Description
GS-9901 is a selective inhibitor of the delta isoform of PI3K (PI3Kδ). PI3Kδ is overexpressed in many hematological malignancies as well as rheumatoid arthritis.
| Product Unit Size | Cost | Quantity | Stock |
|---|
GS-9901 is a selective inhibitor of the delta isoform of PI3K (PI3Kδ). PI3Kδ is overexpressed in many hematological malignancies as well as rheumatoid arthritis.
| Cas No. | 1640247-87-5 |
|---|---|
| Purity | ≥99% |
| Formula | C22H17ClFN9O |
| Formula Wt. | 477.89 |
| IUPAC Name | 2,4-Diamino-6-({[5-chloro-8-fluoro-4-oxo-3-(3-pyridinyl)-3,4-dihydro-2-quinazolinyl](cyclopropyl)methyl}amino)-5-pyrimidinecarbonitrile |
| Synonym | GS 9901, GS9901 |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Patel L., Chandrasekhar J., et al. Discovery of Orally Efficacious Phosphoinositide 3-Kinase δ Inhibitors with Improved Metabolic Stability. J Med Chem. 59(19):9928-42 (2016). PMID:27660855.
β-lactam; penicillin binding protein inhibitor...
SIRT inhibitor.
Dipeptide ester, commercial sweetener.
Neuroactive mycotoxin produced by Penicillum an...
Iridoid glycoside found in Gardinia jasminoides...
Optically active isomer of ibuprofen, NSAID; CO...
Selective inhibitor of cytochrome P450 1B1 (CYP...
Cyclic peptide; calcineurin inhibitor.
Mycotoxin contaminant found in cereal grains.
Echinocandin antifungal
Triazole; gibberellin inhibitor, potential 14-Î...
Synthetic peptide, fibrinogen derivative; glyco...
SGLT2 inhibitor
Triterpene saponin found in Panax.
Dienolide kavalactone originally found in Piper...
ATR inhibitor.
Endogenous peptide, involved in paracrine and a...
Peptide used to measure in vitro calcineurin ac...
Mycotoxin produced by various fungi including t...
Derivative of methyl caffeate, hydroxycinnamic ...