• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Moxifloxacin Hydrochloride

Moxifloxacin Hydrochloride

Product ID M5794
Cas No. 186826-86-8
Purity ≥98%
Product Unit SizeCostQuantityStock
25 mg $121.70 In stock
100 mg $217.20 In stock
500 mg $833.40 In stock
1 g $1,362.90 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Moxifloxacin is a fluoroquinolone antibiotic commonly used to treat ocular infections such as bacterial conjunctivitis as well as sinus and lung infections such as pneumonia. Moxifloxacin displays antibacterial efficacy against both gram negative and gram positive bacteria, preventing DNA synthesis in bacterial pathogens by inhibiting topoisomerase IV and bacterial DNA gyrase. This compound is currently being examined as a conjunctive therapy with anticancer agents against several forms of cancer due to its topoisomerase II inhibition. Combining moxifloxacin with anticancer agents yields a cytotoxic drug sparing effect due to the synergism of the mechanisms of action between moxifloxacin and the anticancer drugs.

Product Info

Cas No.

186826-86-8

Purity

≥98%

Formula

C21H24FN3O4 • HCl

Formula Wt.

437.89

Chemical Name

1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7- [(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]- 4-oxo-3-quinolinecarboxylic acid hydrochloride

IUPAC Name

7-[(4aS,7aS)-1,2,3,4,4a,5,7,7a-octahydropyrrolo[3, 4-b]pyridin-6-yl]-1-cyclopropyl-6-fluoro-8-methoxy-4-oxoquinoline-3- carboxylic acid;hydrochloride

Synonym

Actura, Avalox, Avelox, Octegra, Proflox

Melting Point

324-325°C

Solubility

Soluble in water (2.4 g/100 ml). Methanol, DMSO

Appearance

Almost white to yellowish crystalline powder

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

M5794 MSDS PDF

Info Sheet

M5794 Info Sheet PDF

References

Wohlkonig A, Chan PF, Fosberry AP, et al. Structural basis of quinolone inhibition of type IIA topoisomerases and target-mediated resistance. Nat Struct Mol Biol. 2010 Sep;17(9):1152-3. PMID: 20802486.

Reuveni D, Halperin D, Shalit I, et al. Moxifloxacin enhances etoposide-induced cytotoxic, apoptotic and anti-topoisomerase II effects in a human colon carcinoma cell line. Int J Oncol. 2010 Aug;37(2):463-71. PMID: 20596674.

Reuveni D, Halperin D, Fabian I, et al. Moxifloxacin increases anti-tumor and anti-angiogenic activity of irinotecan in human xenograft tumors. Biochem Pharmacol. 2010 Apr 15;79(8):1100-7. PMID: 20025849.

Laponogov I, Sohi MK, Veselkov DA, et al. Structural insight into the quinolone-DNA cleavage complex of type IIA topoisomerases. Nat Struct Mol Biol. 2009 Jun;16(6):667-9. PMID: 19448616.

Stroman DW, Dajcs JJ, Cupp GA, et al. In vitro and in vivo potency of moxifloxacin and moxifloxacin ophthalmic solution 0.5%, a new topical fluoroquinolone. Surv Ophthalmol. 2005 Nov;50 Suppl 1:S16-31. PMID: 16257308.

Aldred KJ, McPherson SA, Wang P, et al. Drug interactions with Bacillus anthracis topoisomerase IV: biochemical basis for quinolone action and resistance. Biochemistry. 2012 Jan 10;51(1):370-381. PMID: 22126453.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • A971336

    Azilsartan Medoxomil

    Prodrug

    ≥98%
  • D1869

    Deracoxib

    NSAID; COX-2 inhibitor.

    ≥99%
  • P2819

    6-Phenylhexa-3,5-dien-2-one

    Minor kavalactone originally found in Piper met...

    ≥96%
  • P4008

    PKC412

    Staurosporine derivative; PKC and FLT3 inhibito...

    ≥98%
  • L1869

    Lercanidipine Hydrochloride

    Calcium channel blocker.

    ≥98%
  • T0077

    Transactivator of Transcription Peptide (2-4)

    Peptide, contains two cell-penetrating sequence...

    ≥95%
  • P3465

    Piperine

    Alkaloid found in black and long peppers; TRPV1...

    ≥95%
  • R3013

    Recombinant TpN 44.50 protein

    Recombinant protein containing Treponema pallid...

    ≥95%
  • L5648

    Lomustine

    Nitrosourea, DNA alkylator.

    ≥98%
  • D8014

    DU-14

    Steroid sulfatase inhibitor.

    ≥98%
  • G124084

    GDC-0973

    MEK1 inhibitor.

    ≥99%
  • G5752

    Gonadorelin Acetate

    Synthetic peptide, GnRH derivative; GnRH agonist.
    ≥95%
  • R3014

    Recombinant TpN 47 protein

    Recombinant protein containing Treponema pallid...

    ≥95%
  • R1985

    Reveromycin A

    Isoleucyl-tRNA synthase inhibitor, osteoclast p...

    ≥98%
  • F4501

    Flavanone

    Variety of flavonoid found in various plant sou...

    ≥98%
  • N0263

    Naphazoline Nitrate

    α1-adrenergic agonist.

    ≥97%
  • C8070

    Curcumin, high purity

    Active compound found in turmeric; MST1 activat...

    ≥98%
  • C281006

    Chaetocin

    Chaetocin is naturally produced by Chaetomium s...

    ≥98%
  • O2146

    R-(+)-Ofloxacin

    Fluoroquinolone, optically active isomer of ofl...

    ≥98%
  • E537334

    Enniatin B

    Mycotoxin contaminant found in cereal grains.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only