• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Leptin (22-56), human

Leptin (22-56), human

Product ID L1660
Cas No.
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $525.00 Please Inquire
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Leptin is an endogenous peptide that binds leptin receptors; it is involved in feeding behavior and energy homeostasis. Leptin exhibits anorexigenic, antihypertensive, and neuroprotective activities. Leptin induces secretion of α-melanocyte-stimulating hormone (α-MSH) and gonadotropin-releasing hormone (GnRH). In obese and hypertensive rats, leptin decreases blood pressure. This peptide also inhibits myocardial muscle contractility and modulates bone growth and resorption. Additionally, leptin may be involved in the development of atherosclerosis. In animal models of Alzheimer’s disease, leptin decreases levels of tau and amyloid-β (Aβ), improving cognitive performance.

Product Info

Purity

≥98%

Formula

C171H298N50O56

Formula Wt.

3950.56

Synonym

OBGRP(22-56), human

Solubility

Insoluble in water. Soluble in 60% acetonitrile containing 0.1% TFA.

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

Info Sheet

L1660 Info Sheet PDF

References

Comninos AN, Jayasena CN, Dhillo WS. The relationship between gut and adipose hormones, and reproduction. Hum Reprod Update. 2014 Mar-Apr;20(2):153-74. PMID: 24173881.

Greco SJ, Bryan KJ, Sarkar S, et al. Leptin reduces pathology and improves memory in a transgenic mouse model of Alzheimer's disease. J Alzheimers Dis. 2010;19(4):1155-67. PMID: 20308782.

Zhang W, Telemaque S, Augustyniak RA, et al. Adenovirus-mediated leptin expression normalises hypertension associated with diet-induced obesity. J Neuroendocrinol. 2010 Mar;22(3):175-80. PMID: 20059648.

Taleb S, Herbin O, Ait-Oufella H, et al. Defective leptin/leptin receptor signaling improves regulatory T cell immune response and protects mice from atherosclerosis. Arterioscler Thromb Vasc Biol. 2007 Dec;27(12):2691-8. PMID: 17690315.

Martin A, David V, Malaval L, et al. Opposite effects of leptin on bone metabolism: a dose-dependent balance related to energy intake and insulin-like growth factor-I pathway. Endocrinology. 2007 Jul;148(7):3419-25. PMID: 17431002.

Moynihan AT, Hehir MP, Glavey SV, et al. Inhibitory effect of leptin on human uterine contractility in vitro. Am J Obstet Gynecol. 2006 Aug;195(2):504-9. PMID: 16647683.

Mantzoros CS. The role of leptin in human obesity and disease: a review of current evidence. Ann Intern Med. 1999 Apr 20;130(8):671-80. PMID: 10215564.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • P0255

    Pantoprazole

    H+/K+ ATPase and ROCK-2 inhibitor.

    ≥98%
  • D4802

    17-Dimethylaminoethylamino Demethoxygeldanamycin

    Geldanamycin derivative; HSP90 inhibitor.

    ≥98%
  • K040007

    KB-0742

    CDK9 inhibitor.

    ≥98%
  • L8276

    Luteinizing Hormone Releasing Hormone

    Endogenous peptide hormone; GnRH agonist.

    ≥98%
  • C446176

    Clemastine Fumarate

    Antihistamine with potential neuroprotective ac...

    ≥99%
  • D3218

    Diethylstilbestrol

    Synthetic non-steroid endocrine disrupter; ER a...

    ≥98%
  • S0930

    Schisantherin A

    Dibenzocyclooctadiene found in Schisandra.

    ≥98%
  • D3302

    Diaveridine Hydrochloride

    Coccidiostat; dihydrofolate reductase inhibitor...

    ≥98%
  • T0216

    TAE-226

    FAK inhibitor.

    ≥98%
  • B1853

    1,4-Benzoquinone

    Precursor in the synthesis of hydroquinone, ant...

    ≥98%
  • L1786

    Levofloxacin Hydrochloride Monohydrate

    Fluoroquinolone, S-(-) isomer of ofloxacin; top...

    ≥90%
  • E9417

    Exendin-4

    Peptide, GLP-1 analog found in Heloderma; GLP-1...

    ≥95%
  • S336486

    Simeprevir

    NS3/4A inhibitor

    ≥99%
  • T0253

    Tangeretin

    Polymethoxy flavonoid found in citrus fruits.

    ≥98%
  • C2818

    Chelerythrine Chloride

    benzophenanthridine alkaloid found in Chelidoni...

    ≥98%
  • I5212

    Indirubin

    Bisindole isomer of indigo found in Indigo natu...

    ≥98%
  • H3277

    Histrelin Acetate

    Peptide, GnRH analog; GnRH agonist.
    ≥95%
  • T1006

    10-Acetoacetyl Paclitaxel

    Synthesis impurity

    ≥95%
  • L8010

    D-Luciferin Potassium

    Heterocyclic light-emitting compound, natural l...

    ≥98%
  • G3353

    Ginkgolic Acid (15:1)

    Found in Ginkgo; HIV protease and fatty acid sy...

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only