• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Palomid 529

Palomid 529

Product ID P0246
Cas No. 914913-88-5
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $63.60 In stock
5 mg $211.50 In stock
10 mg $339.40 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Palomid 529 inhibits mTORC1/2 and exhibits anticancer chemotherapeutic and anti-angiogenic activities. Palomid 529 is currently in clinical trials as a potential treatment for macular degeneration. In mice with BRCA-1-deficient breast cancer tumors, palomid 529 inhibits tumor growth. Palomid 529 also inhibits angiogenesis and vascular permeability in cellular models. Additionally, palomid 529 indirectly inhibits downstream Akt signaling.

Product Info

Cas No.

914913-88-5

Purity

≥98%

Formula

C24H22O6

Formula Wt.

406.43

IUPAC Name

8-(1-hydroxyethyl)-2-methoxy-3-[(4-methoxyphenyl)methoxy]benzo[c]chromen-6-one

Synonym

P529

Solubility

DMSO 81 mg/mL (199.29 mM) Water Insoluble Ethanol Insoluble

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

P0246 MSDS PDF

Info Sheet

P0246 Info Sheet PDF

Brochures

PI3K-Akt-mTORC Pathway Booklet

References

Dalal M, Jacobs-El N, Nicholson B, et al. Subconjunctival Palomid 529 in the treatment of neovascular age-related macular degeneration. Graefes Arch Clin Exp Ophthalmol. 2013 Dec;251(12):2705-9. PMID: 23689994.

Xiang T, Jia Y, Sherris D, et al. Targeting the Akt/mTOR pathway in Brca1-deficient cancers. Oncogene. 2011 May 26;30(21):2443-50. PMID: 21242970.

Xue Q, Hopkins B, Perruzzi C, et al. Palomid 529, a novel small-molecule drug, is a TORC1/TORC2 inhibitor that reduces tumor growth, tumor angiogenesis, and vascular permeability. Cancer Res. 2008 Nov 15;68(22):9551-7. PMID: 19010932.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • F8149

    Fumonisin B1

    Mycotoxin produced by Fusarium; sphingosine acy...

    ≥98%
  • D5992

    Doxapram Hydrochloride Hydrate

    K+ channel blocker, catecholamine release stimu...

    ≥98%
  • S6235

    Spironolactone

    Mineralocorticoid, aldosterone, AR antagonist, ...

    ≥97%
  • C2997

    Chymostatin

    Protease inhibitor.

    ≥95% (mixture of A, B, C)
  • A0965

    Adrenocorticotropic Hormone (1-14)

    Endogenous peptide hormone fragment, involved i...

    ≥95%
  • Z3463

    Ziprasidone

    5-HT1A agonist, D2, 5-HT1D antagonist.

    ≥98%
  • C0366

    Carvedilol Phosphate Hemihydrate

    FIASMA; α1- and β1/2-adrenergic antagonist.

    ≥98%
  • S0278

    Satraplatin

    Pt-based DNA cross-linker.

    ≥98%
  • R0348

    Ramelteon

    Melatonin analog; MT1/2 agonist.

    ≥99%
  • S0930

    Schisantherin A

    Dibenzocyclooctadiene found in Schisandra.

    ≥98%
  • I5315

    Indomethacin

    NSAID; COX-1/2 inhibitor.

    ≥98%
  • C1868

    Cerebellin

    Peptide, involved in synapse formation and cell...

    ≥95%
  • P0013

    P7C3

    Aminopropyl carbazole, neuroprotective.

    ≥98%
  • R2816

    Recombinant HIV-2 gp36

    Recombinant HIV-1 glycoprotein antigen fragment...

    ≥95%
  • D5612

    2-n-Dodecylfuran

    Furan derivative.

    ≥98%
  • C2947

    Chlorpromazine Hydrochloride

    Phenothiazine, FIASMA; D1/2/3/4, 5-HT1/2, M1/2 ...

    ≥98%
  • G1745

    Gemcitabine Hydrochloride

    Nucleoside (deoxycytidine) analog; ribonucleoti...

    ≥98%
  • P0110

    (R)-P7C3-OMe

    Methoxy aminopropyl carbazole, neuroprotective....

    ≥98%
  • E846184

    Everolimus EP Impurity B

    Everolimus impurity

    ≥96% (mix of E/Z)
  • M3310

    Miconazole Nitrate

    Imidazole; 14-α demethylase inhibitor, potenti...

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only