Description
INH1 is a small molecule found to disrupt the Hec1/Nek2 interaction via direct Hec1 binding, leading to apoptosis.
INH1 is a small molecule found to disrupt the Hec1/Nek2 interaction via direct Hec1 binding, leading to apoptosis.
| Cas No. | 313553-47-8 |
|---|---|
| Purity | ≥98% |
| Formula | C18H16N2OS |
| Formula Wt. | 308.40 |
| Chemical Name | N-(4-(2,4-Dimethylphenyl)thiazol-2-yl)benzamide |
| IUPAC Name | N-[4-(2,4-dimethylphenyl)-1,3-thiazol-2-yl]benzamide |
| Synonym | Hec1/Nek2 Mitotic Pathway Inhibitor I; Benzamide,N-[4-(2,4-dimethylphenyl)-2-thiazolyl]-; IBT13131; AC1LIOIV |
| Store Temp | 4°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Guikai Wu, Xiao-Long Qiu, Longen Zhou, et al. Small molecule targeting the Hec1/Nek2 mitotic pathway suppresses tumor cell growth in culture and in animal. Cancer Res. 2008, 68(20): 8393–8399. PMID 18922912.
Synthesis intermediate
Triterpenoid
Pt-based DNA cross-linker.
ROCK inhibitor.
5-HT2/3/6/7, D2/3/4, histamine H1, α1-adrenerg...
Cholesterol ester transfer protein inhibitor.
Non-endogenous essential amino acid found in me...
STING agonist
Mycotoxin produced by Fusarium; sphingosine acy...
Fluoroquinolone; topoisomerase IV and bacterial...
Pesticide; demethylation inhibitor.
Triterpene saponin found in Panax; Kv7.1 K+ cha...
Endogenous peptide hormone, involved in enteric...
Peptide, urocortin III analog; CRFR2 agonist.
Bosutinib isomer; Src and Abl inhibitor.
Nucleoside (cytidine) analog; DNMT inhibitor, p...
Mycotoxin produced by Fusarium fungi that infec...
Ornithine decarboxylase inhibitor.
Phytoestrogen found in various plant sources; E...
Endogenous calcitonin-family peptide, involved ...