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Tenoxicam

Tenoxicam

Product ID T1654
Cas No. 59804-37-4
Purity ≥98%
Product Unit SizeCostQuantityStock
250 mg $87.90 In stock
1 g $229.30 In stock
5 g $763.70 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Tenoxicam is a non-steroidal anti-inflammatory drug (NSAID) that exhibits anti-inflammatory, analgesic, neuroprotective, and antioxidative activities; it inhibits COX-1 and COX-2. Tenoxicam is clinically used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, tendonitis, and bursitis. In neurons, tenoxicam inhibits MPP+-induced decreases in phosphorylated Akt and also scavenges free radicals, preventing lipid peroxidation.

Product Info

Cas No.

59804-37-4

Purity

≥98%

Formula

C13H11N3O4S2

Formula Wt.

337.38

Chemical Name

4-Hydroxy-2-methyl-N-2-pyridinyl-2H-thieno[2,3-e]- 1,2-thiazine-3-carboxamide 1,1-dioxide

IUPAC Name

4-hydroxy-2-methyl-1,1-dioxo-N-pyridin-2-ylthieno[2, 3-e]thiazine-3-carboxamide

Synonym

Alganex, Dolmen, Liman, Mobiflex, Rexalgan, Tilcotil

Melting Point

209-213°C (dec)

Solubility

Soluble in DMSO, chloroform and methylene chloride.

Appearance

Yellow Crystalline Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

T1654 MSDS PDF

Info Sheet

T1654 Info Sheet PDF

References

Tasaki Y, Yamamoto J, Omura T, et al. Oxicam structure in non-steroidal anti-inflammatory drugs is essential to exhibit Akt-mediated neuroprotection against 1-methyl-4-phenyl pyridinium-induced cytotoxicity. Eur J Pharmacol. 2012 Feb 15;676(1-3):57-63. PMID: 22182582.

Suleyman H, Halici Z, Cadirci E, et al. Indirect role of beta2-adrenergic receptors in the mechanism of anti-inflammatory action of NSAIDS. J Physiol Pharmacol. 2008 Dec;59(4):661-72. PMID: 19212002.

Maffei Facino RM, Carini M, Saibene L. Scavenging of free radicals by tenoxicam: a participating mechanism in the antirheumatic/antiinflammatory efficacy of the drug. Arch Pharm (Weinheim). 1996 Oct;329(10):457-63. PMID: 8933748.

Custom Order

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