Description
Sutezolid is an analog of linezolid that may be effective treatment for tuberculosis. A study using a PK/PD model has shown that sutezolid is 17-fold more potent than its metabolite U-603 against tuberculosis.
Sutezolid
Product ID S824766
Cas No. 168828-58-8
Purity ≥98%
| Product Unit Size | Cost | Quantity | Stock |
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Product Info
| Cas No. | 168828-58-8 |
|---|---|
| Purity | ≥98% |
| Formula | C16H20FN3O3S |
| Formula Wt. | 353.41 |
| Chemical Name | (S)-N-((3-(3-fluoro-4-thiomorpholinophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide |
| IUPAC Name | N-[[(5S)-3-(3-fluoro-4-thiomorpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide |
| Synonym | PNU-100480; U-100480; PF-02341272 |
Shipping and Storage
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
Downloads
| MSDS | |
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| Info Sheet |
References
Wallis R, Dawson R, Friedrich S, et al. Mycobacterial activity of sutezolid (PNU-100480) in sputum (EBA) and bloowd (WBA) of patients with pulmonary tuberculosis. PLoS One. 2014 Apr 14;9(4):e94462. PMID: 24732289.
Zhu T, Friedrich S, Diacon A, et al. Population pharmacokinetic/pharmacodynamic analysis of the bactericidal activities of sutezolid intracellular Mycobacterium tuberculosis in ex vivo whole-blood cultures of patients with pulmonary tuberculosis. Antimicrob Agents Chemother. 2014 Jun;58(6):3306-3311. PMID: 24687496.