| Product Unit Size | Cost | Quantity | Stock |
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Kb NB 77-78 is an inactive analog of CID-797718 and showing no binding to PKD1. CID-797718 is a synthetic byproduct in the synthesis of CID-755673. Although CID-797718 showed moderate activity, the analog of Kb NB 77-78 showed decreased, rather than increased activity.
| Cas No. | 1350622-33-1 |
|---|---|
| Purity | ≥98% |
| Formula | C18H25NO3Si |
| Formula Wt. | 331.49 |
| IUPAC Name | 9-{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}-1,2,3,4-tetrahydro-5H-chromeno[3,4-b]pyridin-5-one |
| Synonym | CID-797718 Analog, Kb-NB77-78, KbNB7778 |
| Solubility | 100 mM in DMSO |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
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| Info Sheet |
George K, Frantz M, Bravo-Altamirano K, et al. Design, synthesis, and biological evaluation of PKD inhibitors. Pharmaceutics. 2011;3(2):186-228. PMID: 22267986.