Description
Ibotenic acid is an excitotoxin which causes neuroinflammation. It causes neuron injury and cell death by inducing excessive calcium influx.
Ibotenic Acid
Product ID I058584
Cas No. 2552-55-8
Purity ≥98%
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Product Info
| Cas No. | 2552-55-8 |
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| Purity | ≥98% |
| Formula | C5H6N2O4 |
| Formula Wt. | 158.11 |
| Chemical Name | DL-Ibotenic acid; |
| IUPAC Name | 2-amino-2-(3-oxo-1,2-oxazol-5-yl)acetic acid |
| Synonym | Ibotenate; (+/-)-Ibotenic acid; DL-Ibotenic acid; (RS)-Ibotenic acid; alpha-Amino-2,3-dihydro-3-oxo-5-isoxazoleacetic acid; alpha-Amino-3-hydroxy-5-isoxazoleacetic acid |
Shipping and Storage
| Store Temp | -20°C |
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| Ship Temp | Ambient |
Downloads
| Info Sheet |
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References
Ittiyavirah S, Ramalingam K, Sathyan A, et al. Thymoquinone-rich blank cumin oil attenuates ibotenic acid-induced excitotoxicity through glutamate receptors in Wistar rats. Saudi Pharm J. 2022 Dec;30(12):1781-1790. PMID: 36601514.
Yao L, Wang J, Liu C, et al. Cordydepin protects against beta-amyloid and ibotenic acid-induced hippocampal CA1 pyramidal neuronal hyperactivity. Korean J Physiol Pharmacol. 2019 Nov;23(6):483-491. PMID: 31680770.
Karthick C, Periyasamy S, Jayachandran K, et al. Intrahippocampal administration of ibotenic acid induced cholinergic dysfunction via NR2A/NR2B expression: implications of resveratrol against Alzheimer disease pathophysiology. Front Mol Neurosci. 2016 Apr 26:9:28. PMID: 27199654.