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Terbinafine Hydrochloride

Terbinafine Hydrochloride

Product ID T1672
Cas No. 78628-80-5
Purity ≥98%
Product Unit SizeCostQuantityStock
250 mg $71.50 In stock
1 g $173.70 In stock
5 g $694.40 In stock
10 g $1,214.70 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Terbinafine is an allylamine that exhibits anticancer, antifungal, and anti-hyperlipidemic activities. Terbinafine inhibits squalene oxidase, preventing synthesis of ergosterol and cholesterol. Terbinafine also inhibits proliferation of oral squamous cell carcinoma cells, inhibiting kinase suppressor of RAS 1 (KSR1).

Product Info

Cas No.

78628-80-5

Purity

≥98%

Formula

C21H25N • HCl

Formula Wt.

327.90

Chemical Name

N-[(2E)-6,6-Dimethyl-2-hepten-4-ynyl]-N-methyl-1- naphthalenemethanamine hydrochloride

IUPAC Name

(E)-N,6, 6-trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-amine; hydrochloride

Synonym

Lamisil

Melting Point

195-198°C

Solubility

Soluble in methanol, methylene chloride or ethanol.

Appearance

White or off-white powder

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

T1672 MSDS PDF

Info Sheet

T1672 Info Sheet PDF

References

Li B, Lu L, Zhong M, et al. Terbinafine inhibits KSR1 and suppresses Raf-MEK-ERK signaling in oral squamous cell carcinoma cells. Neoplasma. 2013;60(4):406-12. PMID: 23581412.

Nowosielski M, Hoffmann M, Wyrwicz LS, et al. Detailed mechanism of squalene epoxidase inhibition by terbinafine. J Chem Inf Model. 2011 Feb 28;51(2):455-62. PMID: 21229992.

Revankar SG, Nailor MD, Sobel JD. Use of terbinafine in rare and refractory mycoses. Future Microbiol. 2008 Feb;3(1):9-17. PMID: 18230029.

Custom Order

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