Description
Flutriafol is a triazole antifungal pesticide; it acts as a demethylation inhibitor, preventing sterol biosynthesis and disrupting membrane function. Flutriafol may also exhibit neuromodulatory and antioxidative activity in vivo, as it induces release of dopamine in the rat striatum through overstimulation of NMDA receptors and increasing NO production. Flutriafol-evoked dopamine release also appears to be dependent on Na+ and Ca2+ signaling.