Description
Prolylrapamycin is a derivative of the antifungal antibiotic, rapamycin, a secondary metabolite produced by Streptomyces hygroscopicus.
| Product Unit Size | Cost | Quantity | Stock |
|---|
Prolylrapamycin is a derivative of the antifungal antibiotic, rapamycin, a secondary metabolite produced by Streptomyces hygroscopicus.
| Cas No. | 156223-31-3 |
|---|---|
| Formula | C50H77NO13 |
| Formula Wt. | 900.16 |
| Chemical Name | Prolylrapamycin |
| IUPAC Name | (15E,23E,25E,27E)-1,17-dihydroxy-11-[1-(4-hydroxy-3-methoxycyclohexyl)propan-2-yl]-18,29-dimethoxy-14,16,20,22,28,34-hexamethyl-10,35-dioxa-4-azatricyclo[29.3.1.04,8]pentatriaconta-15,23,25,27-tetraene-2,3,9,13,19-pentone |
| Synonym | Prolyl Rapamycin; Dihydroxy-[2-(4-hydroxy-3-methoxy-cyclohexyl)-1-methyl-ethyl]-dimethoxy-hexamethyl-[?]pentone, prolyl sirolimus; 21-Norrapamycin |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| Info Sheet |
|---|
G K Wong , S Griffith, I Kojima, A L Demain, Antifungal activities of rapamycin and its derivatives, prolylrapamycin, 32-desmethylrapamycin, and 32-desmethoxyrapamycin. . Antibiot (Tokyo) 51(5):487-91. PMID: 9666177 DOI: 10.7164/antibiotics.51.487
Taxol derivative.
pan-PI3K inhibitor.
Toll-like receptor 7/8 agonist
Electrophile used in 2’-hydroxyl acylation of...
Endogenous peptide, involved in hormone regulat...
Survivin inhibitor.
Cannabinoid receptor 2 selective agonist.
5-Lipoxygenase inhibitor.
Iridoid glycoside found in Gardenia.
LRRK2 inhibitor.
Indoleamine 2,3-dioxygenase inhibitor.
Acyl-CoA synthetase inhibitor.
Found in Polygata tennifolia.
Protein synthesis inhibitor, used to measure pr...
Alkaloid found in black and long peppers; TRPV1...
Histamine H1-antagonist
MEK1/2 and ERK inhibitor.
Oxazolidinone; protein synthesis inhibitor.
JAK3 and EGFR inhibitor.
Tropane alkaloid found in Solanaceae plants; M1...