LKT Labs

Biochemicals for Life Science Research

Enalaprilat Dihydrate

Enalaprilat Dihydrate

Product ID E5200
Cas No. 84680-54-6
Purity ≥98%
Product Unit SizeCostQuantityStock
10 mg $172.10 In stock
50 mg $744.90 In stock
100 mg $1,374.30 In stock
Bulk Quote

Quicklinks

Description

Enalaprilat is the active metabolite of enalapril. Enalapril is an angiotensin-converting enzyme (ACE) inhibitor that is clinically used to treat hypertension, heart failure, and diabetic nephropathy. Enalapril exhibits antihypertensive activity. Enalapril prevents and reverses renovascular hypertension-induced smooth muscle hypertrophy, collagen deposition, carotid media thickness growth, and other parameters of arterial remodeling. Additionally, enalapril improves endothelial function in migraine sufferers by increasing levels of NO.

Product Info

Cas No.

84680-54-6
Purity

≥98%
Formula

C18H24N2O5 • 2H2O
Formula Wt.

384.42
Chemical Name

N-[(1S)-Carboxy- 3-phenylpropyl]-L-alanyl-L-proline dihydrate

IUPAC Name

(2S)-1-[(2S)-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]propanoyl]pyrrolidine-2-carboxylic acid;dihydrate

Synonym

Enalaprilic acid, Vasotec IV
Melting Point

148-151°C
Solubility

Slightly soluble in water (14 mg/mL at 60 oC) DMSO (64 mg/mL), methanol (14 mg/mL).

Appearance

White or almost white crystalline powder

Shipping and Storage

Store Temp

Ambient
Ship Temp

Ambient

Downloads

MSDS

E5200 MSDS PDF
Info Sheet

E5200 Info Sheet PDF

References

Chen JL, Shang QH, Hu W, et al. Role of TGF-β1/Smads pathway in carotid artery remodeling in renovascular hypertensive rats and prevention by Enalapril and Amlodipine. J Geriatr Cardiol. 2012 Jun;9(2):185-91. PMID: 22916067.

Bilan VP, Salah EM, Bastacky S, et al. Diabetic nephropathy and long-term treatment effects of rosiglitazone and enalapril in obese ZSF1 rats. J Endocrinol. 2011 Sep;210(3):293-308. PMID: 21680617.

Javanmard SH, Sonbolestan SA, Heshmat-Ghahdarijani K, et al. Enalapril improves endothelial function in patients with migraine: A randomized, double-blind, placebo-controlled trial. J Res Med Sci. 2011 Jan;16(1):26-32. PMID: 21448379.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • T3584

    Tivantinib

    MET and GSK-3α/β inhibitor.

    ≥98%
  • M1687

    Mevinolin

    Statin, naturally produced by mushrooms; HMG-Co...

    ≥97%
  • A7462

    Aspartame

    Dipeptide ester, commercial sweetener.

    ≥98%
  • G7200

    GS-967

    Na+ channel blocker.

    ≥98%
  • M002698

    M2698

    Dual inhibitor of p70S6K and Akt.

    ≥99%
  • C9710

    Cyclopamine

    Steroidal jerveratrum alkaloid found in Veratru...

    ≥98%
  • T1008

    10,13-Bissidechain Paclitaxel

    Synthesis impurity

    ≥90%
  • P0344

    Palbociclib Isethionate

    CDK4/6 inhibitor.

    ≥98%
  • M9368

    Myristicin

    Allylbenzene found in spices and umbelliferous ...

    ≥98%
  • B1603

    Beauvericin

    Cyclic hexadepsipeptide mycotoxin produced by C...

    ≥95%
  • S520011

    SN-011

    STING antagonist

    ≥97%
  • V0245

    Valdecoxib

    NSAID; CB1 agonist, COX-2 inhibitor.

    ≥98%
  • D1644

    Deltorphin I

    Opioid peptide; δOR agonist.

    ≥98%
  • A7604

    ATB 346

    NSAID; COX inhibitor and HS-releasing agent.

    ≥99%
  • G1210

    GDC-0623

    MEK inhibitor.

    ≥98%
  • G0104

    Gabexate Mesylate

    Proteasome inhibitor.

    ≥99%
  • L3453

    Linezolid

    Oxazolidinone; protein synthesis inhibitor.

    ≥99%
  • T1878

    Tetrodotoxin Citrate

    Neurotoxin found in puffer fish; site 1 voltage...

    ≥99%
  • G4518

    Glucaric Acid Calcium Tetrahydrate

    Oxidized non-cylic hexose sugar.

    ≥98%
  • R5772

    Rosiglitazone Maleate

    Thiazolidinedione; PPARγ agonist.

    ≥98%