LKT Labs

Biochemicals for Life Science Research

Terlipressin Acetate

Terlipressin Acetate

Product ID T1673
Cas No. 14636-12-5
Purity ≥95%
Product Unit SizeCostQuantityStock
1 mg $102.90 In stock
5 mg $210.00 In stock
Bulk Quote

Quicklinks

Description

Terlipressin is a synthetic peptide agonist at vasopressin 1 receptors (AVPR1) and is clinically used to treat portal hypertension by decreasing portal pressure; it is an analog of vasopressin. Terlipressin is a vasopressin analog that exhibits both vasoconstrictive and antihypertensive activities in various models. Terlipressin induces gastroparesis in vivo, increasing slow wave frequency in stomach and intestines. Terlipressin may also improve renal function in subjects with hepatorenal syndrome.

Product Info

Cas No.

14636-12-5
Purity

≥95%
Formula

C52H74N16O15S2
Formula Wt.

1227.37
IUPAC Name

(2S)-1-[(4R,7S,10S,13S,16S,19R)-19-[[2-[[2-[(2-aminoacetyl)amino]acetyl]amino]acetyl]amino]-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-6-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxohexan-2-yl]pyrrolidine-2-carboxamide
Synonym

Glypressin, Lucassin, Terlipressinum
Solubility

Insoluble in water. Soluble in DMSO.
Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C
Ship Temp

Ambient

Downloads

MSDS

T1673 MSDS PDF
Info Sheet

T1673 Info Sheet PDF

References

Lange M, Van Aken H, Westphal M, et al. Role of vasopressinergic V1 receptor agonists in the treatment of perioperative catecholamine-refractory arterial hypotension. Best Pract Res Clin Anaesthesiol. 2008 Jun;22(2):369-81. PMID: 18683482.

Betrosian AP, Agarwal B, Douzinas EE. Acute renal dysfunction in liver diseases. World J Gastroenterol. 2007 Nov 14;13(42):5552-9. PMID: 17948928.

Nowak L, Królczyk G, Sobocki J, et al. Gastric stimulation is effective in reversing vasopressin induced gastroparesis. Folia Med Cracov. 2004;45(1-2):71-9. PMID: 16276827.

Heinemann A, Stauber RE. Effect of terlipressin on in vitro vascular hyporeactivity of portal hypertensive rats. J Hepatol. 1996 Jun;24(6):739-46. PMID: 8835750.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • S8098

    SU-1498

    Tyrphostin; VEGFR inhibitor.

    ≥99%
  • R2711

    Recombinant HCV-Core Antigens

    Recombinant HIV core protein antigen fragment.<...

    ≥95%
  • D170310

    10,11-Dehydrocurvularin

    Fungal metabolite produced by Penicillium speci...

    ≥98%
  • C864760

    CVT-313

    Selective CDK2 inhibitor.

    ≥98%
  • F4432

    FLI-06

    Notch inhibitor.

    ≥99%
  • R0212

    Radicicol

    Benzoquinone ansamycin; topoisomerase VI-B, HSP...

    ≥96%
  • SB5776

    Snake venom – Bothrops alternatus (urutu)

    Snake venom found in Bothrops alternatus urutu....

    ≥98%
  • C0247

    Calcineurin Autoinhibitory Peptide

    Peptide; calcineurin inhibitor.

    ≥95%
  • C0149

    Calcitonin, salmon

    Endogenous neuropeptide hormone, lowers extrace...

    ≥98%
  • I6932

    Irinotecan

    Camptothecin analog; topoisomerase I inhibitor,...

    ≥98%
  • G733404

    GSK3685032

    Reversible DNMT1-selective inhibitor

    ≥98%
  • S1061

    Small Cardioactive Peptide B

    Peptide found in molluscs, cardiomodulator.

    ≥95%
  • R1627

    Regorafenib Anhydrous

    Multikinase inhibitor.

    ≥99%
  • P2510

    4-Phenylbutylisothiocyanate

    Synthetic ITC.

    ≥98%
  • P3597

    Pizotyline Malate

    5-HT1A partial agonist, 5-HT2C antagonist.

    ≥98%
  • D324090

    Diclofenac Impurity C

    Impurity of diclofenac

    ≥98%
  • A5160

    Ampicillin Trihydrate

    β-lactam; transpeptidase inhibitor.

    ≥97%
  • D564090

    7-epi-Docetaxel

    Docetaxel impurity

    ≥95%
  • C9808

    CZC-54252

    LRRK2 inhibitor.

    ≥98%
  • R5611

    Rocuronium Bromide

    Non-depolarizing NMJ blocker; nAChR and M2/3 mA...

    ≥98%