LKT Labs

Biochemicals for Life Science Research

Pituitary Adenylate Cyclase-activating Polypeptide-related Peptide, rat

Pituitary Adenylate Cyclase-activating Polypeptide-related Peptide, rat

Product ID P0011
Cas No.
Purity ≥95%
Product Unit SizeCostQuantityStock
0.5 mg $94.50 Please Inquire
1 mg $157.50 Please Inquire
2.5 mg $315.00 Please Inquire
Bulk Quote

Quicklinks

Description

Pituitary adenylate cyclase-activating polypeptide (PACAP) stimulates cAMP production in the anterior pituitary. PACAP and PACAP-related peptide (PRP) regulate immune function and display increases in expression when hosts are challenged with bacterial pathogens. PACAP and PRP also control expression of reproductive hormones such as follicle-stimulating hormone (FSH) and luteinizing hormone (LH). Additionally, PACAP and PRP bind the PAC1 receptor and VPAC1/2 receptors. PACAP itself inhibits K+ amplitude of delayed rectifier K+ channels, exhibiting anti-apoptotic activity in cerebellar granule cells.

Product Info

Purity

≥95%
Formula

C148H242N42O45S
Formula Wt.

3361.87
Synonym

PACAP-related peptide (1-19), rat, PRP

Shipping and Storage

Store Temp

-20°C
Ship Temp

Ambient

Downloads

MSDS

P0011 MSDS PDF
Info Sheet

P0011 Info Sheet PDF

References

Nam BH, Moon JY, Kim YO, et al. Structural and functional characterization of pituitary adenylyl cyclase-activating polypeptide (PACAP)/PACAP-related peptide (PRP) and its receptor in olive flounder (Paralichthys olivaceus). Comp Biochem Physiol B Biochem Mol Biol. 2013 Jan;164(1):18-28. PMID: 23026070.

Tam JK, Lee LT, Cheng CH, et al. Discovery of a new reproductive hormone in teleosts: pituitary adenylate cyclase-activating polypeptide-related peptide (PRP). Gen Comp Endocrinol. 2011 Sep 15;173(3):405-10. PMID: 21703272.

Vaudry D, Falluel-Morel A, Bourgault S, et al. Pituitary adenylate cyclase-activating polypeptide and its receptors: 20 years after the discovery. Pharmacol Rev. 2009 Sep;61(3):283-357. PMID: 19805477.

Mei YA, Vaudry D, Basille M, et al. PACAP inhibits delayed rectifier potassium current via a cAMP/PKA transduction pathway: evidence for the involvement of I k in the anti-apoptotic action of PACAP. Eur J Neurosci. 2004 Mar;19(6):1446-58. PMID: 15066141.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • P0369

    Parecoxib Sodium

    NSAID; COX-2 inhibitor.

    ≥99%
  • D019601

    Dapagliflozin

    SGLT2 inhibitor

    ≥98%
  • S0245

    Salmeterol

    β2-adrenergic agonist.

    ≥98%
  • A4646

    ALLN

    Calpain I/II inhibitor.

    ≥98%
  • W317520

    WIN 55,212-2 Mesylate

    Non-selective cannabinoid receptor agonist.

    ≥98%
  • A121008

    Adagrasib

    KRAS inhibitor

    ≥99%
  • C9611

    Cyclosporin A

    Cyclic peptide; calcineurin inhibitor.

    ≥98%
  • N8660

    NVP-AUY922

    Isoxazole derivative; HSP90 inhibitor.

    ≥98%
  • C5592

    CNX-774

    BTK inhibitor.

    ≥98%
  • A480000

    AM251

    CB1 receptor antagonist/ inverse agonist.

    ≥97%
  • T7037

    Triptorelin Acetate

    Peptide, GnRH analog.

    ≥95%
  • A5032

    D,L-Aminoglutethimide

    Aromatase inhibitor.

    ≥98%
  • P200091

    PF-07104091

    CDK2 inhibitor

    ≥98%
  • R2400

    RG-108

    DNMT inhibitor.

    ≥98%
  • A2500

    AG-1478

    EGFR inhibitor.

    ≥98%
  • B8363

    Bupropion Hydrochloride

    α3β2, α3β4, α4β2 nAChR antagonist, indire...

    ≥98%
  • E6994

    Erythromycin

    Macrolide; protein translation inhibitor, mamma...

    ≥94%
  • U6860

    Urocortin III, mouse

    Endogenous peptide, involved in stress signalin...

    ≥95%
  • M1875

    S-(N-Methylsulfinylbutylthiocarbamoyl)-glutathione

    Glutathione-sulforaphane conjugate, antioxidant...

    ≥98%
  • P0246

    Palomid 529

    mTOR inhibitor.

    ≥98%