• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Irsogladine Maleate

Irsogladine Maleate

Product ID I7074
Cas No. 84504-69-8
Purity ≥98%
Product Unit SizeCostQuantityStock
100 mg $139.00 In stock
500 mg $433.90 In stock
1 g $694.40 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Irsogladine exhibits anti-inflammatory, anti-fibrotic, and mucoprotective activities. Irsogladine decreases non-steroidal anti-inflammatory drug (NSAID)-induced intestinal mucosal injury, ulcers, and esophagitis; it inhibits COX-1 and COX-2. In animal models of colitis, irsogladine prevents DDS-induced increases in TGF-β1, collagen type 1, MMP2, TIMP-1, and α-SMA, preventing fibrosis. Additionally, irsogladine non-selectively inhibits phosphodiesterases, increasing cAMP and NO, facilitating gap junction communication and altering gastric mucosal blood flow.

Product Info

Cas No.

84504-69-8

Purity

≥98%

Formula

C9H7Cl2N5 • C4H4O4

Formula Wt.

372.17

Chemical Name

6-(2,5-Dichlorophenyl)-1,3,5-triazine-2,4-diamine maleate

IUPAC Name

(Z)-but-2-enedioic acid;6-(2,5-dichlorophenyl)-1,3,5-triazine-2,4-diamine

Synonym

MN-1695, Gaslon

Melting Point

289-294°C

Solubility

Soluble in DMSO.

Appearance

White Crystalline Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

I7074 MSDS PDF

Info Sheet

I7074 Info Sheet PDF

References

Kuramoto T, Umegaki E, Nouda S, et al. Preventive effect of irsogladine or omeprazole on non-steroidal anti-inflammatory drug-induced esophagitis, peptic ulcers, and small intestinal lesions in humans, a prospective randomized controlled study. BMC Gastroenterol. 2013 May 14;13:85. PMID: 23672202.

Akagi M, Amagase K, Murakami T, et al. Irsogladine: overview of the mechanisms of mucosal protective and healing- promoting actions in the gastrointestinal tract. Curr Pharm Des. 2013;19(1):106-14. PMID: 22950502.

Yamaguchi H, Suzuki K, Nagata M, et al. Irsogladine maleate ameliorates inflammation and fibrosis in mice with chronic colitis induced by dextran sulfate sodium. Med Mol Morphol. 2012 Jun;45(3):140-51. PMID: 23001296.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • F4501

    Flavanone

    Variety of flavonoid found in various plant sou...

    ≥98%
  • G4781

    Glucoraphanin Potassium

    Glucosinolate found in cruciferous vegetables.<...

    ≥98%
  • F7657

    Ftorafur

    5-fluorouracil prodrug, pyrimidine analog; thym...

    ≥99%
  • A081014

    Acalabrutinib

    Inhibitor of Bruton’s tyrosine kinase (BTK).<...

    ≥99%
  • A9601

    AZD-5363

    AKT inhibitor, potential ROCK, p70S6K, PKA, MKK...

    ≥99%, ≥99%ee
  • T7133

    Trimetazidine Dihydrochloride

    Long-chain 3-ketoacyl-CoA thiolase inhibitor, p...

    ≥99%
  • D564090

    7-epi-Docetaxel

    Docetaxel impurity

    ≥95%
  • F4557

    Floxuridine

    5-Fluorouracil derivative, fluorinated pyrimidi...

    ≥98%
  • H9618

    Hydroquinone

    Basic phenol skeleton structure found in variou...

    ≥96%
  • B5074

    BMS-599626

    EGFR, VEGFR inhibitor.

    ≥98%
  • U682042

    URB602

    Inhibitor of Monoacyglycerol lipase (MAGL).

    ≥98%
  • M3584

    Mivacurium

    Non-depolarizing NMJ blocker; nAChR antagonist....

    ≥98%
  • I5357

    Inositol

    Endogenous sugar produced from glucose, require...

    ≥98%
  • D0032

    Daidzein

    Phytoestrogen, isoflavone found in various plan...

    ≥97%
  • A4931

    3-Aminobenzamide

    PARP inhibitor.

    ≥97%
  • P0013

    P7C3

    Aminopropyl carbazole, neuroprotective.

    ≥98%
  • W0272

    S-(−)-Warfarin >99%ee

    Coumarin, more potent isomer; VKORC1 inhibitor....

    ≥99%
  • C0145

    Calcitriol

    Active form of vitamin D, regulates dietary Ca2...

    ≥97%
  • C1649

    β-Cembrenediol

    Diterpene found in Anisomeles.

    ≥99%
  • A7672

    Atropine Sulfate Monohydrate

    Tropane alkaloid found in Solanaceae plants; mA...

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only