Name: Ridaifen A Dihydrochloride
SKU: R3312
Availability: InStock

Description

Ridaifen A is a tamoxifen derivative. Like other ridaifens, ridaifen A may exhibit anticancer activity. Related compound ridaifen B increases ROS levels and mitochondria-mediated apoptosis in breast cancer cells. Related compound ridaifen F inhibits the proteasome.

Product Info

Purity	≥98%
Formula	C₃₀H₃₈N₂O₂ • 2HCl
Formula Wt.	531.56
Appearance	White to off white powder

Shipping and Storage

Store Temp	Ambient
Ship Temp	Ambient

Downloads

MSDS	R3312 MSDS PDF
Info Sheet	R3312 Info Sheet PDF

References

Hasegawa M, Yasuda Y, Tanaka M, et al. A novel tamoxifen derivative, ridaifen-F, is a nonpeptidic small-molecule proteasome inhibitor. Eur J Med Chem. 2013 Nov 16;71C:290-305. PMID: 24321833.

Guo WZ, Shiina I, Wang Y, et al. Ridaifen-SB8, a novel tamoxifen derivative, induces apoptosis via reactive oxygen species-dependent signaling pathway. Biochem Pharmacol. 2013 Nov 1;86(9):1272-84. PMID: 23973528.

Nagahara Y, Shiina I, Nakata K, et al. Induction of mitochondria-involved apoptosis in estrogen receptor-negative cells by a novel tamoxifen derivative, ridaifen-B. Cancer Sci. 2008 Mar;99(3):608-14. PMID: 18167132.

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Ridaifen A Dihydrochloride

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