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PluriSIn 1

PluriSIn 1

Product ID P4782
Cas No. 91396-88-2
Purity ≥98%
Product Unit SizeCostQuantityStock
5 mg $92.70 In stock
10 mg $155.20 In stock
25 mg $320.90 In stock
50 mg $498.10 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

PluriSin 1 is a pluripotent cell-specific inhibitor that induces endoplasmic reticular stress and apoptosis in pluripotent stem cells. This compound inhibits stearoyl-coA desaturase 1 (SCD1), preventing teratoma formation in tumorigenic undifferentiated cells. Plurisin1 prevents undifferentiated cells from developing into tumors when used to regenerate tissues such as the heart.

Product Info

Cas No.

91396-88-2

Purity

≥98%

Formula

C12H11N3O

Formula Wt.

213.24

IUPAC Name

N'-Phenylisonicotinohydrazide

Synonym

NSC 14613, PluriSln 1, Isonicotinic Acid 2-Phenylhydrazide, Plurisin #1

Solubility

10mM in DMSO

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

P4782 MSDS PDF

Info Sheet

P4782 Info Sheet PDF

References

Zhang L, Pan Y, Qin G, et al. Inhibition of stearoyl-coA desaturase selectively eliminates tumorigenic Nanog-positive cells: improving the safety of iPS cell transplantation to myocardium. Cell Cycle. 2014;13(5):762-71. PMID: 24394703.

Ben-David U, Gan QF, Golan-Lev T, et al. Selective elimination of human pluripotent stem cells by an oleate synthesis inhibitor discovered in a high-throughput screen. Cell Stem Cell. 2013 Feb 7;12(2):167-79. PMID: 23318055.

Custom Order

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