Description
GS-9901 is a selective inhibitor of the delta isoform of PI3K (PI3Kδ). PI3Kδ is overexpressed in many hematological malignancies as well as rheumatoid arthritis.
| Product Unit Size | Cost | Quantity | Stock |
|---|
GS-9901 is a selective inhibitor of the delta isoform of PI3K (PI3Kδ). PI3Kδ is overexpressed in many hematological malignancies as well as rheumatoid arthritis.
| Cas No. | 1640247-87-5 |
|---|---|
| Purity | ≥99% |
| Formula | C22H17ClFN9O |
| Formula Wt. | 477.89 |
| IUPAC Name | 2,4-Diamino-6-({[5-chloro-8-fluoro-4-oxo-3-(3-pyridinyl)-3,4-dihydro-2-quinazolinyl](cyclopropyl)methyl}amino)-5-pyrimidinecarbonitrile |
| Synonym | GS 9901, GS9901 |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Patel L., Chandrasekhar J., et al. Discovery of Orally Efficacious Phosphoinositide 3-Kinase δ Inhibitors with Improved Metabolic Stability. J Med Chem. 59(19):9928-42 (2016). PMID:27660855.
Endogenous cardiomodulatory peptide; NPR-A agon...
Toxin produced by Canarthis vesicatoria; PP1/2A...
Polypeptide; peptidoglycan inhibitor.
Neuropeptide hormone found in arthropods.
Mycotoxin produced by Penicillum and Aspergillu...
Antioxidant, vitamin E derivative found in vege...
Water-soluble cortisol derivative; glucocortico...
Endogenous peptide, involved in water/Na+ homeo...
Synthetic type II pyrethroid insecticide; prote...
Indoline; D2/3 agonist.
Cyclic depsipeptide is a secondary metabolite i...
TGR5 agonist.
Isothiocyanate found in cruciferous vegetables,...
Polymethoxylated flavone found in citrus fruits...
Paclitaxel derivative
Endogenous peptide hormone, involved in growth ...
FAAH inhibitor.
Casein kinase 1 inhibitor.
Pyrimidine analog, fluorouracil derivative; thy...
Centrally acting muscle relaxant.