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Pancreatic Polypeptide, human

Pancreatic Polypeptide, human

Product ID P0353
Cas No. 75976-10-2
Purity ≥98%
Product Unit SizeCostQuantityStock
0.5 mg $278.00 Please Inquire
1 mg $474.20 Please Inquire
2.5 mg $834.40 Please Inquire
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Pancreatic polypeptide is an endogenous neuropeptide Y-family hormone that exhibits anorexigenic activity. Pancreatic polypeptide binds the Y4 receptor to decrease food intake, increase locomotor activity, and stimulate colonic muscle contractions and transit. Decreased secretion of pancreatic polypeptide is associated with improvements in pancreatic β-cell function in subjects with type 2 diabetes.

Product Info

Cas No.

75976-10-2

Purity

≥98%

Formula

C185H286N53O54S2

Formula Wt.

4181.7

Solubility

Soluble in water (0.7 mg/mL).

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

P0353 MSDS PDF

Info Sheet

P0353 Info Sheet PDF

References

Kahleova H, Mari A, Nofrate V, et al. Improvement in β-cell function after diet-induced weight loss is associated with decrease in pancreatic polypeptide in subjects with type 2 diabetes. J Diabetes Complications. 2012 Sep-Oct;26(5):442-9. PMID: 22673566.

Hankir MK, Parkinson JR, Minnion JS, et al. Peptide YY 3-36 and pancreatic polypeptide differentially regulate hypothalamic neuronal activity in mice in vivo as measured by manganese-enhanced magnetic resonance imaging. J Neuroendocrinol. 2011 Apr;23(4):371-80. PMID: 21251093.

Moriya R, Fujikawa T, Ito J, et al. Pancreatic polypeptide enhances colonic muscle contraction and fecal output through neuropeptide Y Y4 receptor in mice. Eur J Pharmacol. 2010 Feb 10;627(1-3):258-64. PMID: 19818748.

Liu YL, Semjonous NM, Murphy KG, et al. The effects of pancreatic polypeptide on locomotor activity and food intake in mice. Int J Obes (Lond). 2008 Nov;32(11):1712-5. PMID: 18779824.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

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