• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Norfloxacin

Norfloxacin

Product ID N5768
Cas No. 70458-96-7
Purity ≥98%
Product Unit SizeCostQuantityStock
1 g $37.10 In stock
5 g $83.40 In stock
10 g $143.40 In stock
50 g $510.30 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Norfloxacin is a first generation fluoroquinolone antibiotic that exhibits antibacterial, anti-inflammatory, and anticancer activities. Norfloxacin inhibits DNA gyrase and topoisomerase IV; it is clinically used to treat urinary tract infections and prostatitis. In neutrophils from cirrhotic subjects, norfloxacin increases expression of IL-10 and heme oxygenase 1 (HO-1) and decreases expression of pro-inflammatory cytokines. Additionally, when complexed with gold(III), norfloxacin binds DNA and inhibits cellular proliferation in several cancer cell lines.

Product Info

Cas No.

70458-96-7

Purity

≥98%

Formula

C16H18FN3O3

Formula Wt.

319.33

Chemical Name

1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid  

IUPAC Name

1-ethyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid

Synonym

Baccidal, Sebercim

Melting Point

227-228°C

Solubility

Soluble in water (0.28 mg/mL), methanol (1 mg/mL), ethanol (1.9 mg/mL).

Appearance

Yellowish white crystal powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

N5768 MSDS PDF

Info Sheet

N5768 Info Sheet PDF

References

Gouvea LR, Garcia LS, Lachter DR, et al. Atypical fluoroquinolone gold(III) chelates as potential anticancer agents: relevance of DNA and protein interactions for their mechanism of action. Eur J Med Chem. 2012 Sep;55:67-73. PMID: 22835721.

Gómez-Hurtado I, Zapater P, Bellot P, et al. Interleukin-10-mediated heme oxygenase 1-induced underlying mechanism in inflammatory down-regulation by norfloxacin in cirrhosis. Hepatology. 2011 Mar;53(3):935-44. PMID: 21374664.

Padeĭskaia EN. Norfloxacin: more than 20 years of clinical use, the results and place among fluoroquinolones in modern chemotherapy for infections. Antibiot Khimioter. 2003;48(9):28-36. PMID: 15002177.

Drlica K, Zhao X. DNA gyrase, topoisomerase IV, and the 4-quinolones. Microbiol Mol Biol Rev. 1997 Sep;61(3):377-92. PMID: 9293187.

Ho YB, Zakaria MP, Latif PA, Saari N. Occurrence of veterinary antibiotics and progesterone in broiler manure and agricultural soil in Malaysia. Sci Total Environ. 2014 Aug 1;488-489:261-267. PMID: 24836135.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • M002698

    M2698

    Dual inhibitor of p70S6K and Akt.

    ≥99%
  • E7357

    Esomeprazole Potassium

    (S) isomer of omeprazole; H+/K+ ATPase and MAO-...

    ≥98%
  • E6996

    Erythromycin Thiocyanate

    Macrolide; protein translation inhibitor, mamma...

    ≥90%
  • L9602

    LY-2874455

    FGFR inhibitor.

    ≥98%
  • U6873

    Ursodeoxycholic Acid

    Endogenous secondary bile acid.

    ≥98%
  • G4634

    Glipizide

    Sulfonylurea; ATP-sensitive K+ channel blocker....

    ≥98%
  • D183734

    7-O-Desmethyl Rapamycin

    Rapamycin impurity

    ≥85%
  • T3039

    Thienyloctyl Isothiocyanate

    Thienylbutyl ITC analog.

    ≥97%
  • A5039

    Amitraz

    Insecticide; α-adrenergic agonist, MAO inhibit...

    ≥97%
  • P5745

    Polygalic Acid

    Saponin found in Polygala.

    ≥97%
  • C0033

    Cafestol Stearate

    Diterpene found in brewed, unfiltered coffee; F...

    ≥98%
  • R0154

    Ranolazine Dihydrochloride

    Nav1.7 and Nav1.8 N1+ channel blocker.

    ≥98%
  • E7209

    Escitalopram Oxalate

    S-enantiomer of citalopram; SERT inhibitor.

    ≥99%
  • L1761

    Leptomycin B

    Polyketide; CRM1 inhibitor.

    ≥98%
  • S8147

    Sulindac Sulfide

    NSAID; COX-1/2 and PDE inhibitor.

    ≥98%
  • M1744

    Melittin

    Antimicrobial peptide found in Apis mellifera.<...

    ≥95%
  • P4492

    PLX4720

    V600E B-Raf inhibitor.

    ≥98%
  • P3209

    Piceatannol

    Polyphenolic hydroxystilbene, resveratrol deri...

    ≥99%
  • C0274

    Caspofungin Diacetate

    Lipopeptide; 1,3-β-Glucan synthase inhibitor.<...

    ≥95%
  • A6934

    Aristolochic Acid C

    Found in Aristolochia and Radix; potential PLA2...

    ≥94%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only