• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Strontium Ranelate

Strontium Ranelate

Product ID S7970
Cas No. 135459-87-9
Purity ≥98%
Product Unit SizeCostQuantityStock
100 mg $61.40 In stock
1 g $125.80 In stock
5 g $275.60 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Strontium ranelate (SR) prevents deterioration of bone tissue microarchitecture in osteoporosis. When used clinically to prevent osteoporosis, SR stimulates pre-osteoblast replication and decreases osteoclast activity, increasing the ultimate load of intact bones, making them stiffer, harder, and tougher. In vitro, SR inhibited activation of NF-κB, promoting osteoblast differentiation and suppressing osteoclast formation. In other cellular models, SR stimulates phosphorylation of ERK and increases expression of osteocalcin and bone morphogenetic protein 2 (BMP2), potentially through activation of calcium-sensing receptor CaR.

Product Info

Cas No.

135459-87-9

Purity

≥98%

Formula

C12H6N2O8S • Sr2

Formula Wt.

513.49

Chemical Name

distrontium;5-[bis(carboxylatomethyl)amino]-3-(carboxylatomethyl)-4-cyanothiophene-2-carboxylate

IUPAC Name

distrontium;5-[bis(carboxylatomethyl)amino]-3-(carboxylatomethyl)-4- cyanothiophene-2-carboxylate

Synonym

Protelos, distrontium renelate, Protos

Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

S7970 MSDS PDF

Info Sheet

S7970 Info Sheet PDF

References

Cattani-Lorente M, Rizzoli R, Ammann P. In vitro bone exposure to strontium improves bone material level properties. Acta Biomater. 2013 Jun;9(6):7005-13. PMID: 23454213.

Rodríguez J, Escudero ND, Mandalunis PM. Effect of strontium ranelate on bone remodeling. Acta Odontol Latinoam. 2012;25(2):208-13. PMID: 23230643.

Yamaguchi M, Weitzmann MN. The intact strontium ranelate complex stimulates osteoblastogenesis and suppresses osteoclastogenesis by antagonizing NF-κB activation. Mol Cell Biochem. 2012 Jan;359(1-2):399-407. PMID: 21874315.

Takaoka S, Yamaguchi T, Yano S, et al. The Calcium-sensing Receptor (CaR) is involved in strontium ranelate-induced osteoblast differentiation and mineralization. Horm Metab Res. 2010 Aug;42(9):627-31. PMID: 20560105.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • G337543

    Ginsenoside CK

    Major metabolite of ginsenosides Rb1, Rb2, Rc, ...

    ≥98%
  • T2800

    Thalidomide

    Immunomodulator; teratogen.

    ≥98%
  • A4577

    Alsterpaullone

    GSK-3 and CDK inhibitor.

    ≥98%
  • P691320

    PRI-724

    Wnt/beta-catenin/CBP inhibitor

    ≥98%
  • A1368

    Adrenomedullin (1-52), human

    Endogenous peptide hormone, involved in cell gr...

    ≥95%
  • N1721

    Nefiracetam

    Pyrrolidone; NMDA and mGluR5 agonist, N-type an...

    ≥98%
  • D5747

    Dolasetron Mesylate Hydrate

    5-HT3 antagonist.

    ≥98%
  • B1996

    BEZ235

    PI3K and mTOR inhibitor.

    ≥98%
  • S881011

    Swainsonine

    Antineoplastic immunomodulator.

    ≥98%
  • P2513

    Phenyl Isothiocyanate

    ITC found in cruciferous vegetables.

    ≥98%
  • N0212

    Nedaplatin

    Pt-based DNA cross-linker.

    ≥98%
  • A4445

    Allopurinol

    Purine (hypoxanthine) analog; xanthine oxidase ...

    ≥98%
  • B5044

    BML-277

    Arylbenzimidazole; CHK2 inhibitor.

    ≥98%
  • C0168

    Canthaxanthin

    Carotenoid terpene pigment found in various pla...

    ≥9% (product contains stabilizers)
  • O4102

    Okadaic Acid Ammonium

    Shellfish toxin produced by dinoflagellates and...

    ≥98%
  • T0110

    Taxane Standard Mixture

    Mixture of taxanes.

    ≥98%
  • P200091

    PF-07104091

    CDK2 inhibitor

    ≥98%
  • S9775

    Systemin

    Peptide hormone found in Solanaceae family plan...

    ≥95%
  • G0104

    Gabexate Mesylate

    Proteasome inhibitor.

    ≥99%
  • T6831

    Triadimenol

    Triadimefon metabolite; mutagen.

    ≥96%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only