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Syntide 2 is a synthetic 15-amino acid peptide. Syntide 2 is a substrate of Ca2+-dependent protein kinase (CDPK), CaMKII, PKC, and other kinases involved in Ca2+ signaling. Syntide 2 is phosphorylated by glutathione S-transferase and is involved in wound-induced signaling cascades.
| Cas No. | 108334-68-5 |
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| Purity | ≥95% |
| Formula | C68H122N20O18 |
| Formula Wt. | 1507.85 |
| IUPAC Name | (2S)-6-amino-2-[[(2S)-6-amino-2-[[2-[[(2S)-1-[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-2-[[(2S)-4-methyl-2-[[(2S)-pyrrolidine-2-carbonyl]amino]pentanoyl]amino]propanoyl]amino]pentanoyl]amino]-3-hydroxybutanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]-3-methylbutanoyl]amino]propanoyl]amino]acetyl]amino]-4-methylpentanoyl]pyrrolidine-2-carbonyl]amino]acetyl]amino]hexanoyl]amino]hexanoic acid |
| Solubility | Soluble in water, 1% acetic acid (1 mg/mL), DMSO. |
| Appearance | White to off white powder |
| Store Temp | -20°C |
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| Ship Temp | Ambient |
| MSDS | |
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| Info Sheet |
Lanteri ML, Pagnussat GC, Lamattina L. Calcium and calcium-dependent protein kinases are involved in nitric oxide- and auxin-induced adventitious root formation in cucumber. J Exp Bot. 2006;57(6):1341-51. PMID: 16531462.
Szczegielniak J, Klimecka M, Liwosz A, et al. A wound-responsive and phospholipid-regulated maize calcium-dependent protein kinase. Plant Physiol. 2005 Dec;139(4):1970-83. PMID: 16299185.
Ishida A, Kameshita I, Okuno S, et al. A novel highly specific and potent inhibitor of calmodulin-dependent protein kinase II. Biochem Biophys Res Commun. 1995 Jul 26;212(3):806-12. PMID: 7626114.
Hashimoto Y, Soderling TR. Calcium calmodulin-dependent protein kinase II and calcium phospholipid-dependent protein kinase activities in rat tissues assayed with a synthetic peptide. Arch Biochem Biophys. 1987 Feb 1;252(2):418-25. PMID: 3028265.