Description
INH1 is a small molecule found to disrupt the Hec1/Nek2 interaction via direct Hec1 binding, leading to apoptosis.
INH1 is a small molecule found to disrupt the Hec1/Nek2 interaction via direct Hec1 binding, leading to apoptosis.
Cas No. | 313553-47-8 |
---|---|
Purity | ≥98% |
Formula | C18H16N2OS |
Formula Wt. | 308.40 |
Chemical Name | N-(4-(2,4-Dimethylphenyl)thiazol-2-yl)benzamide |
IUPAC Name | N-[4-(2,4-dimethylphenyl)-1,3-thiazol-2-yl]benzamide |
Synonym | Hec1/Nek2 Mitotic Pathway Inhibitor I; Benzamide,N-[4-(2,4-dimethylphenyl)-2-thiazolyl]-; IBT13131; AC1LIOIV |
Store Temp | 4°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Guikai Wu, Xiao-Long Qiu, Longen Zhou, et al. Small molecule targeting the Hec1/Nek2 mitotic pathway suppresses tumor cell growth in culture and in animal. Cancer Res. 2008, 68(20): 8393–8399. PMID 18922912.
FIASMA, L-type Ca2+ channel blocker, D2 antagon...
Synthetic antioxidant that induces phase II enz...
FLT3, PDGFR inhibitor.
Glycosaminoglycan
Ellagic acid derivative produced by gut microfl...
Purine nucleotide analog, mercaptiopurine prodr...
Saponin found in Polygala.
Purine nucleoside analog; DNA chain terminator....
Nucleoside (deoxyguanosine) analog; DNA chain t...
Peptide, derivative of AT II, involved in vasoc...
Thiamine, coccidiostat; thiamine transporter in...
Diterpene found in brewed, unfiltered coffee; F...
Thienylbutyl ITC analog.
Glycopeptide, binds D-Ala-D-Ala; cell wall synt...
Cembranoid diterpene found in Sarcophyton glauc...
Dibenzocyclooctadiene found in Schisandra.
Nucleoside (deoxyuridine) analog; DNA chain ter...
Indoleamine 2,3-dioxygenase inhibitor.
Triterpene; potential tyrosinase inhibitor.