Description
Myelin basic protein (68-82) is an immunodominant peptide epitope observed in multiple sclerosis; it may be used to induce immune tolerance and downregulate T cell reactivity to myelin.
| Product Unit Size | Cost | Quantity | Stock |
|---|
Myelin basic protein (68-82) is an immunodominant peptide epitope observed in multiple sclerosis; it may be used to induce immune tolerance and downregulate T cell reactivity to myelin.
| Cas No. | 98474-59-0 |
|---|---|
| Purity | ≥95% |
| Formula | C71H113N23O28 |
| Formula Wt. | 1736.8 |
| Synonym | MBP |
| Solubility | Soluble in water, DMSO. |
| Appearance | White to off white powder |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
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| Info Sheet |
Mantzourani ED, Platts JA, Brancale A, et al. Molecular dynamics at the receptor level of immunodominant myelin basic protein epitope 87-99 implicated in multiple sclerosis and its antagonists altered peptide ligands: triggering of immune response. J Mol Graph Model. 2007 Sep;26(2):471-81. PMID: 17392002.
Liu JQ, Bai XF, Shi FD, et al. Inhibition of experimental autoimmune encephalomyelitis in Lewis rats by nasal administration of encephalitogenic MBP peptides: synergistic effects of MBP 68-86 and 87-99. Int Immunol. 1998 Aug;10(8):1139-48. PMID: 9723700.
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