LKT Labs

Biochemicals for Life Science Research

Terlipressin Acetate

Terlipressin Acetate

Product ID T1673
Cas No. 14636-12-5
Purity ≥95%
Product Unit SizeCostQuantityStock
1 mg $103.00 In stock
5 mg $210.00 In stock
Bulk Quote

Quicklinks

Description

Terlipressin is a synthetic peptide agonist at vasopressin 1 receptors (AVPR1) and is clinically used to treat portal hypertension by decreasing portal pressure; it is an analog of vasopressin. Terlipressin is a vasopressin analog that exhibits both vasoconstrictive and antihypertensive activities in various models. Terlipressin induces gastroparesis in vivo, increasing slow wave frequency in stomach and intestines. Terlipressin may also improve renal function in subjects with hepatorenal syndrome.

Product Info

Cas No.

14636-12-5
Purity

≥95%
Formula

C52H74N16O15S2
Formula Wt.

1227.37
IUPAC Name

(2S)-1-[(4R,7S,10S,13S,16S,19R)-19-[[2-[[2-[(2-aminoacetyl)amino]acetyl]amino]acetyl]amino]-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-6-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxohexan-2-yl]pyrrolidine-2-carboxamide
Synonym

Glypressin, Lucassin, Terlipressinum
Solubility

Insoluble in water. Soluble in DMSO.
Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C
Ship Temp

Ambient

Downloads

MSDS

T1673 MSDS PDF
Info Sheet

T1673 Info Sheet PDF

References

Lange M, Van Aken H, Westphal M, et al. Role of vasopressinergic V1 receptor agonists in the treatment of perioperative catecholamine-refractory arterial hypotension. Best Pract Res Clin Anaesthesiol. 2008 Jun;22(2):369-81. PMID: 18683482.

Betrosian AP, Agarwal B, Douzinas EE. Acute renal dysfunction in liver diseases. World J Gastroenterol. 2007 Nov 14;13(42):5552-9. PMID: 17948928.

Nowak L, Królczyk G, Sobocki J, et al. Gastric stimulation is effective in reversing vasopressin induced gastroparesis. Folia Med Cracov. 2004;45(1-2):71-9. PMID: 16276827.

Heinemann A, Stauber RE. Effect of terlipressin on in vitro vascular hyporeactivity of portal hypertensive rats. J Hepatol. 1996 Jun;24(6):739-46. PMID: 8835750.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • D3462

    Diphenhydramine Hydrochloride

    Voltage-gated Na+ channel blocker, mAChR antago...

    ≥98%
  • F0150

    Famotidine

    Histamine H2 antagonist, GSK-3β inhibitor.

    ≥98%
  • T564093

    (+)-δ-Tocopherol

    Vitamin E component

    ≥98%
  • I5212

    Indirubin

    Bisindole isomer of indigo found in Indigo natu...

    ≥98%
  • E6846

    Erlotinib Hydrochloride

    EGFR inhibitor.

    ≥98%
  • N3225

    Nigericin Sodium

    Polyether cationic ionophore.

    ≥98%
  • C0160

    Canrenone

    Metabolite of spironolactone; Na+/K+ ATPase par...

    ≥98%
  • D3329

    7,8-Dihydroxyflavone Hydrate

    TrkB agonist.

    ≥99%
  • M0009

    Macitentan

    ET-A/B antagonist.

    ≥99%
  • N3474

    Nisoldipine

    Calcium channel blocker.

    ≥98%
  • T0109

    13-Acetyl-9-dihydrobaccatin-III

    Found in Taxus, starting material for synthesis...

    ≥98%
  • P0218

    Paeoniflorin

    Found in Paeonia; L-type Ca2+ channel blocker.<...

    ≥98%
  • N0212

    Nedaplatin

    Pt-based DNA cross-linker.

    ≥98%
  • P3456

    Pimobendan

    PDE3 inhibitor.

    ≥99%
  • G733404

    GSK3685032

    Reversible DNMT1-selective inhibitor

    ≥98%
  • C9876

    CYT-387

    JAK2 inhibitor.

    ≥98%
  • G733400

    GSK-2578215A

    Selective inhibitor of LRRK2.

    ≥98%
  • P7000

    PR-619

    Deubiquitinating enzyme inhibitor.

    ≥98%
  • L8009

    D-Luciferin 1-(4,5-dimethoxy-2-nitrophenyl) Ethyl Ester

    Cell-membrane permeable heterocyclic light-emit...

    ≥95%
  • P9767

    Pyriproxyfen

    Juvenile insect hormone mimic.

    ≥95%