LKT Labs

Biochemicals for Life Science Research

Thiabendazole

Thiabendazole

Product ID T2930
Cas No. 148-79-8
Purity ≥98%
Product Unit SizeCostQuantityStock
10 g $75.20 In stock
100 g $147.40 In stock
500 g $330.80 In stock
Bulk Quote

Quicklinks

Description

Thiabendazole is a benzimidazole antifungal that exhibits additional antibiotic activity as well as anticancer chemotherapeutic and anti-angiogenic activities. Thiabendazole binds tubulin and acts as a spindle poison, altering microtubule polymerization and inhibiting growth of Aspergillus. Thiabendazole also displays nematocidal activity against Strongyloides and anti-helminthic activity against Haemonchus. This compound inhibits proliferation, angiogenesis, and VEGF expression in melanoma cells and prevents tumor growth in vivo.

Product Info

Cas No.

148-79-8
Purity

≥98%
Formula

C10H7N3S
Formula Wt.

201.25
Chemical Name

2-(4-Thiazolyl)-1H-benzimidazole

IUPAC Name

4-(1H-benzimidazol-2-yl)-1,3-thiazole
Synonym

MK-360, Thibenzole, Equizole, Mertect, Storite, TBZ, Tecto.
Melting Point

300-303°C
Solubility

Soluble in DMF and DMSO. Slightly soluble in alcohols and esters.
Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient
Ship Temp

Ambient

Downloads

MSDS

T2930 MSDS PDF
Info Sheet

T2930 Info Sheet PDF

References

Zhang J, Zhao C, Gao Y, et al. Thiabendazole, a well-known antifungal drug, exhibits anti-metastatic melanoma B16F10 activity via inhibiting VEGF expression and inducing apoptosis. Pharmazie. 2013 Dec;68(12):962-8. PMID: 24400443.

Satou T, Koga M, Koike K, et al. Nematocidal activities of thiabendazole and ivermectin against the larvae of Strongyloides ratti and S. venezuelensis. Vet Parasitol. 2001 Aug 31;99(4):311-22. PMID: 11511418.

Crebelli R, Conti G, Conti L, et al. In vitro studies with nine known or suspected spindle poisons: results in tests for chromosome malsegregation in Aspergillus nidulans. Mutagenesis. 1991 Mar;6(2):131-6. PMID: 2056914.

Lubega GW, Prichard RK. Specific interaction of benzimidazole anthelmintics with tubulin: high-affinity binding and benzimidazole resistance in Haemonchus contortus. Mol Biochem Parasitol. 1990 Jan 15;38(2):221-32. PMID: 2325707.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • M7200

    MS436

    BRD4 inhibitor.

    ≥99%
  • M1565

    S-Methyl-L-cysteine-S-oxide

    Organosulfur found in cruciferous vegetables; anal...
    ≥95%
  • B560000

    RAD51 inhibitor, B02

    RAD51 inhibitor.

    ≥98%
  • O9702

    Ozagrel Hydrochloride

    TxA2 synthase inhibitor.

    ≥98%
  • C3352

    Cinacalcet Hydrochloride

    Ca2+-sensing receptor agonist.

    ≥99%
  • I544766

    Intepirdine

    Selective 5-HT6 receptor antagonist

    ≥98%
  • A5287

    Angiotensinogen (1-14), human

    Peptide fragment, renin substrate, precursor to...

    ≥95%
  • T0002

    T2 Toxin

    Trichothecene mycotoxin produced by Fusarium, a...

    ≥98%
  • A464766

    Altenuene

    Alternaria mycotoxin which may be found in food...

    ≥98%
  • M577521

    Monascorubrin

    Bulgarialactone azaphilone

    ≥98%
  • S801001

    SU-5402

    Inhibitor of VEGFR and FGFR.

    ≥98%
  • I0516

    I-BET151

    BRD2/3/4 inhibitor.

    ≥98%
  • A985120

    AZD-0156

    Inhibitor of ATM.

    ≥98%
  • A4803

    Amantadine Sulfate

    Viral M2 proton channel blocker, MAO-A, NET, NM...

    ≥98%
  • D1776

    Desmopressin

    Synthetic vasopressin derivative; V2R agonist.<...

    ≥95%
  • T1030

    N-Des-2-methylpropan-2-ol Docetaxel

    N-Des-2-methylpropan-2-ol Docetaxel is an impur...

    ≥90%
  • G7443

    GSK-429286A

    ROCK1/2 inhibitor, potential RSK and p70S6K inh...

    ≥98%
  • A1017

    Aceclofenac

    Diclofenac analog, NSAID; COX-2 inhibitor.

    ≥98%
  • Z161024

    α-Zearalenol

    Mycotoxin that has structural similarity to est...

    ≥98%
  • A488240

    AMG-337

    Selective inhibitor of c-Met.

    ≥99%