Description
GS-9901 is a selective inhibitor of the delta isoform of PI3K (PI3Kδ). PI3Kδ is overexpressed in many hematological malignancies as well as rheumatoid arthritis.
| Product Unit Size | Cost | Quantity | Stock |
|---|
GS-9901 is a selective inhibitor of the delta isoform of PI3K (PI3Kδ). PI3Kδ is overexpressed in many hematological malignancies as well as rheumatoid arthritis.
| Cas No. | 1640247-87-5 |
|---|---|
| Purity | ≥99% |
| Formula | C22H17ClFN9O |
| Formula Wt. | 477.89 |
| IUPAC Name | 2,4-Diamino-6-({[5-chloro-8-fluoro-4-oxo-3-(3-pyridinyl)-3,4-dihydro-2-quinazolinyl](cyclopropyl)methyl}amino)-5-pyrimidinecarbonitrile |
| Synonym | GS 9901, GS9901 |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Patel L., Chandrasekhar J., et al. Discovery of Orally Efficacious Phosphoinositide 3-Kinase δ Inhibitors with Improved Metabolic Stability. J Med Chem. 59(19):9928-42 (2016). PMID:27660855.
Sulforaphane-cysteine conjugate.
SV2A synaptic vesicle inhibitor.
Nucleoside (cytidine) analog; RT and telomerase...
Found in Aconitum bulleyanum; voltage-gated Na+...
Triazole; 14-α demethylase inhibitor, voltage-...
Tenoxicam impurity
Fluoroquinolone; bacterial DNA gyrase inhibitor...
Selective inhibitor of cytochrome P450 1B1 (CYP...
Cathepsin K inhibitor.
5-Fluorouracil prodrug, pyrimidine nucleoside a...
Diterpene found in coffee beans.
Piperadine phenothiazine; FIASMA, D1-5, histami...
Sesquiterpene lactone derived from Artemesia; m...
Cysteine-ITC conjugate, antioxidant.
Endogenous peptide hormone fragment, involved i...
Synthetic kahweol derivative.
Peptide, used as control to measure RGDS peptid...
CRM1/XPO1 inhibitor.
Fermentation impurity
Endogenous opioid peptide derived from the β-c...