• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Pimobendan

Pimobendan

Product ID P3456
Cas No. 74150-27-9
Purity ≥99%
Product Unit SizeCostQuantityStock
10 mg $68.30 In stock
25 mg $89.30 In stock
100 mg $189.00 In stock
500 mg $367.50 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Pimobendan is a cardiovascular drug commonly used to treat congestive heart failure, dilated cardiomyopathy, and chronic valvular heart disease in veterinary medicine. This compound exhibits vasodilatory and antithrombotic activities, decreasing peripheral resistance and inhibiting platelet aggregation. Pimobendan selectively inhibits cardiac phosphodiesterase III (PDE3), increasing myocardial cAMP and causing positive inotropic effects such as an increase in heart rate, left ventricle systolic pressure, and left ventricle filling pressure, and a decrease in peripheral resistance (mean arterial pressure).

Product Info

Cas No.

74150-27-9

Purity

≥99%

Formula

C19H18N4O2

Formula Wt.

334.37

Chemical Name

3-[2-(4-methoxyphenyl)-3H-benzimidazol-5-yl]-4-methyl-4, 5-dihydro-1H-pyridazin-6-one

IUPAC Name

3-[2-(4-methoxyphenyl)-3H-benzimidazol-5-yl]-4-methyl-4, 5-dihydro-1H-pyridazin-6-one

Synonym

Acardi, pimobendane

Solubility

DMSO 67 mg/mL; Water <1 mg/mL; Ethanol 5 mg/mL

Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

P3456 MSDS PDF

Info Sheet

P3456 Info Sheet PDF

References

Shipley EA, Hogan DF, Fiakpui NN, et al. In vitro effect of pimobendan on platelet aggregation in dogs. Am J Vet Res. 2013 Mar;74(3):403-7. PMID: 23438115.

Boyle KL, Leech E. A review of the pharmacology and clinical uses of pimobendan. J Vet Emerg Crit Care (San Antonio). 2012 Aug;22(4):398-408. PMID: 22928748.

Verdouw PD, Hartog JM, Duncker DJ, et al. Cardiovascular profile of pimobendan, a benzimidazole-pyridazinone derivative with vasodilating and inotropic properties. Eur J Pharmacol. 1986 Jul 15;126(1-2):21-30. PMID: 2875884.

Scholz H, Meyer W. Phosphodiesterase-inhibiting properties of newer inotropic agents. Circulation. 1986 Mar;73(3 Pt 2):III99-108. PMID: 2417748.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • C179602

    CEP-28122

    ALK inhibitor.

    ≥98%
  • K1978

    Ketorolac Tromethamine

    NSAID; COX-1/2 inhibitor.

    ≥98%
  • C0251

    Calcitonin Gene Related Peptide II, rat

    Calcitonin-family peptide, involved in vasodila...

    ≥95%
  • S8009

    Substance P (7-11)

    Endogenous tachykinin peptide, involved in infl...

    ≥95%
  • C0275

    Castanospermine

    O-GlcNAcase inhibitor.

    ≥98%
  • S3353

    Sinomenine Hydrochloride

    Alkaloid found in Sinomenium; acid-sensing ion ...

    ≥98%
  • S8049

    S-Sulforaphene

    Isothiocyanate found in cruciferous vegetables....

    ≥98%
  • M185777

    4-(Methylsulfinyl) butylamine

    ≥99%
  • A2056

    Aflatoxin Q1

    Mycotoxin metabolite

    ≥98%
  • L9600

    LY-2090314

    GSK-3 inhibitor.

    ≥98%
  • N5767

    Norethindrone

    Steroid hormone, contraceptive; PR agonist.

    ≥98%
  • S7970

    Strontium Ranelate

    Bone deterioration inhibitor, potential CaR ago...

    ≥98%
  • C0267

    Carnosol

    Diterpene compound originally found in Rosmarin...

    ≥98%
  • A0501

    Abamectin

    Macrocyclic lactone avermectin; GABA antagonist...

    ≥70%
  • A0922

    Acetyl-L-Carnitine Hydrochloride

    Carnitine derivative, involved in energy homeos...

    ≥98%
  • H9717

    Hydroxyzine Dihydrochloride

    FIASMA, histamine H1 inverse agonist, 5-HT2A, D...

    ≥98%
  • M1770

    Meropenem Sodium Carbonate

    Carbapenem β-lactam; penicillin binding protei...

    ≥98%
  • R2917

    Rhein

    Diacerein metabolite, anthraquinone found in Rh...

    ≥88%
  • G7242

    GSK-690693

    Akt inhibitor.

    ≥99%
  • M1335

    Mdivi-1

    Quinazolinone; mitochondrial division inhibitor...

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only