Description
Sofosbuvir is an antiviral compound that inhibits viral RNA polymerase. Sofosbuvir is clinically used to treat hepatitis C infection. This compound is a prodrug that is metabolized to a more active intermediate.
Product Unit Size | Cost | Quantity | Stock |
---|
Sofosbuvir is an antiviral compound that inhibits viral RNA polymerase. Sofosbuvir is clinically used to treat hepatitis C infection. This compound is a prodrug that is metabolized to a more active intermediate.
Cas No. | 1190307-88-0 |
---|---|
Purity | ≥98% |
Formula | C22H29FN3O9P |
Formula Wt. | 529.45 |
IUPAC Name | propan-2-yl (2S)-2-[[[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyloxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate |
Solubility | DMSO 100 mg/mL warmed (188.87 mM) Ethanol 100 mg/mL (188.87 mM) Water 11 mg/mL warmed (20.77 mM) |
Appearance | Yellow to off white powder |
Store Temp | Ambient |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Murakami C, Melda Urekli H, Atta MG. Antiviral medications for the treatment of hepatitis B and C infection and their effects on kidney function. Minerva Gastroenterol Dietol. 2014 Sep;60(3):177-89. PMID: 25027705.
Fung A, Jin Z, Dyatkina N, et al. Efficiency of incorporation and chain termination determines the inhibition potency of 2'-modified nucleotide analogs against hepatitis C virus polymerase. Antimicrob Agents Chemother. 2014 Jul;58(7):3636-45. PMID: 24733478.
Murakami E, Tolstykh T, Bao H, et al. Mechanism of activation of PSI-7851 and its diastereoisomer PSI-7977. J Biol Chem. 2010 Nov 5;285(45):34337-47. PMID: 20801890.
Lectin found in Canavelia, plant mitogen that b...
β-lactam cephalosporin; penicillin binding pro...
Endogenous peptide hormone; CCK2 agonist, indir...
5-HT7 and D2/3 antagonist.
Triterpenoid found in Vigna angularis and Trigo...
Peptide, contains two cell-penetrating sequence...
Abl (T315I) inhibitor.
SIRT1/2 inhibitor, indirect p53 activator.
Cdc7 inhibitor.
Nitroimidazole; hypoxic modifier and radiosensi...
TRPA1 antagonist
VEGFR1/2/3, TIE2, PDGFRβ, FGFR1, c-Kit, RET, B...
Cannabinoid receptor 2 selective agonist.
Hydrazine derivative, DNA alkylator; MAO inhibi...
H1 histamine and LT antagonist, PDE inhibitor.<...
STING agonist
SRPK1 inhibitor.
Tetrapeptide, binds cell surface integrins.
FAAH inhibitor.
Benzylpiperidine; AMPA potentiator.