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Prothionamide

Prothionamide

Product ID P6959
Cas No. 14222-60-7
Purity ≥98%
Product Unit SizeCostQuantityStock
1 g $102.00 In stock
5 g $163.40 Please Inquire
25 g $510.50 Please Inquire
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Prothionamide is an antibacterial compound that is clinically used to treat Mycobacterium-based diseases such as tuberculosis and leprosy. Prothionamide forms adducts with nicotinamide adenine dinucleotide (NAD), inhibiting InhA and preventing synthesis of mycoloic acids.

Product Info

Cas No.

14222-60-7

Purity

≥98%

Formula

C9H12N2S

Formula Wt.

180.27

Chemical Name

2-Propyl-4-pyridinecarbothioamide

IUPAC Name

2-propylpyridine-4-carbothioamide

Synonym

Protionamide, Ektebin, Tuberex, Peteha, Trevintix

Melting Point

142°C

Solubility

Soluble in ethanol and methanol. Slightly soluble in ether and chloroform. Insoluble in water.

Appearance

A Yellow Crystalline Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

P6959 MSDS PDF

Info Sheet

P6959 Info Sheet PDF

References

Shim TS, Jo KW. Medical Treatment of Pulmonary Multidrug-Resistant Tuberculosis. Infect Chemother. 2013 Dec;45(4):367-374. PMID: 24475350.

Wang F, Langley R, Gulten G, et al. Mechanism of thioamide drug action against tuberculosis and leprosy. J Exp Med. 2007 Jan 22;204(1):73-8. PMID: 17227913.

Fajardo TT, Guinto RS, Cellona RV, et al. A clinical trial of ethionamide and prothionamide for treatment of lepromatous leprosy. Am J Trop Med Hyg. 2006 Mar;74(3):457-61. PMID: 16525107.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
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