Neuropeptide FF

Name: Neuropeptide FF
SKU: N1984
Availability: InStock

Product ID N1984

Cas No. 99566-27-5

Purity ≥95%

Product Unit Size	Cost	Quantity		Stock

Bulk Quote

Quicklinks

Description
Product Info
Shipping and Storage
Downloads
References

Description

Neuropeptide FF is an endogenous RF amide family peptide that exhibits anti-inflammatory and anti-analgesic activities. Neuropeptide FF binds NPFF1/2 receptors in the brain, regulating blood pressure and hormone secretion. In LPS-stimulated macrophages, neuropeptide FF decreases NO production and inhibits NF-κB translocation; in animal models, it suppresses carrageenan-induced edema. Additionally, neuropeptide FF inhibits opioid-induced stress-mediated analgesia in the forced swim test, displaying anti-opioid activity.

Product Info

Cas No.	99566-27-5
Purity	≥95%
Formula	C₅₄H₇₆N₁₄O₁₀
Formula Wt.	1081.3
IUPAC Name	(2S)-2-[[(2S)-1-[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[(2-amino-3- phenylpropanoyl)amino]-4-methylpentanoyl]amino]-3-phenylpropanoyl]amino] -5-oxopentanoyl]pyrrolidine-2-carbonyl]amino]-N-[(2S)-1-[(1-amino-1-oxo- 3-phenylpropan-2-yl)amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl] pentanediamide
Synonym	NPFF, Octapeptide F8FA, F-8-F-NH2, Neuro FF Morphine Modulating Neuro F-8-F-NH2.
Solubility	Soluble in water (0.5 mg/mL).
Appearance	White to off white powder

Shipping and Storage

Store Temp	-20°C
Ship Temp	Ambient

Downloads

MSDS	N1984 MSDS PDF
Info Sheet	N1984 Info Sheet PDF

References

Sun YL, Zhang XY, Sun T, et al. The anti-inflammatory potential of neuropeptide FF in vitro and in vivo. Peptides. 2013 Sep;47:124-32. PMID: 23856454.

Jhamandas JH, Goncharuk V. Role of neuropeptide FF in central cardiovascular and neuroendocrine regulation. Front Endocrinol (Lausanne). 2013 Feb 7;4:8. PMID: 23404625.

Li N, Han ZL, Fang Q, et al. Neuropeptide FF and related peptides attenuates warm-, but not cold-water swim stress-induced analgesia in mice. Behav Brain Res. 2012 Aug 1;233(2):428-33. PMID: 22659392.

Custom Order

Name*
First Last
Company/Institution
Email*
Enter Email Confirm Email
Product ID
Product Name
Unit Size
Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
Unit Label
Quantity
Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
Comments
Comments
This field is for validation purposes and should be left unchanged.

Neuropeptide FF

Quicklinks

Description

Product Info

Shipping and Storage

Downloads

References

Custom Order

Related Products

Clofibric Acid

Paclitaxel, semi-synthetic

JWH 133

Phenethyl Isothiocyanate

Everolimus EP Impurity B

Nimorazole

Nutlin-3

Des(benzylpyridyl) Atazanavir

Iberverin

Bis(salicyl) Fumarate

Fluphenazine Hydrochloride

Terlipressin Acetate

Ac-DEVD-pNA

Bifonazole

Tiplaxtinin

2-(1,8-Naphthyridin-2-yl)phenol

Pipemidic Acid

Meso-2,3-dimercaptosuccinic Acid

Paeoniflorin

Fexofenadine Hydrochloride

Footer