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Kobe 0065

Kobe 0065

Product ID K5604
Cas No. 436133-68-5
Purity ≥99%
Product Unit SizeCostQuantityStock
5 mg $126.50 In stock
25 mg $498.10 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Kobe 0065 is an inhibitor of Ras that exhibits anticancer chemotherapeutic activities. In vitro, this compound inhibits cell growth and induces apoptosis and in vivo, it decreases tumor growth.

Product Info

Cas No.

436133-68-5

Purity

≥99%

Formula

C15H11ClF3N5O4S

Formula Wt.

449.79

IUPAC Name

N-(3-Chloro-4-methylphenyl)-2-[2,6-dinitro-4-(trifluoromethyl)phenyl]hydrazinecarbothioamide

Solubility

ethanol 10mM with gentle warming water 5 mM with gentle warming

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

K5604 MSDS PDF

Info Sheet

K5604 Info Sheet PDF

References

Shima F, Yoshikawa Y, Ye M, et al. In silico discovery of small-molecule Ras inhibitors that display antitumor activity by blocking the Ras-effector interaction. Proc Natl Acad Sci U S A. 2013 May 14;110(20):8182-7. PMID: 23630290.

Shima F, Yoshikawa Y, Matsumoto S, et al. Discovery of small-molecule Ras inhibitors that display antitumor activity by interfering with Ras·GTP-effector interaction. Enzymes. 2013;34 Pt. B:1-23. PMID: 25034098.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
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