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NLG919

NLG919

Product ID N4524
Cas No. 1402836-58-1
Purity ≥98%
Product Unit SizeCostQuantityStock
5 mg $144.00 In stock
25 mg $503.00 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

NLG919 is an inhibitor of indoleamine-2,3-dioxygenase (IDO). This compound displays anticancer chemotherapeutic activity, prolonging survival rates in animal models of glioblastoma.

Product Info

Cas No.

1402836-58-1

Purity

≥98%

Formula

C18H22N2O

Formula Wt.

282.39

Chemical Name

1-Cyclohexyl-2-(5H-imidazo[5,1-a]isoindol-5-yl)ethanol

IUPAC Name

1-Cyclohexyl-2-(5H-imidazo[5,1-a]isoindol-5-yl)ethanol

Synonym

NLG919 (GDC-0919), GTPL9019

Solubility

Ethanol 30 mg/mL (106.23 mM) DMSO 15 mg/mL warmed (53.11 mM) Water Insoluble

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

N4524 MSDS PDF

Info Sheet

N4524 Info Sheet PDF

References

Vacchelli E, Aranda F, Eggermont A, et al. Trial watch: IDO inhibitors in cancer therapy. Oncoimmunology. 2014 Dec 15;3(10):e957994. PMID: 25941578.

Li M, Bolduc AR, Hoda MN, et al. The indoleamine 2,3-dioxygenase pathway controls complement-dependent enhancement of chemo-radiation therapy against murine glioblastoma. J Immunother Cancer. 2014 Jul 7;2:21. PMID: 25054064.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
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