it exhibits anticancer chemotherapeutic, anti-inflammatory, and anti-androgenic activities. Flutamide is clinically used to treat prostate cancer and polycystic ovary syndrome. In prostate cancer cells, flutamide induces S phase cell cycle arrest and inhibits cellular proliferation. Flutamide also decreases activation of NF-κB, release of pro-inflammatory cytokines, and activity of myeloperoxidase in animal models of hepatic trauma.

Product Info

Cas No.

13311-84-7

Purity

≥98%

Formula

C11H11F3N2O3

Formula Wt.

276.22

Chemical Name

2-Methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]- propanamide

IUPAC Name

2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide

Synonym

Drogenil, Euflex, Flucinom, Fugerel

Melting Point

111.5-112.5°C

Solubility

Insoluble in water. Soluble in DMSO.

Appearance

A yellow crystalline powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

F4680 MSDS PDF

Info Sheet

F4680 Info Sheet PDF

References

Al-Saeedi F. Effects of flutamide on [methyl-(3)h]-choline uptake in human prostate cancer-3 cells: a pilot study. Curr Ther Res Clin Exp. 2007 Jul;68(4):226-41. PMID: 24683213.

Shimizu T, Yu HP, Hsieh YC, et al. Flutamide attenuates pro-inflammatory cytokine production and hepatic injury following trauma-hemorrhage via estrogen receptor-related pathway. Ann Surg. 2007 Feb;245(2):297-304. PMID: 17245185.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

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