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T2 toxin Triol

T2 toxin Triol

Product ID T0004
Cas No. 34114-98-2
Purity ≥97%, TLC
Product Unit SizeCostQuantityStock
1 mg $452.90 In stock
5 mg $1,811.00 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

T2 toxin triol is a Fusarium trichothecene mycotoxin. In vitro, this compound displays significant cytotoxic activity, inducing breakdown of polyribosomes and inhibiting polypeptide chain elongation in eukaryotes. Additionally, T2 triol exhibits cytotoxicity in Jurkat T cells. This mycotoxin was initially produced by mycoplasma in barley, maize, oats, and other livestock feed grains.

Product Info

Cas No.

34114-98-2

Purity

≥97%, TLC

Formula

C20H30O7

Formula Wt.

382.45

Chemical Name

12,13-Epoxytrichothec-9-ene-3-alpha,4-beta,8-alpha,15-tetrol 8-isovalerate 3-alpha,4-beta,15-Trihydroxy-8-alpha-(3-methylbutyryloxy)-12,13-epoxytrichothec-9-ene

IUPAC Name

[(1S,2R,4S,7R,9R,10R,11S,12S)-10,11-dihydroxy-2-(hydroxymethyl)-1,5-dimethylspiro[8-oxatricyclo[7.2.1.02,7]dodec-5-ene-12,2'-oxirane]-4-yl] 3-methylbutanoate

Synonym

T2 triol, T-2 Triol

Melting Point

162°C

Solubility

DMSO, Dichloromethane, methanol. Slightly soluble in water.

Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

T0004 MSDS PDF

Info Sheet

T0004 Info Sheet PDF

References

Alassane-Kpembi I, Kolf-Clauw M, Gauthier T, et al. New insights into mycotoxin mixtures: the toxicity of low doses of Type B trichothecenes on intestinal epithelial cells is synergistic. Toxicol Appl Pharmacol. 2013 Oct 1;272(1):191-8. PMID: 23735874.

Tan DC, Flematti GR, Ghisalberti EL, et al. Mycotoxins produced by Fusarium species associated with annual legume pastures and 'sheep feed refusal disorders' in Western Australia. Mycotoxin Res. 2011 May;27(2):123-35. PMID: 23605703.

Edwards SG. Fusarium mycotoxin content of UK organic and conventional oats. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2009 Jul;26(7):1063-9. PMID: 19680981.

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