• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Palomid 529

Palomid 529

Product ID P0246
Cas No. 914913-88-5
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $63.60 In stock
5 mg $211.50 In stock
10 mg $339.40 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Palomid 529 inhibits mTORC1/2 and exhibits anticancer chemotherapeutic and anti-angiogenic activities. Palomid 529 is currently in clinical trials as a potential treatment for macular degeneration. In mice with BRCA-1-deficient breast cancer tumors, palomid 529 inhibits tumor growth. Palomid 529 also inhibits angiogenesis and vascular permeability in cellular models. Additionally, palomid 529 indirectly inhibits downstream Akt signaling.

Product Info

Cas No.

914913-88-5

Purity

≥98%

Formula

C24H22O6

Formula Wt.

406.43

IUPAC Name

8-(1-hydroxyethyl)-2-methoxy-3-[(4-methoxyphenyl)methoxy]benzo[c]chromen-6-one

Synonym

P529

Solubility

DMSO 81 mg/mL (199.29 mM) Water Insoluble Ethanol Insoluble

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

P0246 MSDS PDF

Info Sheet

P0246 Info Sheet PDF

Brochures

PI3K-Akt-mTORC Pathway Booklet

References

Dalal M, Jacobs-El N, Nicholson B, et al. Subconjunctival Palomid 529 in the treatment of neovascular age-related macular degeneration. Graefes Arch Clin Exp Ophthalmol. 2013 Dec;251(12):2705-9. PMID: 23689994.

Xiang T, Jia Y, Sherris D, et al. Targeting the Akt/mTOR pathway in Brca1-deficient cancers. Oncogene. 2011 May 26;30(21):2443-50. PMID: 21242970.

Xue Q, Hopkins B, Perruzzi C, et al. Palomid 529, a novel small-molecule drug, is a TORC1/TORC2 inhibitor that reduces tumor growth, tumor angiogenesis, and vascular permeability. Cancer Res. 2008 Nov 15;68(22):9551-7. PMID: 19010932.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • C0148

    Calcitonin, human

    Endogenous neuropeptide hormone, lowers extrace...

    ≥95%
  • K0023

    K252c

    Staurosporine analog; PKC and PKA inhibitor.

    ≥98%
  • I5992

    IOX2

    Prolyl hydroxylase inhibitor.

    ≥98%
  • C0251

    Calcitonin Gene Related Peptide II, rat

    Calcitonin-family peptide, involved in vasodila...

    ≥95%
  • A5478

    Antipain Dihydrochloride

    Oligopeptide found in Actinomycetes; protease i...

  • P014442

    Palbociclib

    CDK4/6 inhibitor.

    ≥98%
  • C8070

    Curcumin, high purity

    Active compound found in turmeric; MST1 activat...

    ≥98%
  • B030966

    BAY 11-7082

    inhibits inflammatory signaling

    ≥98%
  • C0162

    Capecitabine

    5-FU prodrug; thymidylate synthase inhibitor.

    ≥98%
  • C2818

    Chelerythrine Chloride

    benzophenanthridine alkaloid found in Chelidoni...

    ≥98%
  • I7757

    Itopride Hydrochloride

    AChE inhibitor, D2 antagonist.

    ≥98%
  • A464766

    Altenuene

    Alternaria mycotoxin which may be found in food...

    ≥98%
  • C6982

    Crustacean Cardioactive Peptide

    Neuropeptide hormone found in arthropods.

    ≥95%
  • B4514

    Bleomycin A5 Hydrochloride Cu

    Induces apoptosis, DNA cleavage and strand brea...

    ≥85%
  • W0275

    R-(+)-Warfarin Sodium >99%ee

    Coumarin; VKORC1 inhibitor.

    ≥99%
  • F0275

    Fasudil Hydrochloride

    ROCK inhibitor.

    ≥98%
  • P7012

    Prednisolone Sodium Phosphate

    Water-soluble cortisol derivative; glucocortico...

    ≥98%
  • M578522

    Monascin

    Fungal pigment found in red yeast rice

    ≥98%
  • M1879

    Metoprolol Tartrate

    β1-adrenergic antagonist.

    ≥98%
  • A528251

    Angiotensin I/II (1-7)(DP-7)

    Peptide fragment

    ≥95%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only