Thiabendazole

Name: Thiabendazole
SKU: T2930
Availability: InStock

Product ID T2930

Cas No. 148-79-8

Purity ≥98%

Product Unit Size	Cost	Quantity		Stock

Bulk Quote

Quicklinks

Description
Product Info
Shipping and Storage
Downloads
References

Description

Thiabendazole is a benzimidazole antifungal that exhibits additional antibiotic activity as well as anticancer chemotherapeutic and anti-angiogenic activities. Thiabendazole binds tubulin and acts as a spindle poison, altering microtubule polymerization and inhibiting growth of Aspergillus. Thiabendazole also displays nematocidal activity against Strongyloides and anti-helminthic activity against Haemonchus. This compound inhibits proliferation, angiogenesis, and VEGF expression in melanoma cells and prevents tumor growth in vivo.

Product Info

Cas No.	148-79-8
Purity	≥98%
Formula	C₁₀H₇N₃S
Formula Wt.	201.25
Chemical Name	2-(4-Thiazolyl)-1H-benzimidazole
IUPAC Name	4-(1H-benzimidazol-2-yl)-1,3-thiazole
Synonym	MK-360, Thibenzole, Equizole, Mertect, Storite, TBZ, Tecto.
Melting Point	300-303°C
Solubility	Soluble in DMF and DMSO. Slightly soluble in alcohols and esters.
Appearance	White to off white powder

Shipping and Storage

Store Temp	Ambient
Ship Temp	Ambient

Downloads

MSDS	T2930 MSDS PDF
Info Sheet	T2930 Info Sheet PDF

References

Zhang J, Zhao C, Gao Y, et al. Thiabendazole, a well-known antifungal drug, exhibits anti-metastatic melanoma B16F10 activity via inhibiting VEGF expression and inducing apoptosis. Pharmazie. 2013 Dec;68(12):962-8. PMID: 24400443.

Satou T, Koga M, Koike K, et al. Nematocidal activities of thiabendazole and ivermectin against the larvae of Strongyloides ratti and S. venezuelensis. Vet Parasitol. 2001 Aug 31;99(4):311-22. PMID: 11511418.

Crebelli R, Conti G, Conti L, et al. In vitro studies with nine known or suspected spindle poisons: results in tests for chromosome malsegregation in Aspergillus nidulans. Mutagenesis. 1991 Mar;6(2):131-6. PMID: 2056914.

Lubega GW, Prichard RK. Specific interaction of benzimidazole anthelmintics with tubulin: high-affinity binding and benzimidazole resistance in Haemonchus contortus. Mol Biochem Parasitol. 1990 Jan 15;38(2):221-32. PMID: 2325707.

Custom Order

Name*
First Last
Company/Institution
Email*
Enter Email Confirm Email
Product ID
Product Name
Unit Size
Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
Unit Label
Quantity
Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
Comments
Name
This field is for validation purposes and should be left unchanged.

Thiabendazole

Quicklinks

Description

Product Info

Shipping and Storage

Downloads

References

Custom Order

Related Products

Duloxetine Hydrochloride

NVP-BGT226

Asciminib

Coptisine Chloride, synthetic

Thioridazine Hydrochloride

Vidarabine Monophosphate

Amastatin Hydrochloride Hydrate

Adipokinetic Hormone, locust

TAK-632

Y-320

KL-1 Peptide

Ractopamine Hydrochloride

Myelin Basic Protein (1-11), human

CEP-37440 Hydrochloride

A 83-01

Tenovin-3

S,S-(+)-Tetrandrine

Vancomycin Hydrochloride

Rutaecarpine, synthetic

StemRegenin 1 Hydrochloride

Footer