LKT Labs

Biochemicals for Life Science Research

Thiabendazole

Thiabendazole

Product ID T2930
Cas No. 148-79-8
Purity ≥98%
Product Unit SizeCostQuantityStock
10 g $75.00 In stock
100 g $147.00 In stock
500 g $331.00 In stock
Bulk Quote

Quicklinks

Description

Thiabendazole is a benzimidazole antifungal that exhibits additional antibiotic activity as well as anticancer chemotherapeutic and anti-angiogenic activities. Thiabendazole binds tubulin and acts as a spindle poison, altering microtubule polymerization and inhibiting growth of Aspergillus. Thiabendazole also displays nematocidal activity against Strongyloides and anti-helminthic activity against Haemonchus. This compound inhibits proliferation, angiogenesis, and VEGF expression in melanoma cells and prevents tumor growth in vivo.

Product Info

Cas No.

148-79-8
Purity

≥98%
Formula

C10H7N3S
Formula Wt.

201.25
Chemical Name

2-(4-Thiazolyl)-1H-benzimidazole

IUPAC Name

4-(1H-benzimidazol-2-yl)-1,3-thiazole
Synonym

MK-360, Thibenzole, Equizole, Mertect, Storite, TBZ, Tecto.
Melting Point

300-303°C
Solubility

Soluble in DMF and DMSO. Slightly soluble in alcohols and esters.
Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient
Ship Temp

Ambient

Downloads

MSDS

T2930 MSDS PDF
Info Sheet

T2930 Info Sheet PDF

References

Zhang J, Zhao C, Gao Y, et al. Thiabendazole, a well-known antifungal drug, exhibits anti-metastatic melanoma B16F10 activity via inhibiting VEGF expression and inducing apoptosis. Pharmazie. 2013 Dec;68(12):962-8. PMID: 24400443.

Satou T, Koga M, Koike K, et al. Nematocidal activities of thiabendazole and ivermectin against the larvae of Strongyloides ratti and S. venezuelensis. Vet Parasitol. 2001 Aug 31;99(4):311-22. PMID: 11511418.

Crebelli R, Conti G, Conti L, et al. In vitro studies with nine known or suspected spindle poisons: results in tests for chromosome malsegregation in Aspergillus nidulans. Mutagenesis. 1991 Mar;6(2):131-6. PMID: 2056914.

Lubega GW, Prichard RK. Specific interaction of benzimidazole anthelmintics with tubulin: high-affinity binding and benzimidazole resistance in Haemonchus contortus. Mol Biochem Parasitol. 1990 Jan 15;38(2):221-32. PMID: 2325707.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • P0092

    Paclitaxel, from Taxus yunnanensis

    Diterpene found in Taxus yunnanensis; microtubu...

    ≥98%
  • A491337

    9-Aminocamptothecin Hydrochloride

    Derivative of camptothecin.

    ≥98%
  • A4400

    Alamethicin

    Antimicrobial peptide found in Trichoderma, ind...

    ≥95%
  • M1752

    Men 10376

    Peptide; NK2 antagonist.

    ≥95%
  • R3249

    Rimantadine Hydrochloride

    Viral M2 proton channel blocker.

    ≥98%
  • A6828

    N(α),N(α)-Dimethyl-L-Arginine Ammonium

    Endogenous amino acid derivative, regulates water/...
    ≥98%
  • H9662

    Hypocrellin B

    Induces DNA strand breakage.

    ≥98%
  • E6896

    Erysolin

    ITC found in cruciferous vegetables, analog of ...

    ≥97%
  • B1978

    Betulin-3-Acetate

    Pentacyclic triterpene found in various plant s...

    ≥97%
  • P1761

    Pepstatin

    Aspartyl protease inhibitor.

    ≥98%
  • C0366

    Carvedilol Phosphate Hemihydrate

    FIASMA; α1- and β1/2-adrenergic antagonist.

    ≥98%
  • A6970

    Artemether

    Sesquiterpene lactone derived from Artemesia.

    ≥98%
  • B177550

    Benzbromarone

    Non-competitive inhibitor of xanthine oxidase.<...

    ≥99%
  • F1607

    Febuxostat

    Xanthine oxidase inhibitor.

    ≥98%
  • N0061

    D-Naproxen

    NSAID; COX-1/2 inhibitor.

    ≥99%
  • P6818

    Prednisolone

    Cortisol derivative; glucocorticoid agonist.

    ≥98%
  • S1853

    Senegenin

    Found in Polygata tennifolia.

    ≥98%
  • R5212

    RN-486

    Btk inhibitor.

    ≥98%
  • K1655

    Kenpaullone

    GSK-3β, HGK, and CDK inhibitor.

    ≥95%
  • H1893

    Hexarelin

    Synthetic ghrelin analog; ghrelin agonist.

    ≥95%