Description
GS-9901 is a selective inhibitor of the delta isoform of PI3K (PI3Kδ). PI3Kδ is overexpressed in many hematological malignancies as well as rheumatoid arthritis.
| Product Unit Size | Cost | Quantity | Stock |
|---|
GS-9901 is a selective inhibitor of the delta isoform of PI3K (PI3Kδ). PI3Kδ is overexpressed in many hematological malignancies as well as rheumatoid arthritis.
| Cas No. | 1640247-87-5 |
|---|---|
| Purity | ≥99% |
| Formula | C22H17ClFN9O |
| Formula Wt. | 477.89 |
| IUPAC Name | 2,4-Diamino-6-({[5-chloro-8-fluoro-4-oxo-3-(3-pyridinyl)-3,4-dihydro-2-quinazolinyl](cyclopropyl)methyl}amino)-5-pyrimidinecarbonitrile |
| Synonym | GS 9901, GS9901 |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Patel L., Chandrasekhar J., et al. Discovery of Orally Efficacious Phosphoinositide 3-Kinase δ Inhibitors with Improved Metabolic Stability. J Med Chem. 59(19):9928-42 (2016). PMID:27660855.
Antioxidant, vitamin E derivative found in vege...
MEK inhibitor.
PERK inhibitor.
Organosulfur found in garlic; Microtubule polym...
β-lactam; penicillin binding protein inhibitor...
β-lactam; penicillin binding protein inhibitor...
G-quadruplex ligand; DNA breakage inducer.
Anthracycline, DNA intercalator; topoisomerase ...
Lincosamide; peptidyl transferase inhibitor, pr...
Endogenous peptide hormone fragment, involved i...
Endogenous peptide hormone, GLP-1 fragment, inv...
Trihydroxybenzoic acid glycoside found in Berge...
MGMT inhibitor.
Endogenous sphingolipid involved in cell signal...
AhR agonist.
Active form of vitamin D, regulates dietary Ca2...
Synthetic peptice; μOR agonist.
RT inhibitor.
ITC, erucin analog.
Aminoglycoside; protein translation inhibitor, ...