• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Kobe 0065

Kobe 0065

Product ID K5604
Cas No. 436133-68-5
Purity ≥99%
Product Unit SizeCostQuantityStock
5 mg $126.50 In stock
25 mg $498.10 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Kobe 0065 is an inhibitor of Ras that exhibits anticancer chemotherapeutic activities. In vitro, this compound inhibits cell growth and induces apoptosis and in vivo, it decreases tumor growth.

Product Info

Cas No.

436133-68-5

Purity

≥99%

Formula

C15H11ClF3N5O4S

Formula Wt.

449.79

IUPAC Name

N-(3-Chloro-4-methylphenyl)-2-[2,6-dinitro-4-(trifluoromethyl)phenyl]hydrazinecarbothioamide

Solubility

ethanol 10mM with gentle warming water 5 mM with gentle warming

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

K5604 MSDS PDF

Info Sheet

K5604 Info Sheet PDF

References

Shima F, Yoshikawa Y, Ye M, et al. In silico discovery of small-molecule Ras inhibitors that display antitumor activity by blocking the Ras-effector interaction. Proc Natl Acad Sci U S A. 2013 May 14;110(20):8182-7. PMID: 23630290.

Shima F, Yoshikawa Y, Matsumoto S, et al. Discovery of small-molecule Ras inhibitors that display antitumor activity by interfering with Ras·GTP-effector interaction. Enzymes. 2013;34 Pt. B:1-23. PMID: 25034098.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • P7021

    Prednisone Acetate

    Synthetic prednisolone prodrug; glucocorticoid ...

    ≥98%
  • K0022

    K252b

    Staurosporine analog; PKC inhibitor.

    ≥98%
  • P3568

    Pirarubicin

    Anthracycline, DNA intercalator; topoisomerase ...

    ≥98%
  • S8110

    Sucralfate

    Antacid; pepsin inhibitor. Assay (Polysaccharid...

    Assay (Polysaccharide sulfate) 30-38%
  • R5878

    Rotenone

    Micronuclei formation inducer, antimitotic, oxi...

    ≥97%
  • K0276

    Katacalcin

    Peptide found in crustaceans; PKA activator. &n...
    ≥95%
  • C6982

    Crustacean Cardioactive Peptide

    Neuropeptide hormone found in arthropods.

    ≥95%
  • C0367

    S-(−)-Carbidopa Monohydrate

    Hydrazine; L-amino acid decarboxylase inhibitor...

    ≥98%
  • P0932

    PCI-32765

    BTK and IL-2-inducible kinase inhibitor.  
    ≥99%
  • A4400

    Alamethicin

    Antimicrobial peptide found in Trichoderma, induce...
    ≥95%
  • A686164

    Arecaidine Hydrochloride

    mAChR agonist, selective for M2.

    ≥98%
  • N7200

    NS-11394

    GABA-A α5/3/2 positive modulator.

    ≥98%
  • I7259

    Isoproterenol Hydrochloride

    β-adrenergic agonist.

    ≥98%
  • U0618

    Ubenimex

    Dipeptide; aminopeptidase (N/CD13) inhibitor.

    ≥98%
  • C0160

    Canrenone

    Metabolite of spironolactone; Na+/K+ ATPase par...

    ≥98%
  • T1679

    Tetracycline Hydrochloride

    Polyketide; protein translation inhibitor, mamm...

    ≥95%
  • O456505

    Olmutinib

    EGFR inhibitor.

    ≥98%
  • M568262

    Mogrol

    Triterpenoid

    ≥99%
  • G3359

    Ginkgolide J

    Terpene lactone found in Ginkgo.

    ≥98%
  • K624760

    KPT-276

    CRM1/XPO1 inhibitor.

    ≥99%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only