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Gabapentin

Gabapentin

Product ID G0106
Cas No. 60142-96-3
Purity ≥98%
Product Unit SizeCostQuantityStock
10 mg $66.20 In stock
50 mg $193.00 In stock
250 mg $385.90 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Gabapentin exhibits antiepileptic/anticonvulsant, sedative, analgesic, and antinociceptive activities. Gabapentin is a GABA analog that does not bind GABA receptors. Gabapentin binds the α2δ subunit of voltage-gated Ca2+ channels, decreasing Ca2+ currents and inhibiting Ca2+ signaling; gabapentin also activates adenosine A1 receptors, binds NMDA receptors, and potentiates the effects of GABA signaling. Gabapentin is clinically used to prevent seizures and to treat neuropathic, inflammatory, and cancer-related pain.

Product Info

Cas No.

60142-96-3

Purity

≥98%

Formula

C9H17NO2

Formula Wt.

171.24

Chemical Name

1-(Aminomethyl)-cyclohexaneacetic acid

IUPAC Name

2-[1-(aminomethyl)cyclohexyl]acetic acid

Synonym

GOE-3450, Neurontin

Melting Point

162-166°C

Solubility

Soluble in water (pH 7.4).

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

G0106 MSDS PDF

Info Sheet

G0106 Info Sheet PDF

References

Kukkar A, Bali A, Singh N, et al. Implications and mechanism of action of gabapentin in neuropathic pain. Arch Pharm Res. 2013 Mar;36(3):237-51. PMID: 23435945.

Davies A, Hendrich J, Van Minh AT, et al. Functional biology of the alpha(2)delta subunits of voltage-gated calcium channels. Trends Pharmacol Sci. 2007 May;28(5):220-8. PMID: 17403543.

Johannessen SI, Ben-Menachem E. Management of focal-onset seizures: an update on drug treatment. Drugs. 2006;66(13):1701-25. PMID: 16978035.

Ho KY, Gan TJ, Habib AS. Gabapentin and postoperative pain--a systematic review of randomized controlled trials. Pain. 2006 Dec 15;126(1-3):91-101. PMID: 16846695.

Custom Order

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