Description
Sutezolid is an analog of linezolid that may be effective treatment for tuberculosis. A study using a PK/PD model has shown that sutezolid is 17-fold more potent than its metabolite U-603 against tuberculosis.
Product Unit Size | Cost | Quantity | Stock |
---|
Sutezolid is an analog of linezolid that may be effective treatment for tuberculosis. A study using a PK/PD model has shown that sutezolid is 17-fold more potent than its metabolite U-603 against tuberculosis.
Cas No. | 168828-58-8 |
---|---|
Purity | ≥98% |
Formula | C16H20FN3O3S |
Formula Wt. | 353.41 |
Chemical Name | (S)-N-((3-(3-fluoro-4-thiomorpholinophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide |
IUPAC Name | N-[[(5S)-3-(3-fluoro-4-thiomorpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide |
Synonym | PNU-100480; U-100480; PF-02341272 |
Store Temp | -20°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Wallis R, Dawson R, Friedrich S, et al. Mycobacterial activity of sutezolid (PNU-100480) in sputum (EBA) and bloowd (WBA) of patients with pulmonary tuberculosis. PLoS One. 2014 Apr 14;9(4):e94462. PMID: 24732289.
Zhu T, Friedrich S, Diacon A, et al. Population pharmacokinetic/pharmacodynamic analysis of the bactericidal activities of sutezolid intracellular Mycobacterium tuberculosis in ex vivo whole-blood cultures of patients with pulmonary tuberculosis. Antimicrob Agents Chemother. 2014 Jun;58(6):3306-3311. PMID: 24687496.
β2-adrenergic agonist, BChE inhibitor.
Synthetic antifungal.
Basic phenol skeleton structure found in variou...
Recombinant HIV glycoprotein antigen fragment.<...
Caffeic acid derivative.
Ellagic acid derivative produced by gut microfl...
ALK, ROS1, c-MET inhibitor.
Coumarin; VKORC1 inhibitor.
NSAID; COX-2 inhibitor.
Thiazolidinedione; PPARγ agonist.
Polycyclic aromatic hydrocarbon (PAH) found in ...
Selective inhibitor of LRRK2.
Amino acid precursor of dopamine.
Synthetic nitrile compound
Inhibitor of TRK.
NSAID; COX-2 inhibitor.
Polyphenol found in many plants and foods.
δ2OR antagonist.
Potential PKD binding agent.
Alkaloid found in Cephalotaxus; ribosomal prote...