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Granisetron Hydrochloride

Granisetron Hydrochloride

Product ID G6802
Cas No. 107007-99-8
Purity ≥98%
Product Unit SizeCostQuantityStock
25 mg $98.60 In stock
100 mg $281.60 In stock
500 mg $1,127.10 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Granisetron is an antagonist at 5-HT3 receptors that exhibits antiemetic and anti-inflammatory activities. Unlike most similar-acting antiemetics, granisetron does not effect the cytochrome p450 metabolizing system. In animal models of colitis, this compound inhibited post-inflammatory visceral sensitivity.

Product Info

Cas No.

107007-99-8

Purity

≥98%

Formula

C18H24N4O • HCl

Formula Wt.

348.87

Chemical Name

Endo-1-methyl-N-(9-methyl-9-aza bicyclo [3.3.1]non-3-yl)-1H-Indazole-3-carboxamide hydrochloride

IUPAC Name

1-methyl-N-(9-methyl-9-azabicyclo[3.3.1]nonan-3-yl)indazole-3- carboxamide;hydrochloride

Solubility

Soluble in water, DMSO, methanol, and ethanol.

Appearance

White or pale Yellow crystalline Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

G6802 MSDS PDF

Info Sheet

G6802 Info Sheet PDF

References

Hsu ES. A review of granisetron, 5-hydroxytryptamine3 receptor antagonists, and other antiemetics. Am J Ther. 2010 Sep-Oct;17(5):476-86. PMID: 20844345.

Choi YD, Sung TS, Kim HJ, et al. Increased 5-hydroxytryptamine mediates post-inflammatory visceral hypersensitivity via the 5-hydroxytryptamine 3 receptor in rats. Dig Dis Sci. 2008 Nov;53(11):2909-16. PMID: 18357529.

Martin C, Roman V, Agay D, et al. Anti-emetic effect of ondansetron and granisetron after exposure to mixed neutron and gamma irradiation. Radiat Res. 1998 Jun;149(6):631-6. PMID: 9611102.

Custom Order

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