Description
GS-9901 is a selective inhibitor of the delta isoform of PI3K (PI3Kδ). PI3Kδ is overexpressed in many hematological malignancies as well as rheumatoid arthritis.
| Product Unit Size | Cost | Quantity | Stock |
|---|
GS-9901 is a selective inhibitor of the delta isoform of PI3K (PI3Kδ). PI3Kδ is overexpressed in many hematological malignancies as well as rheumatoid arthritis.
| Cas No. | 1640247-87-5 |
|---|---|
| Purity | ≥99% |
| Formula | C22H17ClFN9O |
| Formula Wt. | 477.89 |
| IUPAC Name | 2,4-Diamino-6-({[5-chloro-8-fluoro-4-oxo-3-(3-pyridinyl)-3,4-dihydro-2-quinazolinyl](cyclopropyl)methyl}amino)-5-pyrimidinecarbonitrile |
| Synonym | GS 9901, GS9901 |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Patel L., Chandrasekhar J., et al. Discovery of Orally Efficacious Phosphoinositide 3-Kinase δ Inhibitors with Improved Metabolic Stability. J Med Chem. 59(19):9928-42 (2016). PMID:27660855.
Mycotoxin derivative; actin polymerization inhi...
TRPM8 activator, TRPV3 blocker.
AT1 inhibitor.
Tenoxicam impurity
STING antagonist
Benzimidazole; microtubule polymerization inhib...
Polyene macrolide; ergosterol inhibitor.
Pt-based DNA cross-linker.
Cholesterol ester transfer protein inhibitor.
Natriuretic, vasodilatory peptide fragment; B1/...
PKA substrate.
Impurity of omeprazole
α7 and β4 nAChR agonist, α4β2 and α6β2 nA...
Peptide found in insects.
mTOR inhibitor.
Mycotoxin produced by Aspergillus; actin polyme...
Macrolide; protein synthesis inhibitor.
Tetrapeptide, binds cell surface integrins.
Peptide hormone found in Solanaceae family plan...
Viral RNA polymerase inhibitor.