• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Quinacrine Dihydrochloride Dihydrate

Quinacrine Dihydrochloride Dihydrate

Product ID Q8133
Cas No. 6151-30-0
Purity ≥97%
Product Unit SizeCostQuantityStock
1 g $45.30 In stock
5 g $90.30 In stock
10 g $160.50 In stock
25 g $337.10 Please Inquire
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Quinacrine exhibits anti-parasitic, anti-protozoan, anticancer, and anti-inflammatory activities. Quinacrine alters cell membrane permeability and is clinically used to treat infections of Giardia. In colon cancer cells, quinacrine induces apoptosis, activates p53 and p21, and inhibits topoisomerase. In other cellular models, quinacrine decreases TNF-α, IL-1β, and CCL21 production, suppresses migration of dendritic cells, and inhibits activation of CD8+ T cells.

Product Info

Cas No.

6151-30-0

Purity

≥97%

Formula

C23H30ClN3O • 2HCl • 2H2O

Formula Wt.

508.92

Chemical Name

N4-(6-Chloro-2-methoxy-9-acridinyl)-N1,N1-diethyl-1,-4-pentanediamine dihydrochloride dihydrate

IUPAC Name

4-N-(6-chloro-2-methoxyacridin-9-yl)-1-N,1-N-diethylpentane-1, 4-diamine;dihydrate;dihydrochloride

Synonym

Atebrine hydrochloride, RP-866, SN-390, Mepacrine

Melting Point

248-250°C(dec)

Solubility

Soluble in hot water. Slightly soluble in ethanol, methanol or water. Insoluble in ether, benzene or acetone.

Appearance

Bright yellow powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

Q8133 MSDS PDF

Info Sheet

Q8133 Info Sheet PDF

References

Mohapatra P, Preet R, Das D, et al. Quinacrine-mediated autophagy and apoptosis in colon cancer cells is through a p53- and p21-dependent mechanism. Oncol Res. 2012;20(2-3):81-91. PMID: 23193914.

Gorbachev AV, Gasparian AV, Gurova KV, et al. Quinacrine inhibits the epidermal dendritic cell migration initiating T cell-mediated skin inflammation. Eur J Immunol. 2007 Aug;37(8):2257-67. PMID: 17634953.

Fasanmade AA, Owuor ED, Ee RP, et al. Quinacrine induces cytochrome c-dependent apoptotic signaling in human cervical carcinoma cells. Arch Pharm Res. 2001 Apr;24(2):126-35. PMID: 11339632.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • K0054

    Kanamycin B

    Aminoglycoside; protein translation inhibitor, ...

    ≥98%
  • Z2268

    Z-FR-AMC

    Protease substrate.

    ≥95%
  • P3209

    Piceatannol

    Polyphenolic hydroxystilbene, resveratrol deri...

    ≥99%
  • A6058

    Apoptosis Activator 2

    Apoptosis inducing agent.

    ≥98%
  • V182685

    Verdinexor

    CRM1/XPO1 inhibitor.

    ≥99%
  • A5276

    Angiotensin I, human

    Endogenous peptide, cleavage product of angiote...

    ≥98%
  • P7718

    Pterostilbene

    Stilbene, resveratrol analog.

    ≥98%
  • C9709

    Cycloheximide

    Protein synthesis inhibitor, used to measure pr...

    ≥98%
  • B3577

    Bitertanol

    Pesticide; demethylation inhibitor.

    ≥98%
  • E6376

    Eptifibatide

    Glycoprotein IIb/IIIa inhibitor.

    ≥98%
  • X4424

    XL-765

    PI3K and mTOR inhibitor.

    ≥98%
  • A5282

    [Sar1 Ile8]-Angiotensin II

    Peptide, derivative of AT II, involved in vasoc...

    ≥95%
  • M1746

    Melphalan

    Nitrogen mustard, DNA alkylator.

    ≥95%
  • K0053

    Kanamycin A Monosulfate

    Aminoglycoside; protein translation inhibitor, ...

    ≥98%
  • L3561

    D,L-α-Lipoic Acid

    Endogenous organosulfur also found in meat and ...

    ≥99%
  • T5672

    Tosufloxacin Tosylate

    Fluoroquinolone; topoisomerase IV and bacterial...

    ≥98%
  • M4200

    MK-0752

    γ-Secretase inhibitor.

    ≥98%
  • C9610

    D-Cycloserine

    NMDA partial agonist, D-Ala-D-Ala ligase inhibi...

    ≥98%
  • D3372

    Disodium Cycloheptylaminomethylene Diphosphate

    Bisphosphonate; squalene synthase inhibitor.

    ≥98%
  • H1794

    Hexamethonium Bromide Hydrate

    Non-depolarizing NMJ blocker; nAChR antagonist....

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only